Inorganic and Organometallic Transition Metal Complexes with Biological Molecules and Living Cells

Inorganic and Organometallic Transition Metal Complexes with Biological Molecules and Living Cells
Author: Kenneth Kam-Wing Lo
Publsiher: Academic Press
Total Pages: 406
Release: 2016-12-30
Genre: Science
ISBN: 9780128038871

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Inorganic and Organometallic Transition Metal Complexes with Biological Molecules and Living Cells provides a complete overview of this important research area that is perfect for both newcomers and expert researchers in the field. Through concise chapters written and edited by esteemed experts, this book brings together a comprehensive treatment of the area previously only available through scattered, lengthy review articles in the literature. Advanced topics of research are covered, with particular focus on recent advances in the biological applications of transition metal complexes, including inorganic medicine, enzyme inhibitors, antiparasital agents, and biological imaging reagents. Geared toward researchers and students who seek an introductory overview of the field, as well as researchers working in advanced areas Focuses on the interactions of inorganic and organometallic transition metal complexes with biological molecules and live cells Foscuses on the fundamentals and their potential therapeutic and diagnostic applications Covers recent biological applications of transition metal complexes, such as anticancer drugs, enzyme inhibitors, bioconjugation agents, chemical biology tools, and bioimaging reagents

Inorganic Chemical Biology

Inorganic Chemical Biology
Author: Gilles Gasser
Publsiher: John Wiley & Sons
Total Pages: 432
Release: 2014-04-14
Genre: Science
ISBN: 9781118684153

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Understanding, identifying and influencing the biologicalsystems are the primary objectives of chemical biology. From this perspective, metal complexes havealways been of great assistance to chemical biologists, for example, in structural identificationand purification of essential biomolecules, for visualizing cellular organelles or to inhibitspecific enzymes. This inorganic side of chemical biology, which continues to receive considerableattention, is referred to as inorganic chemical biology. Inorganic Chemical Biology: Principles, Techniques andApplications provides a comprehensive overview of the current and emerging role of metal complexes inchemical biology. Throughout all of the chapters there is a strong emphasis on fundamentaltheoretical chemistry and experiments that have been carried out in living cells or organisms. Outlooksfor the future applications of metal complexes in chemical biology are also discussed. Topics covered include: • Metal complexes as tools for structural biology • IMAC, AAS, XRF and MS as detection techniques for metals inchemical biology • Cell and organism imaging and probing DNA using metal andmetal carbonyl complexes • Detection of metal ions, anions and small molecules usingmetal complexes • Photo-release of metal ions in living cells • Metal complexes as enzyme inhibitors and catalysts inliving cells Written by a team of international experts, Inorganic ChemicalBiology: Principles, Techniques and Applications is a must-have for bioinorganic,bioorganometallic and medicinal chemists as well as chemical biologists working in both academia and industry.

Smart Polymer Nanocomposites

Smart Polymer Nanocomposites
Author: Showkat Ahmad Bhawani,Anish Khan,Mohammad Jawaid
Publsiher: Woodhead Publishing
Total Pages: 482
Release: 2020-11-28
Genre: Technology & Engineering
ISBN: 9780128204351

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Smart Polymer Nanocomposites: Biomedical and Environmental Applications presents the latest information on smart polymers and their promising application in various fields, including their role in delivery systems for drugs, tissue engineering scaffolds, cell culture sports, bioseparation, and sensors or actuator systems. Features detailed information on the preparation, characterization and applications of smart functional polymer composites Covers a broad range of applications in both the biomedical and environmental engineering fields Chapters are written by authors with diverse background expertise from the faculties of chemistry, engineering and the manufacturing industry

Women in Science Chemistry

Women in Science  Chemistry
Author: Jennifer L. Schaefer,Elisabeth Lojou,Svetlana Ivanova,Silvia Giordani,Qin Li
Publsiher: Frontiers Media SA
Total Pages: 135
Release: 2022-02-08
Genre: Science
ISBN: 9782889742981

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Polymers in Organic Electronics

Polymers in Organic Electronics
Author: Sulaiman Khalifeh
Publsiher: Elsevier
Total Pages: 616
Release: 2020-04-01
Genre: Technology & Engineering
ISBN: 9781927885680

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Polymers in Organic Electronics: Polymer Selection for Electronic, Mechatronic, and Optoelectronic Systems provides readers with vital data, guidelines, and techniques for optimally designing organic electronic systems using novel polymers. The book classifies polymer families, types, complexes, composites, nanocomposites, compounds, and small molecules while also providing an introduction to the fundamental principles of polymers and electronics. Features information on concepts and optimized types of electronics and a classification system of electronic polymers, including piezoelectric and pyroelectric, optoelectronic, mechatronic, organic electronic complexes, and more. The book is designed to help readers select the optimized material for structuring their organic electronic system. Chapters discuss the most common properties of electronic polymers, methods of optimization, and polymeric-structured printed circuit boards. The polymeric structures of optoelectronics and photonics are covered and the book concludes with a chapter emphasizing the importance of polymeric structures for packaging of electronic devices. Provides key identifying details on a range of polymers, micro-polymers, nano-polymers, resins, hydrocarbons, and oligomers Covers the most common electrical, electronic, and optical properties of electronic polymers Describes the underlying theories on the mechanics of polymer conductivity Discusses polymeric structured printed circuit boards, including their rapid prototyping and optimizing their polymeric structures Shows optimization methods for both polymeric structures of organic active electronic components and organic passive electronic components

New Directions in the Modeling of Organometallic Reactions

New Directions in the Modeling of Organometallic Reactions
Author: Agustí Lledós,Gregori Ujaque
Publsiher: Springer Nature
Total Pages: 269
Release: 2020-11-05
Genre: Science
ISBN: 9783030569969

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This book focuses on the computational modeling of organometallic reactivity. In recent years, computational methods, particularly those based on Density Functional Theory (DFT) have been fully incorporated into the toolbox of organometallic chemists’ methods. Nowadays, energy profiles of multistep processes are routinely calculated, and detailed mechanistic pictures of the reactions arise from these calculations. This type of analysis is increasingly performed even by experimentalists themselves. The volume aims to connect established computational organometallics with the more recent theoretical and methodological developments applied to this field. This would allow broadening of the simulation scope toward emergent organometallic areas (as ligand design or photoactivated processes), to narrow the gap between calculations and experiments (microkinetic models) and even to discover new reactions (automated methods). Given the broad interest and extensive application that computational methods have reached within the organometallic community, this new volume will attract the interest of both experimental and computational organometallic chemists.

Nanotheranostics

Nanotheranostics
Author: Mahendra Rai,Bushra Jamil
Publsiher: Springer Nature
Total Pages: 409
Release: 2019-11-22
Genre: Medical
ISBN: 9783030297688

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This book is specifically designed to provide information about various nanocarriers currently developed under the emerging field of nanotheranostics for a sustained, controlled, and targeted co-delivery of diagnostic and therapeutic agents. Diverse theranostic applications of nanotechnology and their limitations are also addressed. It integrates nanobiotechnology with theranostic applications. The combined term nanotheranostics has diverse application particularly in chemotherapy and other infectious diseases.Among other topics addressed are antimicrobial resistance, targeting intra-cellular pathogens, viruses and bacteria, chemotherapy, cancer therapeutics, and inflammatory disorders. This interdisciplinary volume is essential for a diverse group of readers including nanotechnologists, microbiologists, biotechnologists, bioengineering and bioprocess industry.

Advances in Heterocyclic Chemistry

Advances in Heterocyclic Chemistry
Author: Anonim
Publsiher: Academic Press
Total Pages: 437
Release: 2019-03-19
Genre: Science
ISBN: 9780128174746

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Advances in Heterocyclic Chemistry, Volume 129 is the definitive series in the field—one of great importance to organic chemists, polymer chemists and many biological scientists. Because biology and organic chemistry increasingly intersect, the associated nomenclature also is being used more frequently in explanations. Written by established authorities in the field from around the world, this comprehensive, updated release includes chapters on Metal-Catalyzed Direct Arylation of 1,2-Azoles, The Literature of Heterocyclic Chemistry, Part XVII, 2017, Pyrrolo-, Imidazoquinolines and Pyrroloquinazolines with a Bridgehead Nitrogen, Synthesis and Reactions of Arsole, Stibole, and Bismole, Advances in Synthesis and Chemistry of Aziridines, and more. Considered the definitive serial in the field of heterocyclic chemistry Serves as the go-to reference for organic chemists, polymer chemists and many biological scientists Provides the latest comprehensive reviews written by established authorities in the field Combines descriptive synthetic chemistry and mechanistic insight to enhance understanding of how chemistry drives the preparation and useful properties of heterocyclic compounds

Nanohybrids in Environmental Biomedical Applications

Nanohybrids in Environmental   Biomedical Applications
Author: Surender Kumar Sharma
Publsiher: CRC Press
Total Pages: 396
Release: 2019-07-09
Genre: Science
ISBN: 9781351256834

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Heterostructured nanoparticles have the capability for a broad range of novel and enhanced properties, which leads to appealing biomedical and environmental applications. This timely new book addresses the design and preparation of multiphase nanomaterials with desired size, shape, phase composition, and crystallinity, as well as their current applications. It emphasizes key examples to motivate deeper studies, including nanomaterial-based hyperthermia treatment of cancer, nanohybrids for water purification, nanostructures used in the removal or detection of bioagents from waste water, and so on. Features Presents state of the art research on heterostructured nanomaterials, from their synthesis and physiochemical properties to current environmental and biological applications. Includes details on toxicity and risk assessment of multifunctional nanomaterials. Discusses recent developments and utilization in healthcare by leading experts. Introduces the main features of functionalization of nanomaterials in terms of desired size, shape, phase composition, surface functionalization/coating, toxicity, and geometry. Emphasizes practical applications in the environmental and biomedical sectors.

Heterogeneous Catalysis for Sustainable Energy

Heterogeneous Catalysis for Sustainable Energy
Author: Landong Li,Justin S. J. Hargreaves
Publsiher: John Wiley & Sons
Total Pages: 592
Release: 2022-05-03
Genre: Science
ISBN: 9783527815913

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Heterogeneous Catalysis for Sustainable Energy Explore the state-of-the-art in heterogeneous catalysis In Heterogeneous Catalysis for Sustainable Energy, a team of distinguished researchers delivers a comprehensive and cutting-edge treatment of recent advancements in energy-related catalytic reactions and processes in the field of heterogeneous catalysis. The book includes extensive coverage of the hydrogen economy, methane activation, methanol-to-hydrocarbons, carbon dioxide conversion, and biomass conversion. The authors explore different aspects of the technology, like reaction mechanisms, catalyst synthesis, and the commercial status of the reactions. The book also includes: A thorough introduction to the hydrogen economy, including hydrogen production, the reforming of oxygen-containing chemicals, and advances in Fischer-Tropsch Synthesis Comprehensive explorations of methane activation, including steam and dry reforming of methane and methane activation over zeolite catalysts Practical discussions of alkane activation, including cracking of hydrocarbons to light olefins and catalytic dehydrogenation of light alkanes In-depth examinations of zeolite catalysis and carbon dioxide as C1 building block Perfect for catalytic, physical, and surface chemists, Heterogeneous Catalysis for Sustainable Energy also belongs in the libraries of materials scientists with an interest in energy-related reactions and processes in the field of heterogeneous catalysis.

Toxicology of the Gastrointestinal Tract Second Edition

Toxicology of the Gastrointestinal Tract  Second Edition
Author: Shayne Cox Gad
Publsiher: CRC Press
Total Pages: 476
Release: 2018-10-26
Genre: Medical
ISBN: 9780429781445

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The gastrointestinal tract is the most important of the three major routes of entry (and clearance) of xenobiotics and biologic entities into the bodies of mammals. As such, it is also the major route for administration of pharmaceuticals to humans. Gastrointestinal Toxicology, Second Edition describes the mechanism for entry and clearance of xenobiotics, as well as the barriers, immunologic and metabolic issues, and functions present in the GI tract. Appearing in this volume are also considerations of the microbiome and its actions and influence on the function of the GI tract and on the toxicity and pharmacodynamics of ingested substances (including nutrients, toxins, and therapeutics). These fifteen chapters written by experienced experts in the field address methods to evaluate GI function; specifics of GI function and toxicity assessment in canines and minipigs; classes of compounds with their toxicity; species differences; and the toxicity (and promise) of nanoparticles. Those needing to understand the structure, function, and methods of studying the GI tract will find this volume a singular source of reference.

Advances in Organometallic Chemistry

Advances in Organometallic Chemistry
Author: Pedro J. Perez
Publsiher: Academic Press
Total Pages: 480
Release: 2020-06-06
Genre: Science
ISBN: 9780128206935

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Advances in Organometallic Chemistry, Volume 74, the latest release in this longstanding serial, is known for its comprehensive coverage of topics in organometallic synthesis, reactions, mechanisms, homogeneous catalysis, and more. It is ideal for a wide range of researchers involved in organometallic chemistry, with this updated release including chapters on Metal dendrimers used in biomedical applications, Sigma-bond activation reactions induced by unsaturated osmium (IV) complexes with bulky phosphines, Base metal pincer complexes, and more. Contains contributions from leading authorities in the field of organometallic chemistry Covers topics in organometallic synthesis, reactions, mechanisms, homogeneous catalysis, and more Informs and updates readers on the latest developments in the field Carefully edited to provide easy-to-read material

Fluorescent Materials for Cell Imaging

Fluorescent Materials for Cell Imaging
Author: Fu-Gen Wu
Publsiher: Springer Nature
Total Pages: 247
Release: 2020-10-26
Genre: Medical
ISBN: 9789811550621

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This book focuses on the latest fluorescent materials for cell imaging. Cell imaging is a widely used basic technique that helps scientists gain a better understanding of biological functions through studies of cellular structure and dynamics. In the past decades, the development of a variety of new fluorescent materials has significantly extended the applications of cellular imaging techniques. This book presents recently developed fluorescent materials, including semiconductor quantum dots, carbon dots, silicon nanoparticles, metal nanoclusters, upconversion nanoparticles, conjugated polymers/polymer dots, aggregation-induced emission (AIE) probes, and coordination compounds, used for various cellular imaging purposes. It will appeal to cell biologists and other researchers in academia, industry and clinical settings who are interested in the technical development and advanced applications of fluorescence imaging in cells, tissues and organisms to explore the mechanisms of biological functions and diseases.

The Future of Pharmaceutical Product Development and Research

The Future of Pharmaceutical Product Development and Research
Author: Anonim
Publsiher: Academic Press
Total Pages: 976
Release: 2020-09-02
Genre: Medical
ISBN: 9780128144558

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The Future of Pharmaceutical Product Development and Research examines the latest developments in the pharmaceutical sciences, also highlighting key developments, research and future opportunities. Written by experts in the field, this volume in the Advances in Pharmaceutical Product Development and Research series deepens our understanding of the product development phase of drug discovery and drug development. Each chapter covers fundamental principles, advanced methodologies and technologies employed by pharmaceutical scientists, researchers and the pharmaceutical industry. The book focuses on excipients, radiopharmaceuticals, and how manufacturing should be conducted in an environment that follows Good Manufacturing Practice (GMP) guidelines. Researchers and students will find this book to be a comprehensive resource for those working in, and studying, pharmaceuticals, cosmetics, biotechnology, foods and related industries. Provides an overview of practical information for clinical trials Outlines how to ensure an environment that follows Good Manufacturing Practice (GMP) Examines recent developments and suggests future directions for drug production methods and techniques

The Chemistry and Biology of Nitroxyl HNO

The Chemistry and Biology of Nitroxyl  HNO
Author: Fabio Doctorovich,Patrick J. Farmer,Marcelo A. Marti
Publsiher: Elsevier
Total Pages: 424
Release: 2016-09-01
Genre: Science
ISBN: 9780128011645

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The Chemistry and Biology of Nitroxyl (HNO) provides first-of-its-kind coverage of the intriguing biologically active molecule called nitroxyl, or azanone per IUPAC nomenclature, which has been traditionally elusive due to its intrinsically high reactivity. This useful resource provides the scientific basis to understand the chemistry, biology, and technical aspects needed to deal with HNO. Building on two decades of nitric oxide and nitroxyl research, the editors and authors have created an indispensable guide for investigators across a wide variety of areas of chemistry (inorganic, organic, organometallic, biochemistry, physical, and analytical); biology (molecular, cellular, physiological, and enzymology); pharmacy; and medicine. This book begins by exploring the unique molecule’s structure and reactivity, including important reactions with small molecules, thiols, porphyrins, and key proteins, before discussing chemical and biological sources of nitroxyl. Advanced chapters discuss methods for both trapping and detecting nitroxyl by spectroscopy, electrochemistry, and fluorescent inorganic cellular probing. Expanding on the compound’s foundational chemistry, this book then explores its molecular physiology to offer insight into its biological implications, pharmacological effects, and practical issues. Presents the first book on HNO (nitroxyl or azanone), an increasingly important molecule in biochemistry and pharmaceutical research Provides a valuable coverage of HNO’s chemical structure and significant reactions, including practical guidance on working with this highly reactive molecule Contains high quality content from recognized experts in both industry and academia