Methods in Biomedical Informatics

Methods in Biomedical Informatics
Author: Indra Neil Sarkar
Publsiher: Academic Press
Total Pages: 592
Release: 2013-09-03
Genre: Computers
ISBN: 9780124016842

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Beginning with a survey of fundamental concepts associated with data integration, knowledge representation, and hypothesis generation from heterogeneous data sets, Methods in Biomedical Informatics provides a practical survey of methodologies used in biological, clinical, and public health contexts. These concepts provide the foundation for more advanced topics like information retrieval, natural language processing, Bayesian modeling, and learning classifier systems. The survey of topics then concludes with an exposition of essential methods associated with engineering, personalized medicine, and linking of genomic and clinical data. Within an overall context of the scientific method, Methods in Biomedical Informatics provides a practical coverage of topics that is specifically designed for: (1) domain experts seeking an understanding of biomedical informatics approaches for addressing specific methodological needs; or (2) biomedical informaticians seeking an approachable overview of methodologies that can be used in scenarios germane to biomedical research. Contributors represent leading biomedical informatics experts: individuals who have demonstrated effective use of biomedical informatics methodologies in the real-world, high-quality biomedical applications Material is presented as a balance between foundational coverage of core topics in biomedical informatics with practical "in-the-trenches" scenarios. Contains appendices that function as primers on: (1) Unix; (2) Ruby; (3) Databases; and (4) Web Services.

Evaluation Methods in Medical Informatics

Evaluation Methods in Medical Informatics
Author: Charles P. Friedman,Jeremy C. Wyatt
Publsiher: Springer Science & Business Media
Total Pages: 311
Release: 2013-03-14
Genre: Medical
ISBN: 9781475726855

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As director of a training program in medical informatics, I have found that one of the most frequent inquiries from graduate students is, "Although I am happy with my research focus and the work I have done, how can I design and carry out a practical evaluation that proves the value of my contribution?" Informatics is a multifaceted, interdisciplinary field with research that ranges from theoretical developments to projects that are highly applied and intended for near-term use in clinical settings. The implications of "proving" a research claim accordingly vary greatly depending on the details of an individual student's goals and thesis state ment. Furthermore, the dissertation work leading up to an evaluation plan is often so time-consuming and arduous that attempting the "perfect" evaluation is fre quently seen as impractical or as diverting students from central programming or implementation issues that are their primary areas of interest. They often ask what compromises are possible so they can provide persuasive data in support of their claims without adding another two to three years to their graduate student life. Our students clearly needed help in dealing more effectively with such dilem mas, and it was therefore fortuitous when, in the autumn of 1991, we welcomed two superb visiting professors to our laboratories.

Methods in Medical Informatics

Methods in Medical Informatics
Author: Jules J. Berman
Publsiher: CRC Press
Total Pages: 413
Release: 2010-09-22
Genre: Mathematics
ISBN: 1439841845

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Too often, healthcare workers are led to believe that medical informatics is a complex field that can only be mastered by teams of professional programmers. This is simply not the case. With just a few dozen simple algorithms, easily implemented with open source programming languages, you can fully utilize the medical information contained in clini

Deep Learning Techniques for Biomedical and Health Informatics

Deep Learning Techniques for Biomedical and Health Informatics
Author: Basant Agarwal,Valentina Emilia Balas,Lakhmi C. Jain,Ramesh Chandra Poonia,Manisha Sharma
Publsiher: Academic Press
Total Pages: 367
Release: 2020-01-14
Genre: Science
ISBN: 9780128190623

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Deep Learning Techniques for Biomedical and Health Informatics provides readers with the state-of-the-art in deep learning-based methods for biomedical and health informatics. The book covers not only the best-performing methods, it also presents implementation methods. The book includes all the prerequisite methodologies in each chapter so that new researchers and practitioners will find it very useful. Chapters go from basic methodology to advanced methods, including detailed descriptions of proposed approaches and comprehensive critical discussions on experimental results and how they are applied to Biomedical Engineering, Electronic Health Records, and medical image processing. Examines a wide range of Deep Learning applications for Biomedical Engineering and Health Informatics, including Deep Learning for drug discovery, clinical decision support systems, disease diagnosis, prediction and monitoring Discusses Deep Learning applied to Electronic Health Records (EHR), including health data structures and management, deep patient similarity learning, natural language processing, and how to improve clinical decision-making Provides detailed coverage of Deep Learning for medical image processing, including optimizing medical big data, brain image analysis, brain tumor segmentation in MRI imaging, and the future of biomedical image analysis

Methodology for Assessment of Medical IT based Systems

Methodology for Assessment of Medical IT based Systems
Author: Jytte Brender
Publsiher: IOS Press
Total Pages: 312
Release: 1997
Genre: Medical
ISBN: 9051993374

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10.2 The Role and Contents of the URD in an Assessment Perspective -- 10.3 The Enterprise Model -- 10.4 The Normative Model -- 10.5 Assessment of the User Requirements Document -- 10.6 Discussion -- 11 Dynamic Aspects of the Assessment Methodology -- 11.1 Dynamic Aspects of IT-Development and Application -- 11.2 Adaptation of Frames of Reference for Assessment Activities -- 11.3 Feed-forward Loops -- 11.4 Support of Context Dependent Assessment -- 11.5 Conclusion -- 12 The Dynamic Assessment Methodology -- 12.1 Philosophy -- 12.2 Application Area -- 12.3 Operationalisation of the Methodology -- 12.4 Applicable Methods -- 12.5 Summary -- 13 Discussion -- 13.1 Discussion of Fulfilment of Objective for the 4th Goal -- 13.2 Conclusion of the Study -- References -- Appendix 1: Vocabulary -- Appendix 2: Abbreviations & Acronyms -- Appendix 3: KAVAS's & ISAR's Evaluation Methodology -- Appendix 4: Methodology for Assessment of Functionality -- Appendix 5: Experimental Observations: Functionality Assessment -- Appendix 6: Experimental Observations: LFA -- Appendix 7: Causal Analysis of Experimental Observations -- Appendix 8: Method for Elicitation of a Strategy -- Appendix 9: Selected References regarding Assessment Methods

Biomedical Informatics

Biomedical Informatics
Author: Edward H. Shortliffe,James J. Cimino
Publsiher: Springer Science & Business Media
Total Pages: 965
Release: 2013-12-02
Genre: Medical
ISBN: 9781447144748

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The practice of modern medicine and biomedical research requires sophisticated information technologies with which to manage patient information, plan diagnostic procedures, interpret laboratory results, and carry out investigations. Biomedical Informatics provides both a conceptual framework and a practical inspiration for this swiftly emerging scientific discipline at the intersection of computer science, decision science, information science, cognitive science, and biomedicine. Now revised and in its third edition, this text meets the growing demand by practitioners, researchers, and students for a comprehensive introduction to key topics in the field. Authored by leaders in medical informatics and extensively tested in their courses, the chapters in this volume constitute an effective textbook for students of medical informatics and its areas of application. The book is also a useful reference work for individual readers needing to understand the role that computers can play in the provision of clinical services and the pursuit of biological questions. The volume is organized so as first to explain basic concepts and then to illustrate them with specific systems and technologies.

Principles of Biomedical Informatics

Principles of Biomedical Informatics
Author: Ira J. Kalet, PhD
Publsiher: Academic Press
Total Pages: 708
Release: 2013-09-26
Genre: Computers
ISBN: 9780123914620

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This second edition of a pioneering technical work in biomedical informatics provides a very readable treatment of the deep computational ideas at the foundation of the field. Principles of Biomedical Informatics, 2nd Edition is radically reorganized to make it especially useable as a textbook for courses that move beyond the standard introductory material. It includes exercises at the end of each chapter, ideas for student projects, and a number of new topics, such as: • tree structured data, interval trees, and time-oriented medical data and their use • On Line Application Processing (OLAP), an old database idea that is only recently coming of age and finding surprising importance in biomedical informatics • a discussion of nursing knowledge and an example of encoding nursing advice in a rule-based system • X-ray physics and algorithms for cross-sectional medical image reconstruction, recognizing that this area was one of the most central to the origin of biomedical computing • an introduction to Markov processes, and • an outline of the elements of a hospital IT security program, focusing on fundamental ideas rather than specifics of system vulnerabilities or specific technologies. It is simultaneously a unified description of the core research concept areas of biomedical data and knowledge representation, biomedical information access, biomedical decision-making, and information and technology use in biomedical contexts, and a pre-eminent teaching reference for the growing number of healthcare and computing professionals embracing computation in health-related fields. As in the first edition, it includes many worked example programs in Common LISP, the most powerful and accessible modern language for advanced biomedical concept representation and manipulation. The text also includes humor, history, and anecdotal material to balance the mathematically and computationally intensive development in many of the topic areas. The emphasis, as in the first edition, is on ideas and methods that are likely to be of lasting value, not just the popular topics of the day. Ira Kalet is Professor Emeritus of Radiation Oncology, and of Biomedical Informatics and Medical Education, at the University of Washington. Until retiring in 2011 he was also an Adjunct Professor in Computer Science and Engineering, and Biological Structure. From 2005 to 2010 he served as IT Security Director for the University of Washington School of Medicine and its major teaching hospitals. He has been a member of the American Medical Informatics Association since 1990, and an elected Fellow of the American College of Medical Informatics since 2011. His research interests include simulation systems for design of radiation treatment for cancer, software development methodology, and artificial intelligence applications to medicine, particularly expert systems, ontologies and modeling. Develops principles and methods for representing biomedical data, using information in context and in decision making, and accessing information to assist the medical community in using data to its full potential Provides a series of principles for expressing biomedical data and ideas in a computable form to integrate biological, clinical, and public health applications Includes a discussion of user interfaces, interactive graphics, and knowledge resources and reference material on programming languages to provide medical informatics programmers with the technical tools to develop systems

Health Informatics Data Analysis

Health Informatics Data Analysis
Author: Dong Xu,May D. Wang,Fengfeng Zhou,Yunpeng Cai
Publsiher: Springer
Total Pages: 210
Release: 2017-09-08
Genre: Medical
ISBN: 9783319449814

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This book provides a comprehensive overview of different biomedical data types, including both clinical and genomic data. Thorough explanations enable readers to explore key topics ranging from electrocardiograms to Big Data health mining and EEG analysis techniques. Each chapter offers a summary of the field and a sample analysis. Also covered are telehealth infrastructure, healthcare information association rules, methods for mass spectrometry imaging, environmental biodiversity, and the global nonlinear fitness function for protein structures. Diseases are addressed in chapters on functional annotation of lncRNAs in human disease, metabolomics characterization of human diseases, disease risk factors using SNP data and Bayesian methods, and imaging informatics for diagnostic imaging marker selection. With the exploding accumulation of Electronic Health Records (EHRs), there is an urgent need for computer-aided analysis of heterogeneous biomedical datasets. Biomedical data is notorious for its diversified scales, dimensions, and volumes, and requires interdisciplinary technologies for visual illustration and digital characterization. Various computer programs and servers have been developed for these purposes by both theoreticians and engineers. This book is an essential reference for investigating the tools available for analyzing heterogeneous biomedical data. It is designed for professionals, researchers, and practitioners in biomedical engineering, diagnostics, medical electronics, and related industries.