Matlab in Bioscience and Biotechnology

Matlab   in Bioscience and Biotechnology
Author: Leonid Burstein
Publsiher: Elsevier
Total Pages: 268
Release: 2011-06-05
Genre: Science
ISBN: 9781908818034

Download Matlab in Bioscience and Biotechnology Book in PDF, Epub and Kindle

MATLAB® in bioscience and biotechnology presents an introductory Matlab course oriented towards various collaborative areas of biotechnology and bioscience. It concentrates on Matlab fundamentals and gives examples of its application to a wide range of current bioengineering problems in computational biology, molecular biology, bio-kinetics, biomedicine, bioinformatics, and biotechnology. In the last decade Matlab has been presented to students as the first computer program they learn. Consequently, many non-programmer students, engineers and scientists have come to regard it as user-friendly and highly convenient in solving their specific problems. Numerous books are available on programming in Matlab for engineers in general, irrespective of their specialization, or for those specializing in some specific area, but none have been designed especially for such a wide, interdisciplinary, and topical area as bioengineering. Thus, in this book, Matlab is presented with examples and applications to various school-level and advanced bioengineering problems - from growing populations of microorganisms and population dynamics, reaction kinetics and reagent concentrations, predator-prey models, mass-transfer and flow problems, to sequence analysis and sequence statistics. This is the first book intended as a manual introducing biologists and other biotechnology engineers to work with Matlab It is suitable for beginners and inexperienced users; however, applications of Matlab to advanced problems such as the Monte Carlo method, curve fitting, and reliable machine diagnostics make the book relevant to university teachers as well The book is different in that it assumes a modest mathematical background for the reader and introduces the mathematical or technical concepts with a somewhat traditional approach; Matlab is then used as a tool for subsequent computer solution

Bioprocess Engineering

Bioprocess Engineering
Author: Kim Gail Clarke
Publsiher: Elsevier
Total Pages: 266
Release: 2013-10-31
Genre: Science
ISBN: 9781782421689

Download Bioprocess Engineering Book in PDF, Epub and Kindle

Biotechnology is an expansive field incorporating expertise in both the life science and engineering disciplines. In biotechnology, the scientist is concerned with developing the most favourable biocatalysts, while the engineer is directed towards process performance, defining conditions and strategies that will maximize the production potential of the biocatalyst. Increasingly, the synergistic effect of the contributions of engineering and life sciences is recognised as key to the translation of new bioproducts from the laboratory bench to commercial bioprocess. Fundamental to the successful realization of the bioprocess is a need for process engineers and life scientists competent in evaluating biological systems from a cross-disciplinary viewpoint. Bioprocess engineering aims to generate core competencies through an understanding of the complementary biotechnology disciplines and their interdependence, and an appreciation of the challenges associated with the application of engineering principles in a life science context. Initial chapters focus on the microbiology, biochemistry and molecular biology that underpin biocatalyst potential for product accumulation. The following chapters develop kinetic and mass transfer principles that quantify optimum process performance and scale up. The text is wide in scope, relating to bioprocesses using bacterial, fungal and enzymic biocatalysts, batch, fed-batch and continuous strategies and free and immobilised configurations. Details the application of chemical engineering principles for the development, design, operation and scale up of bioprocesses Details the knowledge in microbiology, biochemistry and molecular biology relevant to bioprocess design, operation and scale up Discusses the significance of these life sciences in defining optimum bioprocess performance

Primary MATLAB for Life Sciences Guide for Beginners

Primary MATLAB   for Life Sciences  Guide for Beginners
Author: Leonid Burstein
Publsiher: Bentham Science Publishers
Total Pages: 279
Release: 2013-12-07
Genre: Computers
ISBN: 9781608058044

Download Primary MATLAB for Life Sciences Guide for Beginners Book in PDF, Epub and Kindle

This e-book provides readers a short introductory MATLAB® course oriented towards various collaborative areas of biotechnology and bioscience. The text concentrates on MATLAB® fundamentals and gives examples of its application for various problems in computational biology, molecular biology, biokinetics, biomedicine, bioinformatics, and biotechnology. MATLAB® is presented with examples and applications to various school-level and advanced life science / bioengineering problems - from growing populations of microorganisms and population dynamics, reaction kinetics and reagent concentrations, predator-prey models, to data fitting and time series analysis. The book is divided into 6 chapters containing material carefully selected and tailored to teaching several groups of biotechnology students. The topics are presented in a manner that allows readers to proceed sequentially on the strength of the preceding material. Primary MATLAB® for Life Sciences: A Guide for Beginners is essentially a concise and comprehensive text that provides an easy grasp and to-the-point access to the MATLAB® tool to the community of life sciences and bioengneering undergraduates and specialists.

Matlab in Quality Assurance Sciences

Matlab   in Quality Assurance Sciences
Author: Leonid Burstein
Publsiher: Elsevier
Total Pages: 264
Release: 2015-02-12
Genre: Business & Economics
ISBN: 9780857094889

Download Matlab in Quality Assurance Sciences Book in PDF, Epub and Kindle

MATLAB® in Quality Assurance Sciences fills a gap in the highly topical field of quality assurance (QA). It is a compact guide for students, engineers, and scientists in this field. It concentrates on MATLAB® fundamentals with examples of application to a wide range of current problems from general, nano and bio-technology, and statistical control, to medicine and industrial management. Examples cover both the school and advanced level; comprising calculations of total quality management, six sigma, time series, process improvement, metrology, quality control, human factors in quality assurance, measurement and testing techniques, quality project and function management, and customer satisfaction. This book covers key topics, including: the basics of software with examples; graphics and representations; numerical computation, scripts and functions for QA calculations; ODE and PDEPE solvers applied to QA problems; curve fitting and time series tool interfaces in calculations of quality; and statistics calculations applied to quality testing. Includes MATLAB® fundamentals, matrices, arrays, general graphics and specialized plots in quality assurance problems, script files, ordinary and partial differential equations Gives calculation of six sigma, total quality management, time series forecasting, reliability, process improvement, metrology, quality control and assurance, measurement and testing techniques Provides tools for graphical presentation, basic and special statistics and testing, ordinary and partial differential solvers, and fitting tools

Primary Matlab for Life Sciences

Primary Matlab   for Life Sciences
Author: Leonid Burstein
Publsiher: Unknown
Total Pages: 135
Release: 2022
Genre: Electronic book
ISBN: OCLC:1066598215

Download Primary Matlab for Life Sciences Book in PDF, Epub and Kindle

Annotation This e-book provides readers a short introductory MATLAB® course oriented towards various collaborative areas of biotechnology and bioscience. the text concentrates on MATLAB® fundamentals and gives examples of its application for various problems in computational biology, molecular biology, biokinetics, biomedicine, bioinformatics, and biotechnology. MATLAB® is presented with examples and applications to various school-level and advanced life science / bioengineering problems - from growing populations of microorganisms and population dynamics, reaction kinetics and reagent concentrations, predator-prey models, to data fitting and time series analysis. The book is divided into 6 chapters containing material carefully selected and tailored to teaching several groups of biotechnology students. the topics are presented in a manner that allows readers to proceed sequentially on the strength of the preceding material. Primary MATLAB® for Life Sciences: a Guide for Beginners is essentially a concise and comprehensive text that provides an easy grasp and to-the-point access to the MATLAB® tool to the community of life sciences and bioengneering undergraduates and specialists.

Primary MATLAB for Life Sciences

Primary MATLAB   for Life Sciences
Author: Leonid Burstein
Publsiher: Unknown
Total Pages: 279
Release: 2013-12-07
Genre: Computers
ISBN: 1608058050

Download Primary MATLAB for Life Sciences Book in PDF, Epub and Kindle

This e-book provides readers a short introductory MATLAB� course oriented towards various collaborative areas of biotechnology and bioscience. The text concentrates on MATLAB� fundamentals and gives examples of its application for various problems in comp

From Plant Genomics to Plant Biotechnology

From Plant Genomics to Plant Biotechnology
Author: Palmiro Poltronieri,Natalija Burbulis,Corrado Fogher
Publsiher: Elsevier
Total Pages: 274
Release: 2013-08-31
Genre: Science
ISBN: 9781908818478

Download From Plant Genomics to Plant Biotechnology Book in PDF, Epub and Kindle

With the appearance of methods for the sequencing of genomes and less expensive next generation sequencing methods, we face rapid advancements of the -omics technologies and plant biology studies: reverse and forward genetics, functional genomics, transcriptomics, proteomics, metabolomics, the movement at distance of effectors and structural biology. From plant genomics to plant biotechnology reviews the recent advancements in the post-genomic era, discussing how different varieties respond to abiotic and biotic stresses, understanding the epigenetic control and epigenetic memory, the roles of non-coding RNAs, applicative uses of RNA silencing and RNA interference in plant physiology and in experimental transgenics and plants modified to specific aims. In the forthcoming years these advancements will support the production of plant varieties better suited to resist biotic and abiotic stresses, for food and non-food applications. This book covers these issues, showing how such technologies are influencing the plant field in sectors such as the selection of plant varieties and plant breeding, selection of optimum agronomic traits, stress-resistant varieties, improvement of plant fitness, improving crop yield, and non-food applications in the knowledge based bio-economy. Discusses a broad range of applications: the examples originate from a variety of sectors (including in field studies, breeding, RNA regulation, pharmaceuticals and biotech) and a variety of scientific areas (such as bioinformatics, -omics sciences, epigenetics, and the agro-industry) Provides a unique perspective on work normally performed 'behind closed doors'. As such, it presents an opportunity for those within the field to learn from each other, and for those on the 'outside' to see how different groups have approached key problems Highlights the criteria used to compare and assess different approaches to solving problems. Shows the thinking process, practical limitations and any other considerations, aiding in the understanding of a deeper approach

A Biotech Manager s Handbook

A Biotech Manager s Handbook
Author: M O'Neill,M M Hopkins
Publsiher: Elsevier
Total Pages: 414
Release: 2012-05-02
Genre: Science
ISBN: 9781908818157

Download A Biotech Manager s Handbook Book in PDF, Epub and Kindle

A biotech manager's handbook lays out - in a simple, straightforward manner - for the manager or would-be entrepreneur the basic principles of running a biotech company. Most managers in biotechnology companies are working in their first company or in their first managerial role. Their expertise and experience in the scientific part of the work can be taken as a given but there is a whole range of other skills to be learned and areas of expertise to come to terms with. Small companies do not have big budgets to hire people or time to become an expert in so many areas. The book starts by outlining the state of the biopharmaceutical industry and goes on to explain the importance of planning (no matter what the size of the company). Succeeding chapters deal with the basics of intellectual property, perspectives from a university technology transfer office and how to raise some initial funding from an investor and entrepreneur. No other 'how to' manual exists for this sector Written by a range of expert professionals in each area, all in one book Is the only 'bench to bedside' book covering the whole spectrum of development

The Funding of Biopharmaceutical Research and Development

The Funding of Biopharmaceutical Research and Development
Author: David R Williams
Publsiher: Elsevier
Total Pages: 284
Release: 2013-10-31
Genre: Medical
ISBN: 9781908818386

Download The Funding of Biopharmaceutical Research and Development Book in PDF, Epub and Kindle

The funding of biopharmaceutical research and development provides a comprehensive critical review of the funding of research and development (R&D) in the human biopharmaceutical market sector. It addresses both private and public funding sources available in the US and internationally. The biopharmaceutical market is among the most research-intensive market sectors globally. Clinical researchers face a multitude of public and private funding options with respect to bringing their idea or innovation to market. These funding options are continually changing and complex, and are expected to decrease in the near future. A lack of understanding of the scale, scope, and inner workings of the funding aspects of R&D can, at times, act as a barrier for all involved, and can slow down or even eliminate the R&D process. The book lessens these barriers by describing the theoretical underpinnings, present practice, and trends in R&D funding in this market sector, both in the US and internationally. This includes a review and discussion of public-private partnership activity and their inner-workings, noting the complementary relationship between public and private funding. The book also contains an overview of the inner-workings of strategic alliance activity, including the advantages and disadvantages for each party. It goes on to provide an outline of venture capital activity, detailing the methods by which venture capital firms raise capital and are organized, a description of the venture capital-entrepreneur arrangement, and the effects of this arrangement. The book also presents an overview of the IPO process and the various fates of firms going public. Presents a comprehensive view of the funding issues of R&D in this market sector, adopting a theory-to-practice approach A comprehensive and analytical review of the biopharmaceutical R&D literature and practice An overview of the various and competing/complementary theories of the firm and valuation methods as they apply to biopharmaceutical R&D

Contract Research and Manufacturing Services CRAMS in India

Contract Research and Manufacturing Services  CRAMS  in India
Author: Milind Antani,Gowree Gokhale
Publsiher: Elsevier
Total Pages: 248
Release: 2012-10-31
Genre: Medical
ISBN: 9781908818164

Download Contract Research and Manufacturing Services CRAMS in India Book in PDF, Epub and Kindle

The field of contract research and manufacturing broadly encompasses those services in the pharmaceutical and biotechnology sectors that require extensive research and development and large-scale manufacturing facilities. The field has great potential for growth in the Indian outsourcing industry, which is world-renowned for its provision of cheap and highly-skilled services. Contract research and manufacturing services (CRAMS) in India provides a detailed account of the current scenario in India and the advantages that the Indian outsourcing industry can offer in the field of CRAMS. Following an overview of the services and their emergence in India, chapters in the book begin by discussing the legal and regulatory scenario and major concerns and issues. In the latter part of the book, topics covered include service agreements, dispute resolution and contract negotiations, followed by a discussion of the outlook for CRAMS in India and some concluding remarks. Several appendices are included, offering a list of major players in the field and various forms for use in licence applications. Simple and accessible presentation using tables, charts and diagrams Practical tips from leading practitioners Inclusion of relevant case laws and other legal considerations

NMR Metabolomics in Cancer Research

NMR Metabolomics in Cancer Research
Author: Miroslava Čuperlović-Culf
Publsiher: Elsevier
Total Pages: 446
Release: 2012-12-17
Genre: Medical
ISBN: 9781908818263

Download NMR Metabolomics in Cancer Research Book in PDF, Epub and Kindle

The application of nuclear magnetic resonance (NMR) metabolomics in cancer research requires an understanding of the many possibilities that NMR metabolomics can offer, as well as of the specific characteristics of the cancer metabolic phenotype and the open questions in cancer research. NMR metabolomics in cancer research presents a detailed account of the NMR spectroscopy methods applied to metabolomics mixture analysis along with a discussion of their advantages and disadvantages. Following an overview of the potential use of NMR metabolomics in cancer research, the book begins with an examination of the cancer metabolic phenotype and experimental methodology, before moving on to cover data pre-processing and data analysis. Chapters in the latter part of the book look at dynamic metabolic profiling, biomarker discovery, and the application of NMR metabolomics for different types of cancer, before a concluding chapter discusses future perspectives in the field. Focused description of NMR spectroscopy needed by cancer biologists who are starting to use metabolomics Current overview of knowledge related to the cancer metabolic phenotype from the perspective of metabolomics applications Information about the best practices in NMR metabolomics experimentation and data preprocessing as applied to different sample types

Nanoparticulate Drug Delivery

Nanoparticulate Drug Delivery
Author: Vandana Patravale,Prajakta Dandekar,Ratnesh Jain
Publsiher: Elsevier
Total Pages: 244
Release: 2012-10-31
Genre: Medical
ISBN: 9781908818195

Download Nanoparticulate Drug Delivery Book in PDF, Epub and Kindle

Nanotechnology-based therapeutics, operating at scales of billionths of a metre, have great potential for future expansion in altering the scale and methods of drug delivery. The availability of these novel formulations to once-inaccessible areas of the body has greatly expanded the therapeutic window of existing drug molecules. Nanoparticulate drug delivery highlights and examines the transition of nanoparticulate drug delivery systems from the laboratory into a commercially viable sector. The first chapters of the book provide an overview of the use and characterization of nanoparticulate systems as drug carriers, including the assessment of their morphology, sterility and potential toxicity. In the latter part of the book, chapters cover nanotoxicology, regulatory aspect and clinical trials, ending with an overview of several case studies and a look towards future developments. Discusses the issues surrounding nanoparticulate products, based on personal experience of their formulation Provides an overview of new application areas, including RNA interference Outlines the pros and cons of nanoparticulate products, and discusses how these may influence their route into the commercial sector

Computer Aided Applications in Pharmaceutical Technology

Computer Aided Applications in Pharmaceutical Technology
Author: Jelena Djuris
Publsiher: Elsevier
Total Pages: 300
Release: 2013-04-10
Genre: Medical
ISBN: 9781908818324

Download Computer Aided Applications in Pharmaceutical Technology Book in PDF, Epub and Kindle

Research and development in the pharmaceutical industry is a time-consuming and expensive process, making it difficult for newly developed drugs to be formulated into commercially available products. Both formulation and process development can be optimized by means of statistically organized experiments, artificial intelligence and other computational methods. Simultaneous development and investigation of pharmaceutical products and processes enables application of quality by design concept that is being promoted by the regulatory authorities worldwide. Computer-aided applications in pharmaceutical technology covers the fundamentals of experimental design application and interpretation in pharmaceutical technology, chemometric methods with emphasis of their application in process control, neural computing (artificial neural networks, fuzzy logic and decision trees, evolutionary computing and genetic algorithms, self-organizing maps), computer-aided biopharmaceutical characterization as well as application of computational fluid dynamics in pharmaceutical technology. All of these techniques are essential tools for successful building of quality into pharmaceutical products and processes from the early stage of their development to selection of the optimal ones. In addition to theoretical aspects of various methods, the book provides numerous examples of their application in the field of pharmaceutical technology. A comprehensive review of the current state of the art on various computer aided applications in pharmaceutical technology Case studies are presented in order to facilitate understanding of various concepts in computer-aided applications

Formulation tools for Pharmaceutical Development

Formulation tools for Pharmaceutical Development
Author: J E Aguilar
Publsiher: Elsevier
Total Pages: 304
Release: 2013-09-30
Genre: Medical
ISBN: 9781908818508

Download Formulation tools for Pharmaceutical Development Book in PDF, Epub and Kindle

A range of new and innovative tools used for preformulation and formulation of medicines help optimize pharmaceutical development projects. Such tools also assist with the performance evaluation of the pharmaceutical process, allowing any potential gaps to be identified. These tools can be applied in both basic research and industrial environment. Formulation tools for pharmaceutical development considers these key research and industrial tools. Nine chapters by leading contributors cover: Artificial neural networks technology to model, understand, and optimize drug formulations; ME_expert 2.0: a heuristic decision support system for microemulsions formulation development; Expert system for the development and formulation of push-pull osmotic pump tablets containing poorly water-soluble drugs; SeDeM Diagram: an expert system for preformulation, characterization and optimization of tables obtained by direct compression; New SeDeM-ODT expert system: an expert system for formulation of orodispersible tablets obtained by direct compression; and 3D-cellular automata in computer-aided design of pharmaceutical formulations: mathematical concept and F-CAD software. Coverage of artificial intelligence tools, new expert systems, understanding of pharmaceutical processes, robust development of medicines, and new ways to develop medicines Development of drugs and medicines using mathematical tools Compilation of expert system developed around the world

An Introduction to Pharmaceutical Sciences

An Introduction to Pharmaceutical Sciences
Author: Jiben Roy
Publsiher: Elsevier
Total Pages: 446
Release: 2011-07-25
Genre: Medical
ISBN: 9781908818041

Download An Introduction to Pharmaceutical Sciences Book in PDF, Epub and Kindle

This textbook is written as a unified approach to various topics, ranging from drug discovery to manufacturing, techniques and technology, regulation and marketing. The key theme of the book is pharmaceuticals - what every student of pharmaceutical sciences should know: from the active pharmaceutical ingredients to the preparation of various dosage forms along with the relevant chemistry, this book makes pharmaceuticals relevant to undergraduate students of pharmacy and pharmaceutical sciences. This book explains how a particular drug was discovered and then converted from lab-scale to manufacturing scale, to the market. It explains the motivation for drug discovery, the reaction chemistry involved, experimental difficulties, various dosage forms and the reasoning behind them, mechanism of action, quality assurance and role of regulatory agencies. After having a course based on this book, the student will be able to understand: 1) the career prospects in the pharmaceutical industry, 2) the need for interdisciplinary teamwork in science, 3) the techniques and technology involved in making pharmaceuticals starting from bulk drugs, and 4) different dosage forms and critical factors in the development of pharmaceutical formulations in relation to the principles of chemistry. A few blockbuster drugs including atorvastatin, sildanefil, ranitidine, ciprofloxacin, amoxicillin, and the longest serving drugs such as aspirin and paracetamol are discussed in detail. Finally, the book also covers the important current pharmaceutical issues like quality control, safety, counterfeiting and abuse of drugs, and future prospects for pharmaceutical industry. Unified approach explaining drug discovery, bulk drug manufacturing, formulation of dosage forms, with pharmacological and therapeutic actions Manufacturing processes of representative active pharmaceutical ingredients and their chemistry plus formulation of dosage forms presented in this book are based on actual industrial processes Covers many aspects relevant to students of the pharmaceutical sciences or newly employed pharmaceutical researchers/employees. It contains summary information about regulatory agencies of different countries