The Human Hypothalamus

The Human Hypothalamus
Author: Dick F. Swaab,Ruud M. Buijs,Paul J. Lucassen,Ahmad Salehi,Felix Kreier
Publsiher: Elsevier
Total Pages: 566
Release: 2021-07-04
Genre: Science
ISBN: 9780128206843

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The Human Hypothalamus: Neuroendocrine Disorders, Volume 181 in the Handbook of Clinical Neurology series, provides comprehensive summaries of recent research on the brain and nervous system as they relate to clinical neurology. This volume summarizes the role of the hypothalamus in neuroendocrine disorders, identifying the mechanism of action, disorder etiology, and best practices for assessment and treatment. Disorders covered include pituitary hypothalamic disorders of development and growth, hypothalamic tumor related disorders, hypothalamic autoimmune disorders and infection, disorders of vasopressin, water and sodium homeostasis, eating disorders, and gonadotropic hormone regulation disorders. Discusses the importance of the hypothalamus in human growth and development Reviews hypothalamic related tumors, as well as pituitary, autoimmune, vasopressin and hormone regulation disorders Includes metabolic and eating disorders Identifies mechanisms of disease action and etiology Provides best practice information for assessment and treatment

Neuroendocrine Disorders in Children

Neuroendocrine Disorders in Children
Author: Mehul Dattani,Peter Hindmarsh,Lucinda Carr,Iain Robinson
Publsiher: Mac Keith Press
Total Pages: 422
Release: 2016-11-14
Genre: Medical
ISBN: 1909962503

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Impairments in the interaction between the central nervous system and the endocrine system can lead to a number of disorders in children. These include type 1 diabetes, growth disorders, adrenal thyroid and pituitary problems, Addison’s disease and Cushing syndrome, among others. Neuroendocrine Disorders in Children provides a comprehensive examination of paediatric and adolescent disorders focusing on the basic science and its clinical relevance. Complex issues are discussed in an easy-to-follow manner and the latest developments in the area are reviewed. This volume will become invaluable reading for paediatric endocrinologists, paediatric and adult neurologists and trainee paediatricians. Sections in the book cover The GH-IGF1 axis and the brain The thyroid axis and the brain Regulation of appetite and weight Effects of treatment of cancer on the neuroendocrine system Adrenal disorders and the brain Neuroendocrinology and the reproductive axis Neurological complications of diabetes mellitus

The Human Hypothalamus

The Human Hypothalamus
Author: Gabriel I. Uwaifo
Publsiher: Springer Nature
Total Pages: 528
Release: 2020-12-24
Genre: Medical
ISBN: 9783030621872

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The hypothalamus is an anatomically small but functionally important part of the brain. In functional and pathophysiological terms, the hypothalamus represents the intersection of several areas of clinical and medical expertise. The human hypothalamus can be astutely referred to as the crossroad of endocrinology, psychiatry, neurology and neurosurgery. Because of its involvement in myriad physiologic functions and the varied ways disorders involving it can manifest, hypothalamic disease can initially come to medical attention in widely disparate settings and with widely different clinicians. Therefore, the detection and proper care of hypothalamic dysfunction and disease often requires carefully coordinated multidisciplinary care. This volume fills a significant void in the medical professional community, comprehensively presenting the scope of hypothalamic structure, function, dysfunction and disease to cater to the various clinical, teaching and research professionals that have a stake in this part of the human brain. This text captures in one place all the information that practicing clinicians, clinician scientists, and researchers need to be adequately informed about various aspects of the hypothalamus in all its complexity. It is comprehensive and broad in scope so that it provides relevant reference information for the wide range of professionals involved in the pre- and post-mortem detection, diagnosis, characterization, care and management of various hypothalamic disorders and diseases in addition to providing a sound anatomic and physiologic foundation of the normal human hypothalamus. The Human Hypothalamus can be used to differing degrees by medical professionals and students alike, finding utility for interested general clinicians, medical school and allied health professional teaching faculty as well as subspecialists in domains as wide as neurosurgery, neuroendocrinology, clinical psychiatry and neuro-oncology.

Cellular Endocrinology in Health and Disease

Cellular Endocrinology in Health and Disease
Author: Alfredo Ulloa-Aguirre,P. Michael Conn
Publsiher: Elsevier
Total Pages: 414
Release: 2014-02-12
Genre: Medical
ISBN: 9780124167124

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Cellular Endocrinology in Health and Disease describes the underlying basis of endocrine function, providing an important tool to understand the fundamentals of endocrine diseases. Delivering a comprehensive review of the basic science of endocrinology, from cell biology to human disease, this work explores and dissects the function of a number of cellular systems. Among these are those whose function was not obvious until recently, including the endocrine functions of bone and the adipose tissue. Providing content that crosses disciplines, Cellular Endocrinology in Health and Disease details how cellular endocrine function contributes to system physiology and mediates endocrine disorders. A methods section proves novel and useful approaches across research focus that will be attractive to medical students, residents, and specialists in the field of endocrinology, as well as to those interested in cellular regulation. Editors Alfredo Ulloa-Aguirre and P. Michael Conn, experts in molecular and cellular aspects of endocrinology, deliver contributions carefully selected for relevance, impact, and clarity of expression from leading field experts. Covers systemic endocrine action at the cellular level in both health and disease Delivers information on the integration of cell identity and endocrinology Incorporates recent developments in endocrinology to provide an up-to-date reference to researchers

Neuroendocrine Immunological Interactions in Health and Disease

Neuroendocrine Immunological Interactions in Health and Disease
Author: Vinicius Frias Carvalho,Ana Rosa Pérez,Clarissa M. Maya-Monteiro
Publsiher: Frontiers Media SA
Total Pages: 135
Release: 2021-10-21
Genre: Medical
ISBN: 9782889715251

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Glial Neuronal Signaling in Neuroendocrine Systems

Glial Neuronal Signaling in Neuroendocrine Systems
Author: Jeffrey G. Tasker,Jaideep S. Bains,Julie A. Chowen
Publsiher: Springer Nature
Total Pages: 324
Release: 2021-04-01
Genre: Medical
ISBN: 9783030623838

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This volume discusses current research on glial-neuronal interactions in several neuroendocrine systems. Glial-neuronal bidirectional transmission represents one of the fastest-growing areas of investigation in neuroscience today. Unraveling the interactions and signaling synergy between glial cells and neurons is critical to advancing our understanding of brain function. Consequently, this book summarizes the latest findings on the roles of astrocytes, microglia and tanycytes in the control of synaptic transmission, synaptic plasticity, blood-brain signaling, neuroinflammation and immune signaling. In addition, leading experts in the field discuss how reproductive function, the stress response and energy homeostasis are regulated by glial-neuronal communication. Given its scope, the book is essential reading for undergraduate and graduate students in the neurosciences, as well as postdoctoral fellows and established researchers who are looking for a comprehensive overview of glial-neuronal crosstalk in neuroendocrine systems. This is the eleventh volume in the International Neuroendocrine Federation (INF) Masterclass in Neuroendocrinology series (Volumes 1-7 published by Wiley), which aims to illustrate the highest standards and highlight the latest technologies in basic and clinical research, and aspires to provide inspiration for further exploration into the exciting field of neuroendocrinology.

Neuroendocrine Control of Feeding Behavior

Neuroendocrine Control of Feeding Behavior
Author: Serge H. Luquet,Riccarda Granata,Hubert Vaudry
Publsiher: Frontiers Media SA
Total Pages: 135
Release: 2019-11-20
Genre: Electronic Book
ISBN: 9782889632022

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The hypothalamus plays a crucial role in the regulation of food intake and energy homeostasis. Hypothalamic neuronal circuits thus represent a privileged target for the treatment of eating disorders and metabolic diseases. The present eBook constitutes a unique collection of research articles and reviews that highlight new concepts and recent findings about the neuroendocrine control of feeding behavior.

The Human Hypothalamus

The Human Hypothalamus
Author: Dick F. Swaab,Ruud M. Buijs,Felix Kreier,Paul J. Lucassen,Ahmad Salehi
Publsiher: Elsevier
Total Pages: 745
Release: 2021-09-06
Genre: Science
ISBN: 0128199733

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The Handbooks of Neurology provide comprehensive summaries of recent research on the brain and nervous system as they relate to clinical neurology. This volume identifies the neurobiology and neurophysiology of disorders relating to the hypothalamus and provides treatment information for these disorders. Disorders covered include neuropsychiatric, neurodegenerative, periodic, and autoimmune disorders. Coverage includes Alzheimer's, Parkinson's, epilepsy, sleep, pain, depression, anxiety, OCD, PTSD, schizophrenia, autism, aggressions, addiction, and more. Summarizes research on how the hypothalamus relates to neurological disorders Contains neuropsychiatric, neurodegenerative, periodic, and autonomic disorders Includes the neurobiology of, and treatment for, each disorder Covers depression, anxiety, OCD, PTSD, schizophrenia, autism, aggression, addiction and more Provides coverage of sleep and pain

Quality of Life Impairment in Schizophrenia Mood and Anxiety Disorders

Quality of Life Impairment in Schizophrenia  Mood and Anxiety Disorders
Author: A. George Awad
Publsiher: Springer Science & Business Media
Total Pages: 388
Release: 2007-06-28
Genre: Medical
ISBN: 9781402057793

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A fascinating and worthy text that presents new insights into a hugely important area of mental health. Health-related quality of life (HRQL) impairment is a core domain of prevalent mental disorders such as schizophrenia, schizoaffective, mood and anxiety disorders. The authors present a new conceptual framework for this field by explaining how HRQL impairment arises from interactions between various multidimensional factors. They suggest several ways in which further research could enhance our understanding of HRQL impairment, its biological basis, and its relevance to psychopathology.

Neuroendocrinology in Physiology and Medicine

Neuroendocrinology in Physiology and Medicine
Author: P. Michael Conn,Marc E. Freeman
Publsiher: Springer Science & Business Media
Total Pages: 574
Release: 1999-10-06
Genre: Medical
ISBN: 9781592597079

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A panel of leading experts integrate the latest findings from basic and clinical science to create a comprehensive treatment of the processes by which the brain acts as an endocrine organ, not only to control hormonal functions, but also to maintain homeostasis and regulate behavior. The authors-recognized both as leaders in their fields and as skilled teachers-provide systematic coverage of the analytical, anatomical, functional, clinical, and pathological aspects of neuroendocrinology. Topics range from the interactions between the nervous and endocrine systems to the regulation of reproduction, development, metabolism, fluid balance, and biological rhythms. Neuroendocrinology in Physiology and Medicine offers an unprecedented marriage of clinical and basic knowledge that has been missing from classical neuroscience, endocrinology, and physiology texts. It will teach today's medical students and serve researchers as a valuable reference to this rapidly growing field.

The Hypothalamus

The Hypothalamus
Author: Association for Research in Nervous and Mental Disease
Publsiher: Unknown
Total Pages: 490
Release: 1978
Genre: Hormones hypothalamiques
ISBN: UOM:39015001636953

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Neuroendocrine immune Interactions

Neuroendocrine immune Interactions
Author: Rolf C. Gaillard
Publsiher: Karger Medical and Scientific Publishers
Total Pages: 134
Release: 2002
Genre: Medical
ISBN: 9783805572828

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Interactions between the immune, endocrine and nervous systems seldom appear as main issues in the neurosciences and in immunology. So far this was most likely due to the need to focus on the molecular and cellular bases of single neural, endocrine and immune processes. But hormones, neurotransmitters and neuropeptides can also influence more subtle mechanisms underlying immune cell activity. The contents of this volume aim at listing some aspects which show that not only the bases for neuroendocrine control of more refined mechanisms related to the organization and functioning of the immune systems to exist, but also that the immune system can actively communicate with neuroendocrine structures. The evidence is divided into three categories: - Anatomical, cellular and molecular bases for the exchange of information between immune, endocrine and neural cells, - reciprocal effects between immune and neuroendocrine mechanisms, and - immune-neuroendocrine regulatory circuits. Immunologically triggered neuroendocrine responses can be either beneficial or deleterious for the host. A systematic approach would imply the simultaneous evaluation of neuroendocrine and immune parameters and thus provide the basis for therapeutic interventions based on antagonizing or blocking undesirable effects.

The Hypothalamus Pituitary Adrenal Axis

The Hypothalamus Pituitary Adrenal Axis
Author: Anonim
Publsiher: Elsevier
Total Pages: 416
Release: 2008-09-12
Genre: Medical
ISBN: 0080559360

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The hypothalamic-pituitary-adrenal axis controls reactions to stress and regulates various body processes such as digestion, the immune system, mood and sexuality, and energy usage. This volume focuses on the role it plays in the immune system and provides substantive experimental and clinical data to support current understanding in the field, and potential applications of this knowledge in the treatment of disease. * Evidence presented in this book suggests that the nervous, endocrine, and immune systems form the Neuroendoimmune Supersystem, which integrates all the biological functions of higher organisms both in health and disease for their entire life cycle. * Contributors include both the scientists who initiated the work on the HPA axis and on the autonomic nervous system, and those who joined the field later.

Development of the Hypothalamus

Development of the Hypothalamus
Author: Gonzalo Alvarez-Bolado,Valery Grinevich,Luis Puelles
Publsiher: Unknown
Total Pages: 135
Release: 2015-08-06
Genre: Electronic Book
ISBN: 9782889196340

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The hypothalamus is the region of the brain in charge of the maintenance of the internal milieu of the organism. It is also essential to orchestrate reproductive, parental, aggressive-defensive, and other social behaviors, and for the expression of emotions. Due to the structural complexity of the hypothalamus, however, many basic aspects of its ontogenesis are still mysterious. Nowadays we assist to a renewal of interest spurred in part by the growing realization that prenatal and early postnatal influences on the hypothalamus could entail pathological conditions later in life. Intriguing questions for the future include: do early specification phenomena reflect on adult hypothalamic function and possibly on some kinds of behavior? Can early events like specification, migration or formation of nuclei influence adult hypothalamic function? A change in morphological paradigm, from earlier columnar interpretations to neuromeric ones, is taking place. Concepts long taken for granted start to be challenged in view of advances in developmental and comparative neurobiology, and notably also in the molecular characterization of hypothalamic structures. How should we understand the position of the hypothalamus in relation to other brain regions? Should we bundle it together with the thalamus, a functionally, genetically and developmentally very different structure? Does the classic concept of “diencephalon” make sense, or should the hypothalamus be separated? Does the preoptic area belong to the hypothalamus or the telencephalon? The answer to these questions in the context of recent causal molecular analysis will help to understand hypothalamic evolution and morphogenesis as well as its adult function and connectivity. In this Research Topic we have reviewed the fundamentals of hypothalamic ontogenesis and evolution, summarizing present-day knowledge, taking stock of the latest advances, and anticipating future challenges.

Hypothalamic Pituitary Diseases

Hypothalamic Pituitary Diseases
Author: Felipe F. Casanueva,Ezio Ghigo
Publsiher: Springer
Total Pages: 135
Release: 2019-02-14
Genre: Medical
ISBN: 3319444433

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This book presents the state of the art in the pathophysiology, diagnosis, and therapy of hypothalamic and pituitary disorders. After an introduction devoted to the physiology of the neuroendocrine control of the hypothalamic-pituitary unit, the diverse disorders involving hormonal excess or deficiency are systematically addressed axis by axis. For each disorder, pathophysiology, clinical presentation, and management are discussed in detail. In addition, individual chapters focus on the neuroendocrinology of energy homeostasis and of bone metabolism, metabolic derangement secondary to pituitary dysfunction, and pituitary control of the endocrine pancreas. While the focus of the book is predominantly on pathophysiological and clinical aspects, due attention is also devoted to potential diagnostic and therapeutic innovations. The book is intended as a major reference for endocrinologists and basic and clinical scientists.