Computational Immunology

Computational Immunology
Author: Shyamasree Ghosh
Publsiher: CRC Press
Total Pages: 172
Release: 2020-02-17
Genre: Medical
ISBN: 9781351023481

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Computational Immunology: Applications focuses on different mathematical models, statistical tools, techniques, and computational modelling that helps in understanding complex phenomena of the immune system and its biological functions. The book also focuses on the latest developments in computational biology in designing of drugs, targets, biomarkers for early detection and prognosis of a disease. It highlights the applications of computational methods in deciphering the complex processes of the immune system and its role in health and disease. This book discusses the most essential topics, including Next generation sequencing (NGS) and computational immunology Computational modelling and biology of diseases Drug designing Computation and identification of biomarkers Application in organ transplantation Application in disease detection and therapy Computational methods and applications in understanding of the invertebrate immune system Shyamasree Ghosh (MSc, PhD, PGDHE, PGDBI) Scientific Officer (F), is currently working in the School of Biological Sciences, National Institute of Science Education and Research (NISER), Bhubaneswar, DAE, Govt of India, graduated from the prestigious Presidency College Kolkata in 1998. She was awarded the prestigious National Scholarship from the Government of India. She has worked and published extensively in glycobiology, sialic acids, immunology, stem cells and nanotechnology. She has authored several publications that include books and encyclopedia chapters in reputed journals and books.

Computational Immunology

Computational Immunology
Author: Josep Bassaganya-Riera
Publsiher: Academic Press
Total Pages: 210
Release: 2015-10-21
Genre: Medical
ISBN: 9780128037157

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Computational Immunology: Models and Tools encompasses the methodological framework and application of cutting-edge tools and techniques to study immunological processes at a systems level, along with the concept of multi-scale modeling. The book's emphasis is on selected cases studies and application of the most updated technologies in computational modeling, discussing topics such as computational modeling and its usage in immunological research, bioinformatics infrastructure, ODE based modeling, agent based modeling, and high performance computing, data analytics, and multiscale modeling. There are also modeling exercises using recent tools and models which lead the readers to a thorough comprehension and applicability. The book is a valuable resource for immunologists, computational biologists, bioinformaticians, biotechnologists, and computer scientists, as well as all those who wish to broaden their knowledge in systems modeling. Offers case studies with different levels of complexity Provides a detailed view on cutting-edge tools for modeling that are useful to experimentalists with limited computational skills Explores the usage of simulation for hypothesis generation, helping the reader to understand the most valuable points on experimental setting

Computational Immunology

Computational Immunology
Author: Shyamasree Ghosh
Publsiher: CRC Press
Total Pages: 312
Release: 2019-10-14
Genre: Medical
ISBN: 9781351025522

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The immune system is highly complex system with large number of macromolecules, signaling pathways, protein-protein interactions, and gene expressions. Studies from genomics, transcriptomics, metabolomics are generating huge high throughput data that needs to be analyzed for understanding the Immune system in Health and Disease. Computational approaches arehelping in understanding the study of complex biology of immunology and thereby enabling design of therapeutic strategies in diseases like infectious diseases, immunodeficiency, allergic, hypersensitive, autoimmune disorders and diseases like Cancer, HIV etc. Computational Immunology: Basics highlights the basics of the immune system and function in health and disease. This book offers comprehensive coverage of the most essential topics, including Overview of Immunology and computational Immunology Immune organs and cells, antigen, antibody, B, cell, T cell Antigen Processing and presentation Diseases due to abnormalities of the immune system Cancer Biology Shyamasree Ghosh (MSc, PhD, PGDHE, PGDBI), is currently working in the School of Biological Sciences, National Institute of Science Education and Research (NISER), Bhubaneswar, DAE, Govt of India, graduated from the prestigious Presidency College Kolkata in 1998. She was awarded the prestigious National Scholarship from the Government of India. She has worked and published extensively in glycobiology, sialic acids, immunology, stem cells and nanotechnology. She has authored several publications that include books and encyclopedia chapters in reputed journals and books.

Methods and Applications of Computational Immunology

Methods and Applications of Computational Immunology
Author: Victor Greiff,Gur Yaari,Johannes Textor,Benny Chain
Publsiher: Frontiers Media SA
Total Pages: 135
Release: 2020-01-30
Genre: Electronic Book
ISBN: 9782889633883

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Conceptual Modelling in Computational Immunology

Conceptual Modelling in Computational Immunology
Author: Martina Husáková
Publsiher: Tomáš Bruckner
Total Pages: 174
Release: 2015-09-10
Genre: Computers
ISBN: 9788087924020

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Computational immunology offers in silico strategies for understanding of complex processes occurring in the natural immune system of a living organism that are difficult to explore by traditional in vivo or in vitro techniques. The monograph introduces conceptual languages and approaches for modelling biological processes. The Agent Modelling Language is investigated for conceptualisation of immune processes. AML-based diagrams represent properties and processes occurring in a lymph node.

Encyclopedia of Bioinformatics and Computational Biology

Encyclopedia of Bioinformatics and Computational Biology
Author: Anonim
Publsiher: Elsevier
Total Pages: 3284
Release: 2018-08-21
Genre: Medical
ISBN: 9780128114322

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Encyclopedia of Bioinformatics and Computational Biology: ABC of Bioinformatics combines elements of computer science, information technology, mathematics, statistics and biotechnology, providing the methodology and in silico solutions to mine biological data and processes. The book covers Theory, Topics and Applications, with a special focus on Integrative –omics and Systems Biology. The theoretical, methodological underpinnings of BCB, including phylogeny are covered, as are more current areas of focus, such as translational bioinformatics, cheminformatics, and environmental informatics. Finally, Applications provide guidance for commonly asked questions. This major reference work spans basic and cutting-edge methodologies authored by leaders in the field, providing an invaluable resource for students, scientists, professionals in research institutes, and a broad swath of researchers in biotechnology and the biomedical and pharmaceutical industries. Brings together information from computer science, information technology, mathematics, statistics and biotechnology Written and reviewed by leading experts in the field, providing a unique and authoritative resource Focuses on the main theoretical and methodological concepts before expanding on specific topics and applications Includes interactive images, multimedia tools and crosslinking to further resources and databases

Immunological Computation

Immunological Computation
Author: Dipankar Dasgupta,Fernando Nino
Publsiher: CRC Press
Total Pages: 296
Release: 2008-09-12
Genre: Mathematics
ISBN: 1420065467

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Clearly, nature has been very effective in creating organisms that are capable of protecting themselves against a wide variety of pathogens such as bacteria, fungi, and parasites. The powerful information-processing capabilities of the immune system, such as feature extraction, pattern recognition, learning, memory, and its distributive nature provide rich metaphors that researchers are finding very useful for the development of computational models. While some of these models are designed to give us a better understanding of the immune system, other models are being developed to solve complex real-world problems such as anomaly detection, pattern recognition, data analysis (clustering), function optimization, and computer security. Immunological Computation: Theory and Applications is devoted to discussing different immunological mechanisms and their relation to information processing and problem solving. This unique volume presents a compendium of up-to-date work related to immunity-based techniques. After presenting the general abstractions of immune elements and processes used in computational models, it then— Reviews standard procedures, representations, and matching rules that are used in all immunological computation models Covers the details of one of the earliest and most well-known immune algorithms, based on the negative selection (NS) process that occurs in the thymus Examines promising immune models, including those based on danger theory, cytokine network models, and MHC-based models The text goes further to describe a wide variety of applications, which include computer security, the detection and analysis of anomalies and faults, robotics, and data mining among others. To enhance understanding of this emerging field of study, each chapter includes a summary, review questions, and exercises for readers to practice; as well as issues that will require future research.

Killer Cell Dynamics

Killer Cell Dynamics
Author: Dominik Wodarz
Publsiher: Springer Science & Business Media
Total Pages: 220
Release: 2007-04-05
Genre: Mathematics
ISBN: 9780387687339

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This book reviews how mathematical and computational approaches can be useful to help us understand how killer T-cell responses work to fight viral infections. It also demonstrates, in a writing style that exemplifies the point, that such mathematical and computational approaches are most valuable when coupled with experimental work through interdisciplinary collaborations. Designed to be useful to immunoligists and viroligists without extensive computational background, the book covers a broad variety of topics, including both basic immunological questions and the application of these insights to the understanding and treatment of pathogenic human diseases.