Challenges in Delivery of Therapeutic Genomics and Proteomics

Challenges in Delivery of Therapeutic Genomics and Proteomics
Author: Ambikanandan Misra
Publsiher: Elsevier
Total Pages: 686
Release: 2010-09
Genre: Medical
ISBN: 032316515X

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Delivery of therapeutic proteomics and genomics represent an important area of drug delivery research. This text describes the basics of genomics and proteomics and highlights the various chemical, physical and biological approaches to protein and gene delivery.

Challenges in Delivery of Therapeutic Genomics and Proteomics

Challenges in Delivery of Therapeutic Genomics and Proteomics
Author: Ambikanandan Misra
Publsiher: Elsevier
Total Pages: 686
Release: 2010-09-09
Genre: Science
ISBN: 0123849659

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Delivery of therapeutic proteomics and genomics represent an important area of drug delivery research. Genomics and proteomics approaches could be used to direct drug development processes by unearthing pathways involved in disease pathogenesis where intervention may be most successful. This book describes the basics of genomics and proteomics and highlights the various chemical, physical and biological approaches to protein and gene delivery. Covers a diverse array of topics from basic sciences to therapeutic applications of proteomics and genomics delivery Of interest to researchers in both academia and industry Highlights what’s currently known and where further research is needed

Nanocarriers Drug Delivery System

Nanocarriers  Drug Delivery System
Author: Nirmal Shah
Publsiher: Springer Nature
Total Pages: 483
Release: 2021-01-22
Genre: Medical
ISBN: 9789813344976

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A suitable drug delivery system is an essential element in achieving efficient therapeutic responses of drug molecules. With this desirability in mind, the book unites different techniques through which extremely small-sized particles can be utilized as a successful carrier for curing chronic as well as life-threatening diseased conditions. This is a highly informative and prudently organized book, providing scientific insight for readers with an interest in nanotechnology. Beginning with an overview of nanocarriers, the book impetuses on to explore other essential ways through which these carriers can be employed for drug delivery to varieties of administrative routes. This book discusses the functional and significant features of nanotechnology in terms of Lymphatic and other drug targeting deliveries. The book is presenting depth acquaintance for various vesicular and particulate nano-drug delivery carriers, utilized successfully in Pharmaceutical as well as in Cosmeceutical industries along with brief information on their related toxicities. In addition, the work also explores the potential applications of nanocarriers in biotechnology sciences for the prompt and safe delivery of nucleic acid, protein, and peptide-based drugs. An exclusive section in the book illuminates the prominence and competent applicability of nanotechnology in the treatment of oral cancer. The persistence of this book is to provide basic to advanced information for different novel carriers which are under scale-up consideration for the extensive commercialization. The book also includes recent discoveries and the latest patents of such nanocarriers. The cutting-edge evidence of these nanocarriers available in this book is beneficial to students, research scholars, and fellows for promoting their advanced research.

Omics Approaches in Breast Cancer

Omics Approaches in Breast Cancer
Author: Debmalya Barh
Publsiher: Springer
Total Pages: 545
Release: 2014-10-13
Genre: Medical
ISBN: 9788132208433

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Breast cancer is the most common cancer in females that accounts for highest cancer specific deaths worldwide. In the last few decades research has proven that breast cancer can be treated if diagnosed at early stages and proper therapeutic strategy is adopted. Omics-based recent approaches have unveiled the molecular mechanism behind the breast tumorigenesis and aid in identification of next-generation molecular markers for early diagnosis, prognosis and even the effective targeted therapy. Significant development has taken place in the field of omics in breast cancer in the last decade. The most promising omics approaches and their outcomes in breast cancer have been presented in this book for the first time. The book covers omics technologies and budding fields such as breast cancer miRNA, lipidomics, epigenomics, proteomics, nutrigenomics, stem cell, pharmacogenomics and personalized medicine and many more along with conventional topics such as breast cancer management etc. It is a research-based reference book useful for clinician-scientists, researchers, geneticists and health care industries involved in various aspects of breast cancer. The book will also be useful for students of biomedicine, pathology and pharmacy.

Manual of Cytogenetics in Reproductive Biology

Manual of Cytogenetics in Reproductive Biology
Author: Pankaj Talwar
Publsiher: JP Medical Ltd
Total Pages: 332
Release: 2014-02-28
Genre: Medical
ISBN: 9789350909928

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Examines the diagnostic role of cytogenetics in improving the outcome of assisted reproductive technologies (ART). Covers basics of genetics, followed by investigative cytogenetics, applied cytogenetics, recent advances, preimplantation and prenatal cytogenetics.

Advanced Pharmaceutical and Herbal Nanoscience for Targeted Drug Delivery Systems Part I

Advanced Pharmaceutical and Herbal Nanoscience for Targeted Drug Delivery Systems Part I
Author: Swarnlata Saraf,Ram Kumar Sahu,Vivek Dave
Publsiher: Bentham Science Publishers
Total Pages: 320
Release: 2022-05-26
Genre: Medical
ISBN: 9789815036527

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This 2-part reference informs readers about the application of drug delivery technologies to herbal medicines. Chapters cover a broad range of major topics on the subject of targeted drug delivery systems. These topics include the application of drug delivery systems for herbal nanomedicines, drug development issues, emerging technologies, adaptations for clinical use, market prospects and challenges of industrial commercialization. Chapters have been contributed by several experts in pharmaceutical chemistry and blend theoretical knowledge with practical aspects of drug delivery. Part I covers the following topics: - Introduction to nanotechnology and herbal-based nanoparticulate systems - Nucleic acid-based therapeutic drug delivery systems - Herbal bioactives: a booster dose for advanced pharmaceutical nanoscience - Pulmonary nano-drug delivery systems - Application of nano-drug delivery systems in improving the therapeutic efficacy of bioactive natural products - PEGylated liposomes - Insulin liposomes - Aquasomes: a promising novel drug carrier - Nanoparticle-aided herbal drugs: therapeutic implications on cholinergic dysfunction with relevance to Alzheimer’s disease - Vitamins based nanomedicine approach - Recent advances in tumor targeting drug delivery systems: fundamentals of advanced pharmaceutical nanoscience - Niosomes: a revolutionary progress in the field of pharmaceutical sciences - Infectious diseases: pharmaceutical nanoscience for targeted drug delivery This reference is a valuable resource for scholars that creates awareness of novel drug delivery systems as well as their promising applications in drug targeting, and nanotherapeutics for specific diseases.

Marine Biomaterials

Marine Biomaterials
Author: Sougata Jana,Subrata Jana
Publsiher: Springer Nature
Total Pages: 392
Release: 2022-05-25
Genre: Medical
ISBN: 9789811653742

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This book provides updated information on marine-based biomedical carriers and their therapeutic potential. Marine biomaterials and bio-based carriers show wide application in pharmaceutical and biomedical fields to deliver small and large molecules. Biomaterial-based composites, scaffolds, or matrix systems are sound systems for controlled and prolonged drug release in target sites and control the premature release of drugs or bioactive compounds. This book discusses essential topics such as the therapeutic potential of marine collagen, management of bone disorders, gene delivery, natural marine compounds in immunomodulation, theranostic applications, tissue engineering, and regeneration. It also describes the use of marine biopolymers in cancer therapy. Different chapters describe the tissue engineering techniques to develop these carriers. Marine biomaterial-based systems are popular for tissue engineering and biomedical imaging. This book is ideal for industry experts, students, and researchers in pharmaceutical sciences and pharmacology.

Frontiers in Molecular Pharming

Frontiers in Molecular Pharming
Author: Muhammad Sarwar Khan
Publsiher: Bentham Science Publishers
Total Pages: 415
Release: 2021-12-09
Genre: Science
ISBN: 9789815036671

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The advent of large-scale production and clinical trials of drugs developed through diverse production routes - involving viruses, microbes, plants, and animals - has increased the demand for an expanded capacity for pharmaceutical manufacturing. The production and purification of expressed proteins accounts for the bulk of the manufacturing costs for new therapeutics. Several pharmaceutical proteins have been synthesized by exploiting plant genetics allowing producers to override conventional approaches used to manufacture pharmaceuticals. The process of inserting a gene into a host organism for the purpose of harvesting a bioactive molecule for therapeutic use is known as molecular pharming. Frontiers in Molecular Pharming covers an array of topics relevant to understanding the structure, function, regulation, and mechanisms of action, biochemical significance, and usage of proteins and peptides as biomarkers, therapeutics, and vaccines for animals and humans. The contributions aim to highlight current progress in three areas, including system biology (in vivo characterization of proteins and peptides), molecular pharming for animals and molecular pharming for humans. The book gives special attention to computational biology tools, production platforms and fields (such as immunoinformatics) and applications of molecular pharming (such as veterinary therapeutics). A balance of theoretical concepts and practical applications is provided through 13 chapters. Frontiers in Molecular Pharming is an invaluable resource for students and researchers of biochemistry, molecular biology, and biotechnology. The book also serves as a springboard for understanding the process of how discoveries in protein and peptide research and its applications are coming to fruition.

Food Molecular Microbiology

Food Molecular Microbiology
Author: Spiros Paramithiotis,Jayanta K Patra
Publsiher: CRC Press
Total Pages: 252
Release: 2019-02-14
Genre: Science
ISBN: 9781351615099

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With the advances in the field of molecular biology, new tools make it possible to conduct in-depth studies in food microbial communities from a molecular perspective. Information from genomic, transcriptomic, proteomic and metabolomic studies can be integrated through bioinformatic applications, thereby improving our understanding of the interactions between biotic and abiotic factors and concomitantly the physiology of starter cultures, spoilage and pathogenic microbiota. Improvements in the speed, accuracy and reliability of food quality and safety assessment have made the foundation stronger for future developments including the exploitation of gene networks and applications of nanotechnology and systems biology. This book reviews all these developments, provides an integrated view of the subject and helps in identifying areas of future development.

Advanced Pharmaceutical and Herbal Nanoscience for Targeted Drug Delivery Systems Part II

Advanced Pharmaceutical and Herbal Nanoscience for Targeted Drug Delivery Systems Part II
Author: Swarnlata Saraf,Ram Kumar Sahu,Vivek Dave
Publsiher: Bentham Science Publishers
Total Pages: 320
Release: 2022-05-30
Genre: Medical
ISBN: 9789815036558

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This 2-part reference informs readers about the application of drug delivery technologies to herbal medicines. Chapters cover a broad range of major topics on the subject of targeted drug delivery systems. These topics include the application of drug delivery systems for herbal nanomedicines, drug development issues, emerging technologies, adaptations for clinical use, market prospects and challenges of industrial commercialization. Chapters have been contributed by several experts in pharmaceutical chemistry and blend theoretical knowledge with practical aspects of drug delivery. Part II covers the following topics: - Pharmaceutical nanosciences and their application in the delivery of various phytoconstituents - Design of cosmeceutical drug delivery systems: the role of nanotechnology in cosmeceuticals - Transfersomes: a novel vesicular transdermal delivery system - Self-nano/micro emulsified drug delivery systems - Phytosomes - The role of nanomedicines in ocular drug delivery systems - Colloidosomes as an efficient novel drug delivery system: an update - Herbal nanoscience: challenges and regulatory perspectives - Vitamins based nanomedicine approach - Dendrimers: a versatile nanoplatform for advanced targeting and bioactive(s) delivery - Targeted drug delivery systems for cells and cell organelles - Liposomes for herbal drug delivery - AI in pharmacy, herbal medicine and drug delivery: sci-fi or reality? This reference is a valuable resource for scholars that creates awareness of novel drug delivery systems as well as their promising applications in drug targeting, and nanotherapeutics for specific diseases.

Foundations of Biomaterials Engineering

Foundations of Biomaterials Engineering
Author: Maria Cristina Tanzi,Silvia Farè,Gabriele Candiani
Publsiher: Academic Press
Total Pages: 572
Release: 2019-03-16
Genre: Technology & Engineering
ISBN: 9780128094594

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Foundations of Biomaterials Engineering provides readers with an introduction to biomaterials engineering. With a strong focus on the essentials of materials science, the book also examines the physiological mechanisms of defense and repair, tissue engineering and the basics of biotechnology. An introductory section covers materials, their properties, processing and engineering methods. The second section, dedicated to Biomaterials and Biocompatibility, deals with issues related to the use and application of the various classes of materials in the biomedical field, particularly within the human body, the mechanisms underlying the physiological processes of defense and repair, and the phenomenology of the interaction between the biological environment and biomaterials. The last part of the book addresses two areas of growing importance: Tissue Engineering and Biotechnology. This book is a valuable resource for researchers, students and all those looking for a comprehensive and concise introduction to biomaterials engineering. Offers a one-stop source for information on the essentials of biomaterials and engineering Useful as an introduction or advanced reference on recent advances in the biomaterials field Developed by experienced international authors, incorporating feedback and input from existing customers

Advances in Animal Disease Diagnosis

Advances in Animal Disease Diagnosis
Author: Suresh Kumar Gahlawat,Sushila Maan
Publsiher: CRC Press
Total Pages: 336
Release: 2021-06-16
Genre: Medical
ISBN: 9781000397376

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Advances in Animal Disease Diagnosis: Infectious animal diseases caused by pathogenic microorganisms such as bacteria, fungi, and viruses threaten the health and well-being of wildlife, livestock and human populations, limit productivity and significantly increase economic losses to each sector. Pathogen de-tection is an important step for the diagnosis and successful treatment of animal diseases as well as control management in farm and field conditions. The conventional techniques employed to diagnose pathogens in livestock species are time-consuming and sometimes give inconclusive results. On the contrary, molecular techniques have the potential to diag-nose known pathogens/conditions quickly, reliably, and unequivocally as well as for novel pathogen detection. New advances in diagnostics and vaccine design using genomics have developed powerful new methods that have also set the stage for the enhanced diagnosis, surveillance, and control of infectious diseases. High-throughput sequencing (HTS), for ex-ample, uses the latest DNA sequencing platforms in the detection, identification, and detailed analysis of both pathogen and host genomes. This book will explore some key opportunities in the context of animal health, such as the detection of new microorganisms and the development of improved diagnosis of emerging or re-emerging diseases and other clinical conditions, viz. biosensors, nanotools, and omics technologies. Features • Details comprehensive knowledge on the latest molecular techniques for animal disease diagnosis and management • Examines how DNA-based diagnostic techniques will assist international efforts to control the introduction of exotic diseases into new geographic areas • Describes the latest molecular assays for the rapid and accurate detection of pathogens • Helps in working towards meeting the global challenge for sustainable food production and the eradication of poverty • With new biotechnological developments, this fully updated book is a treasure trove of the latest information in animal and medical science

Introduction to Biomedical Data Science

Introduction to Biomedical Data Science
Author: Robert Hoyt,Robert Muenchen
Publsiher: Lulu.com
Total Pages: 258
Release: 2019-11-25
Genre: Science
ISBN: 9781794761735

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Introduction to Biomedical Data Science aims to fill the data science knowledge gap experienced by many clinical, administrative and technical staff. The textbook begins with an overview of what biomedical data science is and then embarks on a tour of topics beginning with spreadsheet tips and tricks and ending with artificial intelligence. In between, important topics are covered such as biostatistics, data visualization, database systems, big data, programming languages, bioinformatics, and machine learning. The textbook is available as a paperback and ebook. Visit the companion website at https: //www.informaticseducation.org for more information. Key features: Real healthcare datasets are used for examples and exercises; Knowledge of a programming language or higher math is not required; Multiple free or open source software programs are presented; YouTube videos are embedded in most chapters; Extensive resources chapter for further reading and learning; PowerPoints and an Instructor Manual

Chitin Chitosan

Chitin Chitosan
Author: Rajendra Dongre
Publsiher: BoD – Books on Demand
Total Pages: 382
Release: 2018-07-18
Genre: Science
ISBN: 9781789234060

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Chitin is the second most abundant biopolymer after cellulose and is a resourceful copious and cheap biomaterial discovered in 1859 owing to significant industrial and technological utility. Raw chitin-chitosan resembles keratin in its biological functions. Chitin chemistry vastly developed via innate unparalleled biological features and exceptional physicochemical characters. Chitosan endures assorted chemical/physical modifications easily at free proactive functionalities, yet intact bulk properties are achieved through processing, viz., film, membrane, composite, hybrid, nanofibre, nanoparticle, hydrogel and scaffolds. Rapidly lessen bioresources signify chitosan as an option due to renewable eco-friendliness and drive embryonic myriad applications in S

Transdermal Drug Delivery

Transdermal Drug Delivery
Author: Kevin Ita
Publsiher: Academic Press
Total Pages: 324
Release: 2020-06-12
Genre: Business & Economics
ISBN: 9780128225516

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Transdermal Drug Delivery: Concepts and Application provides comprehensive background knowledge and documents the most recent advances made in the field of transdermal drug delivery. It provides comprehensive and updated information regarding most technologies and formulation strategies used for transdermal drug delivery. There has been recent growth in the number of research articles, reviews, and other types of publications in the field of transdermal drug delivery. Research in this area is active both in the academic and industry settings. Ironically, only about 40 transdermal products with distinct active pharmaceutical ingredients are in the market indicating that more needs to be done to chronicle recent advances made in this area and to elucidate the mechanisms involved. This book will be helpful to researchers in the pharmaceutical and biotechnological industries as well as academics and graduate students working in the field of transdermal drug delivery and professionals working in the field of regulatory affairs focusing on topical and transdermal drug delivery systems. Researchers in the cosmetic and cosmeceutical industries, as well as those in chemical and biological engineering, will also find this book useful. Captures the most recent advancements and challenges in the field of transdermal drug delivery Covers both passive and active transdermal drug delivery strategies Explores a selection of state-of-the-art transdermal drug delivery systems