Biomaterials for Cancer Therapeutics

Biomaterials for Cancer Therapeutics
Author: Kinam Park
Publsiher: Elsevier
Total Pages: 530
Release: 2013-11-23
Genre: Technology & Engineering
ISBN: 9780857096760

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Cancer can affect people of all ages, and approximately one in three people are estimated to be diagnosed with cancer during their lifetime. Extensive research is being undertaken by many different institutions to explore potential new therapeutics, and biomaterials technology is now being developed to target, treat and prevent cancer. This unique book discusses the role and potential of biomaterials in treating this prevalent disease. The first part of the book discusses the fundamentals of biomaterials for cancer therapeutics. Chapters in part two discuss synthetic vaccines, proteins and polymers for cancer therapeutics. Part three focusses on theranosis and drug delivery systems, whilst the final set of chapters look at biomaterial therapies and cancer cell interaction. This extensive book provides a complete overview of the latest research into the potential of biomaterials for the diagnosis, therapy and prevention of cancer. Biomaterials for cancer therapeutics is an essential text for academics, scientists and researchers within the biomedical industry, and will also be of interest to clinicians with a research interest in cancer therapies and biomaterials. A complete overview of the latest research into the potential of biomaterials for the diagnosis, therapy and prevention of cancer Discusses the fundamentals of biomaterials for cancer therapeutics Discusses synthetic vaccines, proteins and polymers for cancer therapeutics

Biomaterials for Cancer Therapeutics

Biomaterials for Cancer Therapeutics
Author: Kinam Park
Publsiher: Woodhead Publishing Limited
Total Pages: 810
Release: 2020-03
Genre: Electronic Book
ISBN: 0081029837

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Cancer affects people of all ages, and approximately one in three people are estimated to be diagnosed with cancer during their lifetime. Extensive research is being undertaken by many different institutions to explore potential new therapeutics, and biomaterials technology is being developed to target, treat, and prevent cancer. This book discusses the role and potential of biomaterials in treating this prevalent disease. The first part of the book discusses the fundamentals of biomaterials for cancer therapeutics. Part Two discusses synthetic vaccines, proteins, and polymers for cancer therapeutics. Part Three focusses on theranosis and drug delivery systems, while the final set of chapters look at biomaterial therapies and cancer cell interaction. A complete overview of the latest research into the potential of biomaterials for the diagnosis, treatment, and prevention of cancer Discusses how the properties of specific biomaterials make them important in cancer treatment Discusses synthetic vaccines, proteins, and polymers for cancer therapeutics

Biomaterials for Cancer Therapeutics

Biomaterials for Cancer Therapeutics
Author: Kinam Park
Publsiher: Woodhead Publishing
Total Pages: 782
Release: 2020-03-05
Genre: Medical
ISBN: 9780081029848

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Biomaterials for Cancer Therapeutics: Evolution and Innovation, Second Edition, discusses the role and potential of biomaterials in treating this prevalent disease. The first part of the book discusses the fundamentals of biomaterials for cancer therapeutics. Part Two discusses synthetic vaccines, proteins and polymers for cancer therapeutics. Part Three focuses on theranosis and drug delivery systems, while the final set of chapters look at biomaterial therapies and cancer cell interaction. Cancer affects people of all ages, and approximately one in three people are estimated to be diagnosed with cancer during their lifetime. Extensive research is being undertaken by many different institutions to explore potential new therapeutics, and biomaterials technology is being developed to target, treat and prevent cancer. Hence, this book is a welcomed resource to the discussion. Provides a complete overview of the latest research into the potential of biomaterials for the diagnosis, treatment and prevention of cancer Discusses how the properties of specific biomaterials make them important in cancer treatment Covers synthetic vaccines, proteins and polymers for cancer therapeutics

Nanobiomaterials in Cancer Therapy

Nanobiomaterials in Cancer Therapy
Author: Alexandru Grumezescu
Publsiher: William Andrew
Total Pages: 588
Release: 2016-03-22
Genre: Technology & Engineering
ISBN: 9780323428866

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Nanobiomaterials in Cancer Therapy presents the major applications of nanobiomaterials in oncology, offering an up-to-date overview of the latest research in this field. Utilizing nanobiomaterials, novel therapeutic approaches enable significant improvements in drug-loading capacity, formulation stability and drug efficiency. In this book, leading researchers from around the world share their expertise and unique insights. The book covers the fabrication methods of platforms for multimodal and combinatorial therapeutic options, along with simultaneous and real-time cancer imaging, and innovative approaches for oncology by passive or active pathways of multifunctional nanocarriers. The work also classifies and discusses engineered nanobiosystems for cancer therapy, prevention, and low cancer recurrence or relapse. This book will be of interest to postdoctoral researchers, professors and students engaged in the fields of materials science, biotechnology and applied chemistry. It will also be highly valuable to those working in industry, including pharmaceutics and biotechnology companies, medical researchers, biomedical engineers and advanced clinicians. A comprehensive resource for researchers, practitioners and students working in biomedical, biotechnological and engineering fields A valuable guide to recent scientific progress and the latest application methods Discusses novel opportunities and ideas for developing or improving technologies in nanomedicine and nanobiology

Biomaterials for 3D Tumor Modeling

Biomaterials for 3D Tumor Modeling
Author: Subhas C. Kundu,Rui L Reis
Publsiher: Elsevier
Total Pages: 772
Release: 2020-08-22
Genre: Technology & Engineering
ISBN: 9780128181294

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Biomaterials for 3D Tumor Modeling reviews the fundamentals and most relevant areas of the latest advances of research of 3D cancer models, focusing on biomaterials science, tissue engineering, drug delivery and screening aspects. The book reviews advanced fundamental topics, including the causes of cancer, existing cancer models, angiogenesis and inflammation during cancer progression, and metastasis in 3D biomaterials. Then, the most relevant biomaterials are reviewed, including methods for engineering and fabrication of biomaterials. 3D models for key biological systems and types of cancer are also discussed, including lung, liver, oral, prostate, pancreatic, ovarian, bone and pediatric cancer. This book is suitable for those working in the disciplines of materials science, biochemistry, genetics, molecular biology, drug delivery and regenerative medicine. Reviews key biomaterials topics, including synthetic biomaterials, hydrogels, e-spun materials and nanoparticles Provides a comprehensive overview of 3D cancer models for key biological systems and cancer types Includes an overview of advanced fundamental concepts for an interdisciplinary audience in materials science, biochemistry, regenerative medicine and drug delivery

Precision Medicine in Cancer Therapy

Precision Medicine in Cancer Therapy
Author: Daniel D. Von Hoff,Haiyong Han
Publsiher: Springer
Total Pages: 283
Release: 2019-06-17
Genre: Medical
ISBN: 9783030163914

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This book presents the latest advances in precision medicine in some of the most common cancer types, including hematological, lung and breast malignancies. It also discusses emerging technologies that are making a significant impact on precision medicine in cancer therapy. In addition to describing specific approaches that have already entered clinical practice, the book explores new concepts and tools that are being developed. Precision medicine aims to deliver personalized healthcare tailored to a patient’s genetics, lifestyle and environment, and cancer therapy is one of the areas in which it has flourished in recent years. Documenting the latest advances, this book is of interest to physicians and clinical fellows in the front line of the war on cancer, as well as to basic scientists working in the fields of cancer biology, drug development, biomarker discovery, and biomedical engineering. The contributing authors include translational physicians with first-hand experience in precision patient care.

Engineering PH responsive Biomaterials for Cancer Immunotherapy

Engineering PH responsive Biomaterials for Cancer Immunotherapy
Author: Meilyn Sylvestre
Publsiher: Unknown
Total Pages: 252
Release: 2021
Genre: Electronic Book
ISBN: OCLC:1302725437

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Recent advances in immunotherapy have transformed cancer treatment, while highlighting the complex interactions between the immune system and tumors. For delivery of unstable molecules or immunogenic agents, these therapies often employ nanoformulations to deliver therapeutics to diseased tissue while minimizing off-target toxicity. However, delivery of these carriers is severely limited by numerous biological barriers, preventing therapies from reaching sufficient therapeutic concentrations. Carrier accumulation can be enhanced by incorporation of passive and active targeting, and/or stimuli-responsive elements to help steer the carrier to the appropriate diseased tissues, cells, and intracellular compartments. In this work, we seek to engineer new therapies to enhance targeting and delivery of cancer therapeutics by combining both active and passive targeting strategies. Part I motivates tumor-associated macrophages as immunotherapy targets (Chapter 1), leading into our first approach in which we identified a novel targeting ligand that binds to human tumor-associated macrophages and monocytes (Chapter 2). Part II discusses the challenges of peptide delivery in oncology applications (Chapter 3), prefacing our designed peptide-polymer conjugates that passively accumulate in tumors and respond to external pH to facilitate intracellular peptide delivery upon cellular internalization. Using this strategy, we designed a polymeric delivery system to safely deliver (Chapter 4) a variety of immunogenic peptides (Chapters 5, 6, and 7). Part III outlines the challenges in delivering therapeutics past the blood-brain barrier (Chapter 8), and reports the progress on the development of targeted nanoparticles for brain cancer treatment (Chapter 9).

Biomaterials in Translational Medicine

Biomaterials in Translational Medicine
Author: Lei Yang,Sarit Bhaduri,Thomas J. Webster
Publsiher: Academic Press
Total Pages: 358
Release: 2018-11-30
Genre: Technology & Engineering
ISBN: 9780128134788

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Biomaterials in Translational Medicine delivers timely and detailed information on the latest advances in biomaterials and their role and impact in translational medicine. Key topics addressed include the properties and functions of these materials and how they might be applied for clinical diagnosis and treatment. Particular emphasis is placed on basic fundamentals, biomaterial formulations, design principles, fabrication techniques and transitioning bench-to-bed clinical applications. The book is an essential reference resource for researchers, clinicians, materials scientists, engineers and anyone involved in the future development of innovative biomaterials that drive advancement in translational medicine. Systematically introduces the fundamental principles, rationales and methodologies of creating or improving biomaterials in the context of translational medicine Includes the translational or commercialization status of these new biomaterials Provides the reader with enough background knowledge for a fundamental grip of the difficulties and technicalities of using biomaterial translational medicine Directs the reader on how to find other up-to-date sources (i.e. peer reviewed journals) in the field of translational medicine and biomaterials