Immunological Implications and Molecular Diagnostics of Genitourinary Cancer

Immunological Implications and Molecular Diagnostics of Genitourinary Cancer
Author: Moulay Mustapha Ennaji
Publsiher: Academic Press
Total Pages: 516
Release: 2022-09-15
Genre: Medical
ISBN: 0323854966

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Immunological Implications and Molecular Diagnostics of Genitourinary Cancer updates on recent accomplishments, unifying concepts, and future challenges in the study of tumor-associated immune cells, emphasizing genitourinary cancers. The presence of inflammatory immune cells in human tumors raise a fundamental question: How do cancer cells avoid destruction by immune attack? In principle, tumor development can be controlled by cytotoxic innate and adaptive immune cells, however, as tumors develop from neoplastic tissue to clinically detectable tumors, cancer cells evolve different mechanisms. This book covers research on the immunological implications of genitourinary cancer with a comprehensive view, especially surrounding diagnosis and cellular mechanisms. Discusses the impact of the immune system on the initiation, progression and treatment of cancer Provides insights on the important role of the suppressor genes and oncogenes in genitourinary cancers Shows the advantages of combining clinical issues of urologic cancers with immunological techniques, like immunohistochemistry and immunofluorescence Demonstrates the implications genitourinary cancer has on the human innate immune system

Directory of Pathology Training Programs in the United States and Canada

Directory of Pathology Training Programs in the United States and Canada
Author: Anonim
Publsiher: Unknown
Total Pages: 135
Release: 2008
Genre: Medicine
ISBN: CHI:76992348

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Directory intended to give "medical students and graduate physicians a timely source of detailed information about the many options for pathology training in the United States and Canada." Geographical arrangement. Entries give in narrative such information as programs offered, facilities, community environment, stipends, staff, and application. Training staff index.

Abeloff s Clinical Oncology E Book

Abeloff s Clinical Oncology E Book
Author: Martin D. Abeloff,James O. Armitage,John E. Niederhuber,Michael B. Kastan,W. Gillies McKenna
Publsiher: Elsevier Health Sciences
Total Pages: 2592
Release: 2008-06-30
Genre: Medical
ISBN: 9781437720563

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Carrying on the tradition established by its founding editor, the late Dr. Martin Abeloff, the 4th Edition of this respected reference synthesizes all of the latest oncology knowledge in one practical, clinically focused, easy-to-use volume. It incorporates basic science, pathology, diagnosis, management, outcomes, rehabilitation, and prevention – all in one convenient resource – equipping you to overcome your toughest clinical challenges. What's more, you can access the complete contents of this Expert Consult title online, and tap into its unparalleled guidance wherever and whenever you need it most! Equips you to select the most appropriate tests and imaging studies for diagnosing and staging each type of cancer, and manage your patients most effectively using all of the latest techniques and approaches. Explores all of the latest scientific discoveries' implications for cancer diagnosis and management. Employs a multidisciplinary approach - with contributions from pathologists, radiation oncologists, medical oncologists, and surgical oncologists - for well-rounded perspectives on the problems you face. Offers a user-friendly layout with a consistent chapter format • summary boxes • a full-color design • and more than 1,445 illustrations (1,200 in full color), to make reference easy and efficient. Offers access to the book's complete contents online – fully searchable – from anyplace with an Internet connection. Presents discussions on cutting-edge new topics including nanotechnology, functional imaging, signal transduction inhibitors, hormone modulators, complications of transplantation, and much more. Includes an expanded color art program that highlights key points, illustrates relevant science and clinical problems, and enhances your understanding of complex concepts.

Diagnostic Prognostic and Predictive Biological Markers in Bladder Cancer Illumination of a Vision 2 0

Diagnostic  Prognostic and Predictive Biological Markers in Bladder Cancer     Illumination of a Vision 2 0
Author: Thorsten Ecke,Thomas Otto
Publsiher: MDPI
Total Pages: 240
Release: 2021-02-17
Genre: Medical
ISBN: 9783039436859

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After our successful first Special Issue about bladder cancer, we proceeded with the second issue. Again, many international scientists submitted their newest research results in that extremely interesting field and followed our call for submissions. It is not only the collection and combination of old and new markers that could develop new possibilities, but also the focus on different classifications and sub-classifications that will unveil new ways in diagnostic and therapeutic approaches. It seems that the two established diagnostic tools will still play an important role, but new markers and diagnostics tools will present more detailed and more differentiated possibilities in the treatment of urinary bladder cancer. This second Special Issue is full of scientific results that could provide new ways to help patients with instruments for early diagnostics and with predictive and prognostic markers on their way to finding new and personalized strategies for therapy. The editors thank all of the submitting authors for their efforts and time spent on each manuscript. We hope that this Special Issue will prove useful to research work in bladder cancer in the future. We hope that many talented researchers will use multiple forms of art to improve their professional successes and to ameliorate diagnostics and therapy in bladder cancer.

Invasive Bladder Cancer

Invasive Bladder Cancer
Author: PierFrancesco Bassi,Francesco Pagano
Publsiher: Springer Science & Business Media
Total Pages: 303
Release: 2007-07-29
Genre: Medical
ISBN: 9781846283772

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Invasive bladder tumors affect the muscle wall, and have a propensity to metastasize and spread to other areas of the body, and are more likely to be fatal. This book presents state-of-the-art diagnoses and treatments available for bladder cancer that has metastasised into the body. A thorough review of current practice is presented in a full color volume with more than 40 tables and 50 illustrations. The book offers a comprehensive review of the subject, covering epidemiology, screening, diagnostic factors, surgery, chemotherapy and post-operative monitoring. Most chapters are jointly written by a basic researcher and a clinician.

Management of Muscle Invasive Bladder Cancer

Management of Muscle Invasive Bladder Cancer
Author: Sanchia S. Goonewardene,Karen Ventii,Amit Bahl,Raj Persad,Hanif Motiwala,David Albala
Publsiher: Springer Nature
Total Pages: 590
Release: 2021-02-02
Genre: Medical
ISBN: 9783030579159

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This book provides a systematic review of the management and treatment of this disease. The concise and highly structured chapters feature essential background knowledge and commentary on recent advances within each step of a range of patient pathways. Management of Muscle Invasive Bladder Cancer provides a framework for patients’ care based on the research, as well as practically and clinically oriented guidelines. This book is relevant to trainees and practicing urologists and oncologists, in addition to medical professionals involved in the treatment of bladder cancer.

Workshop on Genitourinary Cancer Immunology

Workshop on Genitourinary Cancer Immunology
Author: William W. Bonney
Publsiher: Unknown
Total Pages: 403
Release: 1978
Genre: Cancer
ISBN: MINN:319510004314018

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Workshop on Genitourinary Cancer Immunology

Workshop on Genitourinary Cancer Immunology
Author: Anonim
Publsiher: Unknown
Total Pages: 403
Release: 1979
Genre: Genitourinary organs
ISBN: PURD:32754081178836

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Molecular Diagnostics

Molecular Diagnostics
Author: George Patrinos,Wilhelm Ansorge
Publsiher: Elsevier
Total Pages: 488
Release: 2005-06-06
Genre: Science
ISBN: 0080473504

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Molecular Diagnostics covers current molecular biological techniques used to identify the underlying molecular defects in inherited disease. Although an increasing number of laboratories, both academic and private are moving in that direction, there are only a few books in the existing literature, and they deal only partly with diagnosis at the molecular level. Each chapter includes the principle and a brief description of the technique, followed by exmples from the authors' own epertise. Contributors are well-known experts in their field, and derive from a variety of disciplines, to ensure breadth and depth of coverage. Examines widely used molecular biology techniques to screen for genetic defects causing inherited disorders Includes state-of-the-art techniques for the detection of the underlying genetic heterogeneity leading to inherited disorders Identification of genetically modified organisms (GMO's) Forensic analysis and every-day issues in a diagnostic laboratory Discusses ethics, genetic counselling and quality management

Bladder Cancer An Issue of Hematology Oncology Clinics of North America E Book

Bladder Cancer  An Issue of Hematology Oncology Clinics of North America  E Book
Author: Guru P. Sonpavde
Publsiher: Elsevier Health Sciences
Total Pages: 240
Release: 2021-05-14
Genre: Medical
ISBN: 9780323764520

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This issue of Hematology/Oncology Clinics, Guest Edited by Dr. Guru P. Sonpavde, is devoted to Bladder Cancer. This issue is one of six selected each year by our series Consulting Editors, George P. Canellos and Edward J. Benz. Topics discussed in this important issue include: Epidemiology of bladder cancer, The molecular biology of bladder cancer and potential implications for therapy, Current therapy for metastatic urothelial carcinoma, Current perioperative therapy for muscle invasive urothelial carcinoma, Current therapy and emerging intravesical agents to treat non-muscle invasive bladder cancer, Diagnosis and staging of bladder and upper tract urothelial cancer, Surgery for bladder and upper tract urothelial cancer, Bladder conserving therapy for muscle invasive bladder cancer: opportunities to incorporate molecular profiling, Emerging immunotherapy for bladder cancer, Emerging targeted therapy for bladder cancer, Real world outcomes of patients with bladder cancer, Preclinical systems to develop bladder cancer therapeutics, Developing precision medicine for bladder cancer, and Future Directions in Bladder Cancer Treatment and Research.

Neoadjuvant Immunotherapy Treatment of Localized Genitourinary Cancers

Neoadjuvant Immunotherapy Treatment of Localized Genitourinary Cancers
Author: Andrea Necchi,Philippe E. Spiess
Publsiher: Springer Nature
Total Pages: 315
Release: 2022-01-03
Genre: Medical
ISBN: 9783030805463

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This book aims to provide readers with a current overview of enrolling trials with immune-checkpoint inhibitors in the preoperative setting of localized bladder cancer, renal cell carcinoma, and prostate cancer. The advent of immunotherapy has revolutionized treatments of genitourinary malignancy and evolved strategies for multidisciplinary management. This book explains neoadjuvant checkpoint inhibitors in localized genitourinary cancers, providing insights into the mechanisms of response and development of resistance of cancer cells to immunotherapy. It debates optimal trial design of preoperative checkpoint inhibitors in GU tumors, including optimal endpoints and the role of pathologic response as a surrogate endpoint of survival. It also illuminates clinical management of patients with organ-confined GU tumors, such as side effect management and perioperative safety, before providing an overview of biomarker use for patient selection across the early-stage GU malignancies. Lastly, the book provides the reader with the most up-to-date data emerging from clinical trials involving immunotherapy in early-stage GU malignancies. Neoadjuvant Immunotherapy Treatment of Localized Genitourinary Cancers: Multidisciplinary Management provides a comprehensive review of the field, serving as a valuable resource for urologists, medical oncologists, pathologists, fellows in urologic oncology, upper-level residents training in urology and medical oncology, as well as pharmacists interested in RCC clinicians.

Role of RNA in Molecular Diagnostics of Cancer

Role of RNA in Molecular Diagnostics of Cancer
Author: Cesar Wong,William Cho,Lawrence Wing Chi Chan
Publsiher: Frontiers Media SA
Total Pages: 135
Release: 2020-07-01
Genre: Electronic Book
ISBN: 9782889638130

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Genitourinary Cancers

Genitourinary Cancers
Author: Siamak Daneshmand,Kevin G. Chan
Publsiher: Springer
Total Pages: 308
Release: 2018-08-31
Genre: Medical
ISBN: 9783319933399

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This book addresses the most pressing current questions in the management of urologic malignancies. The rapid advances in imaging and molecular markers are placed into a clinical context, with explanation of their effects on prognosis and treatment planning. Similarly, progress in immunotherapy is carefully examined, focusing in particular on the role of immune checkpoint inhibitors in both early- and late-stage urologic malignancies. Looking beyond the improvements in minimally invasive techniques for urologic cancers, the impacts of care coordination pathways and enhanced recovery after surgery protocols are reviewed. Readers will also find enlightening discussion of the decision algorithm for the treatment of early-stage, high-grade bladder cancer, taking into account evidence on the most advanced treatment options and the circumstances in which surgery may need to be expedited. The penultimate chapter discusses the Cancer Genome Atlas project for bladder cancer, and the book closes by considering contemporary medical and surgical management of testicular cancer.

Biomedical Index to PHS supported Research

Biomedical Index to PHS supported Research
Author: Anonim
Publsiher: Unknown
Total Pages: 135
Release: 1993
Genre: Medicine
ISBN: STANFORD:36105119624463

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Biomarkers in Urologic Cancer An Issue of Urologic Clinics of North America E Book

Biomarkers in Urologic Cancer  An Issue of Urologic Clinics of North America  E Book
Author: Kevin R. Loughlin
Publsiher: Elsevier Health Sciences
Total Pages: 135
Release: 2016-01-19
Genre: Medical
ISBN: 9780323417198

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The past decade has been marked by the acceleration of our understanding of the molecular biology of cancer. Simultaneously, there have been increasing exigencies to diagnose, treat and follow cancer patients more economically. Biomarkers represent the marriage of science and economics. Biomarkers offer the potential to increase the precision of diagnosis, prognosis, and surveillance of urological malignancies. This issue presents the cutting-edge advances of biomarker technology to urologic oncology.