Evolution by Tumor Neofunctionalization

Evolution by Tumor Neofunctionalization
Author: Andrei P. Kozlov
Publsiher: Academic Press
Total Pages: 231
Release: 2014-02-19
Genre: Science
ISBN: 0128001658

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Evolution by Tumor Neofunctionalization explores the possibility of the positive role of tumors in evolution of multicellular organisms. This unique perspective goes beyond recent publications on how evolution may influence tumors, to consider the possible role of tumors in evolution. Widespread in nature tumors represent a much broader category than malignant tumors only. The majority of tumors in humans and other animals may never undergo malignant transformation. Tumors may differentiate with the loss of malignancy, and malignant tumors may spontaneously regress. Cellular oncogenes and tumor suppressor genes play roles in normal development. Many features of tumors could be used in evolution, and there are examples of tumors that have played a role in evolution. This book will stimulate thinking on this topic by specialists in the fields of evolutionary biology, oncology, molecular biology, molecular evolution, embryology, evo-devo, tumor immunology, pathology and clinical oncology. Covers the role that tumors might play in evolution. Provides multidisciplinary approach that will appeal to a wide circle of professionals in the fields of evolutionary biology, oncology, molecular biology, and more

Evolution by Tumor Neofunctionalization

Evolution by Tumor Neofunctionalization
Author: Andrei P. Kozlov
Publsiher: Academic Press
Total Pages: 248
Release: 2014-02-15
Genre: Science
ISBN: 9780128004982

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Evolution by Tumor Neofunctionalization explores the possibility of the positive role of tumors in evolution of multicellular organisms. This unique perspective goes beyond recent publications on how evolution may influence tumors, to consider the possible role of tumors in evolution. Widespread in nature tumors represent a much broader category than malignant tumors only. The majority of tumors in humans and other animals may never undergo malignant transformation. Tumors may differentiate with the loss of malignancy, and malignant tumors may spontaneously regress. Cellular oncogenes and tumor suppressor genes play roles in normal development. Many features of tumors could be used in evolution, and there are examples of tumors that have played a role in evolution. This book will stimulate thinking on this topic by specialists in the fields of evolutionary biology, oncology, molecular biology, molecular evolution, embryology, evo-devo, tumor immunology, pathology and clinical oncology. Covers the role that tumors might play in evolution. Provides multidisciplinary approach that will appeal to a wide circle of professionals in the fields of evolutionary biology, oncology, molecular biology, and more

Macroevolution

Macroevolution
Author: Emanuele Serrelli,Nathalie Gontier
Publsiher: Springer
Total Pages: 403
Release: 2015-02-13
Genre: Science
ISBN: 9783319150451

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This book is divided in two parts, the first of which shows how, beyond paleontology and systematics, macroevolutionary theories apply key insights from ecology and biogeography, developmental biology, biophysics, molecular phylogenetics and even the sociocultural sciences to explain evolution in deep time. In the second part, the phenomenon of macroevolution is examined with the help of real life-history case studies on the evolution of eukaryotic sex, the formation of anatomical form and body-plans, extinction and speciation events of marine invertebrates, hominin evolution and species conservation ethics. The book brings together leading experts, who explain pivotal concepts such as Punctuated Equilibria, Stasis, Developmental Constraints, Adaptive Radiations, Habitat Tracking, Turnovers, (Mass) Extinctions, Species Sorting, Major Transitions, Trends and Hierarchies – key premises that allow macroevolutionary epistemic frameworks to transcend microevolutionary theories that focus on genetic variation, selection, migration and fitness. Along the way, the contributing authors review ongoing debates and current scientific challenges; detail new and fascinating scientific tools and techniques that allow us to cross the classic borders between disciplines; demonstrate how their theories make it possible to extend the Modern Synthesis; present guidelines on how the macroevolutionary field could be further developed; and provide a rich view of just how it was that life evolved across time and space. In short, this book is a must-read for active scholars and because the technical aspects are fully explained, it is also accessible for non-specialists. Understanding evolution requires a solid grasp of above-population phenomena. Species are real biological individuals and abiotic factors impact the future course of evolution. Beyond observation, when the explanation of macroevolution is the goal, we need both evidence and theory that enable us to explain and interpret how life evolves at the grand scale.

Progress in Botany Vol 81

Progress in Botany Vol  81
Author: Francisco M. Cánovas,Ulrich Lüttge,Christoph Leuschner,María-Carmen Risueño
Publsiher: Springer Nature
Total Pages: 399
Release: 2020-01-23
Genre: Science
ISBN: 9783030363277

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With one volume each year, this series keeps scientists and advanced students informed of the latest developments and results in all areas of the plant sciences. The present volume includes reviews on plant physiology, biochemistry, genetics and genomics, forests, and ecosystems.

Understanding Human Anatomy Through Evolution Second Edition

Understanding Human Anatomy Through Evolution   Second Edition
Author: Bruce D. Olsen
Publsiher: Lulu.com
Total Pages: 232
Release: 2009-05-09
Genre: Evolution (Biology)
ISBN: 9780578021645

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Mr. Olsen wrote this book on human anatomy from an evolutionary perspective for college undergraduates with no previous college-level math or science. It contains an introduction to the nature of science and biological evolution in addition to a clear and comprehensive description of basic human anatomy. With over one hundred references, a detailed index, and more than 40 black-and-white illustrations and tables, this book is the perfect supplement to a standard anatomical atlas or textbook with color illustrations.

Homology Genes and Evolutionary Innovation

Homology  Genes  and Evolutionary Innovation
Author: Günter P. Wagner
Publsiher: Princeton University Press
Total Pages: 496
Release: 2018-07-10
Genre: Science
ISBN: 9780691180670

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A major synthesis of homology, written by a top researcher in the field Homology—a similar trait shared by different species and derived from common ancestry, such as a seal's fin and a bird’s wing—is one of the most fundamental yet challenging concepts in evolutionary biology. This groundbreaking book provides the first mechanistically based theory of what homology is and how it arises in evolution. Günter Wagner, one of the preeminent researchers in the field, argues that homology, or character identity, can be explained through the historical continuity of character identity networks—that is, the gene regulatory networks that enable differential gene expression. He shows how character identity is independent of the form and function of the character itself because the same network can activate different effector genes and thus control the development of different shapes, sizes, and qualities of the character. Demonstrating how this theoretical model can provide a foundation for understanding the evolutionary origin of novel characters, Wagner applies it to the origin and evolution of specific systems, such as cell types; skin, hair, and feathers; limbs and digits; and flowers. The first major synthesis of homology to be published in decades, Homology, Genes, and Evolutionary Innovation reveals how a mechanistically based theory can serve as a unifying concept for any branch of science concerned with the structure and development of organisms, and how it can help explain major transitions in evolution and broad patterns of biological diversity.

Basics in Human Evolution

Basics in Human Evolution
Author: Michael P Muehlenbein
Publsiher: Academic Press
Total Pages: 584
Release: 2015-07-24
Genre: Science
ISBN: 9780128026939

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Basics in Human Evolution offers a broad view of evolutionary biology and medicine. The book is written for a non-expert audience, providing accessible and convenient content that will appeal to numerous readers across the interdisciplinary field. From evolutionary theory, to cultural evolution, this book fills gaps in the readers’ knowledge from various backgrounds and introduces them to thought leaders in human evolution research. Offers comprehensive coverage of the wide ranging field of human evolution Written for a non-expert audience, providing accessible and convenient content that will appeal to numerous readers across the interdisciplinary field Provides expertise from leading minds in the field Allows the reader the ability to gain exposure to various topics in one publication

Environmental Epigenetics

Environmental Epigenetics
Author: L. Joseph Su,Tung-chin Chiang
Publsiher: Springer
Total Pages: 321
Release: 2015-05-18
Genre: Medical
ISBN: 9781447166788

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This book examines the toxicological and health implications of environmental epigenetics and provides knowledge through an interdisciplinary approach. Included in this volume are chapters outlining various environmental risk factors such as phthalates and dietary components, life states such as pregnancy and ageing, hormonal and metabolic considerations and specific disease risks such as cancer cardiovascular diseases and other non-communicable diseases. Environmental Epigenetics imparts integrative knowledge of the science of epigenetics and the issues raised in environmental epidemiology. This book is intended to serve both as a reference compendium on environmental epigenetics for scientists in academia, industry and laboratories and as a textbook for graduate level environmental health courses. Environmental Epigenetics imparts integrative knowledge of the science of epigenetics and the issues raised in environmental epidemiology. This book is intended to serve both as a reference compendium on environmental epigenetics for scientists in academia, industry and laboratories and as a textbook for graduate level environmental health courses.

Genes and Evolution

Genes and Evolution
Author: Anonim
Publsiher: Academic Press
Total Pages: 412
Release: 2016-06-06
Genre: Science
ISBN: 9780124172012

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Genes and Evolution, the latest volume in the Current Topics in Developmental Biology series, covers genes and evolution, with contributions from an international board of authors. The chapters provide a comprehensive set of reviews covering such topics as genes and plant domestication, gene networks, phenotypic loss in vertebrates, reproducible evolutionary changes, and epithelial tissue. Covers the area of genes and evolution Contains invaluable contributions from an international board of authors Provides a comprehensive set of reviews covering such topics as genes and plant domestication, gene networks, phenotypic loss in vertebrates, reproducible evolutionary changes and epithelial tissue

Lectures on General Pathology

Lectures on General Pathology
Author: Julius Cohnheim
Publsiher: Unknown
Total Pages: 135
Release: 1889
Genre: Animal heat
ISBN: UBBE:UBBE-00118884

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Neurobiology of Motor Control

Neurobiology of Motor Control
Author: Scott L. Hooper,Ansgar Büschges
Publsiher: John Wiley & Sons
Total Pages: 512
Release: 2017-06-21
Genre: Medical
ISBN: 9781118873625

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A multi-disciplinary look at the current state of knowledge regarding motor control and movement—from molecular biology to robotics The last two decades have seen a dramatic increase in the number of sophisticated tools and methodologies for exploring motor control and movement. Multi-unit recordings, molecular neurogenetics, computer simulation, and new scientific approaches for studying how muscles and body anatomy transform motor neuron activity into movement have helped revolutionize the field. Neurobiology of Motor Control brings together contributions from an interdisciplinary group of experts to provide a review of the current state of knowledge about the initiation and execution of movement, as well as the latest methods and tools for investigating them. The book ranges from the findings of basic scientists studying model organisms such as mollusks and Drosophila, to biomedical researchers investigating vertebrate motor production to neuroengineers working to develop robotic and smart prostheses technologies. Following foundational chapters on current molecular biological techniques, neuronal ensemble recording, and computer simulation, it explores a broad range of related topics, including the evolution of motor systems, directed targeted movements, plasticity and learning, and robotics. Explores motor control and movement in a wide variety of organisms, from simple invertebrates to human beings Offers concise summaries of motor control systems across a variety of animals and movement types Explores an array of tools and methodologies, including electrophysiological techniques, neurogenic and molecular techniques, large ensemble recordings, and computational methods Considers unresolved questions and how current scientific advances may be used to solve them going forward Written specifically to encourage interdisciplinary understanding and collaboration, and offering the most wide-ranging, timely, and comprehensive look at the science of motor control and movement currently available, Neurobiology of Motor Control is a must-read for all who study movement production and the neurobiological basis of movement—from molecular biologists to roboticists.

Interactive Web Based Data Visualization with R plotly and shiny

Interactive Web Based Data Visualization with R  plotly  and shiny
Author: Carson Sievert
Publsiher: CRC Press
Total Pages: 12
Release: 2020-01-28
Genre: Business & Economics
ISBN: 9780429824203

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The richly illustrated Interactive Web-Based Data Visualization with R, plotly, and shiny focuses on the process of programming interactive web graphics for multidimensional data analysis. It is written for the data analyst who wants to leverage the capabilities of interactive web graphics without having to learn web programming. Through many R code examples, you will learn how to tap the extensive functionality of these tools to enhance the presentation and exploration of data. By mastering these concepts and tools, you will impress your colleagues with your ability to quickly generate more informative, engaging, and reproducible interactive graphics using free and open source software that you can share over email, export to pdf, and more. Key Features: Convert static ggplot2 graphics to an interactive web-based form Link, animate, and arrange multiple plots in standalone HTML from R Embed, modify, and respond to plotly graphics in a shiny app Learn best practices for visualizing continuous, discrete, and multivariate data Learn numerous ways to visualize geo-spatial data This book makes heavy use of plotly for graphical rendering, but you will also learn about other R packages that support different phases of a data science workflow, such as tidyr, dplyr, and tidyverse. Along the way, you will gain insight into best practices for visualization of high-dimensional data, statistical graphics, and graphical perception. The printed book is complemented by an interactive website where readers can view movies demonstrating the examples and interact with graphics.

New World Tarantulas

New World Tarantulas
Author: Fernando Pérez-Miles
Publsiher: Springer Nature
Total Pages: 540
Release: 2020-12-15
Genre: Science
ISBN: 9783030486440

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The Theraphosidae are the most famous and diverse mygalomorph spiders, and include some of the largest arachnids on earth. Their unique defense mechanisms, predatory tactics, reproductive strategies and ecological adaptations are displayed by a wide range of terrestrial, burrowing and arboreal species. These arachnids are familiar to the general public thanks to horror movies and a growing interest in tarantulas as pets; however, scientific information on the group is scattered throughout the literature and not easily available. This book reviews all major aspects of New World Theraphosid tarantulas and provides in-depth information on their evolution, taxonomy, behavior, physiology, ecology, reproduction, conservation and biogeography. As a comprehensive guide to the biology of tarantulas, it will appeal to researchers, students and terrarium hobbyists alike.

The Science of Flavonoids

The Science of Flavonoids
Author: Erich Grotewold
Publsiher: Springer Science & Business Media
Total Pages: 274
Release: 2008
Genre: Science
ISBN: 0387745505

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This is the only book of its kind to provide an overview of the science of flavonoids in plants.

Evolution by Gene Duplication

Evolution by Gene Duplication
Author: Susumu Ohno
Publsiher: Springer Science & Business Media
Total Pages: 160
Release: 2013-12-11
Genre: Medical
ISBN: 9783642866593

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It is said that "necessity is the mother of invention". To be sure, wheels and pulleys were invented out of necessity by the tenacious minds of upright citi zens. Looking at the history of mankind, however, one has to add that "Ieisure is the mother of cultural improvement". Man's creative genius flourished only when his mind, freed from the worry of daily toils, was permitted to entertain apparently useless thoughts. In the same manner, one might say with regard to evolution that "natural selection mere(y tnodifted, while redundanry created". Natural selection has been extremely effective in policing alleHe mutations which arise in already existing gene loci. Because of natural selection, organisms have been able to adapt to changing environments, and by adaptive radiation many new species were created from a common ancestral form. Y et, being an effective policeman, natural selection is extremely conservative by nature. Had evolution been entirely dependent upon natural selection, from a bacterium only numerous forms of bacteria would have emerged. The creation of metazoans, vertebrates and finally mammals from unicellular organisms would have been quite impos sible, for such big leaps in evolution required the creation of new gene loci with previously nonexistent functions. Only the cistron which became redun dant was able to escape from the relentless pressure of natural selection, and by escaping, it accumulated formerly forbidden mutations to emerge as a new gene locus.