Micro and Nanotechnology in Vaccine Development

Micro  and Nanotechnology in Vaccine Development
Author: Mariusz Skwarczynski,Istvan Toth
Publsiher: William Andrew
Total Pages: 460
Release: 2016-09-20
Genre: Medical
ISBN: 9780323400299

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This book provides a comprehensive overview of how use of micro- and nanotechnology (MNT) has allowed major new advance in vaccine development research, and the challenges that immunologists face in making further progress. MNT allows the creation of particles that exploit the inherent ability of the human immune system to recognize small particles such as viruses and toxins. In combination with minimal protective epitope design, this permits the creation of immunogenic particles that stimulate a response against the targeted pathogen. The finely tuned response of the human immune system to small particles makes it unsurprising that many of the lead adjuvants and vaccine delivery systems currently under investigation are based on nanoparticles. Provides a comprehensive and unparalleled overview of the role of micro- and nanotechnology in vaccine development Allows researchers to quickly familiarize themselves with the broad spectrum of vaccines and how micro- and nanotechnologies are applied to their development Includes a combination of overview chapters setting out general principles, and focused content dealing with specific vaccines, making it useful to readers from a variety of disciplines

Nanotechnologies in Preventive and Regenerative Medicine

Nanotechnologies in Preventive and Regenerative Medicine
Author: Vuk Uskokovic
Publsiher: Elsevier
Total Pages: 616
Release: 2017-11-22
Genre: Medical
ISBN: 9780323480642

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Nanotechnologies in Preventative and Regenerative Medicine demonstrates how control at the nanoscale can help achieve earlier diagnoses and create more effective treatments. Chapters take a logical approach, arranging materials by their area of application. Biomaterials are, by convention, divided according to the area of their application, with each chapter outlining current challenges before discussing how nanotechnology and nanomaterials can help solve these challenges This applications-orientated book is a valuable resource for researchers in biomedical science who want to gain a greater understanding on how nanotechnology can help create more effective vaccines and treatments, and to nanomaterials researchers seeking to gain a greater understanding of how these materials are applied in medicine. Demonstrates how nanotechnology can help achieve more successful diagnoses at an earlier stage Explains how nanomaterials can be manipulated to create more effective drug treatments Offers suggestions on how the use of nanotechnology might have future applications to create even more effective treatments

Nanotherapeutics in Cancer Vaccination and Challenges

Nanotherapeutics in Cancer Vaccination and Challenges
Author: Mahfoozur Rahman,Sarwar Beg,Waleed H. Almalki,Nabil A. Alhakamy,Hani Choudhry
Publsiher: Academic Press
Total Pages: 494
Release: 2022-03-03
Genre: Business & Economics
ISBN: 9780128236871

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Nanotherapeutics in Cancer Vaccination and Challenges consolidates the current research on cancer nanomedicine and therapeutic cancer vaccination to explore the most effective and promising avenues. The book covers cancer vaccines before exploring nanotherapeutics, DNA and mRNA vaccines in cancer treatment. Finally, it considers regulatory and industrial perspectives on cancer vaccination and nanotherapeutics. This resource will be useful for pharmaceutical scientists and researchers focused on biomedical engineering, chemical engineering, vaccine development, and cancer immunotherapy, along with advanced students in these subjects. Cancer is arguably the most complex and challenging disease known to mankind. Over the last two-decades, significant advancements have been made in new and novel concepts of cancer nanomedicines. Therapeutic cancer vaccines may be utilized to inhibit further growth of advanced cancers and/or relapsed tumors that are refractory to conventional therapies, such as surgery, radiation therapy and chemotherapy. Presents the progress made in cancer medicines from conventional to targeted therapy Covers the present state-of-the-art of cancer nanomedicines and upcoming therapeutic cancer vaccination Contains a focus on advanced nanomaterials that are utilized for encapsulation of nucleic acid, mRNA, DNA, siRNA

Micro and Nanotechnologies for Biotechnology

Micro and Nanotechnologies for Biotechnology
Author: Stefan G. Stanciu
Publsiher: BoD – Books on Demand
Total Pages: 154
Release: 2016-08-24
Genre: Science
ISBN: 9789535125303

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Countless healthcare and biomedical solutions with high impact in terms of timely diagnostics, therapeutic success, patient comfort or financial sustainability of healthcare systems rely on micro- and nanotechnologies. Thus, it is not at all exaggerate to claim that such technologies play in current days a tremendous role with respect to improving the quality of our life, health and well-being, which are the main priorities of modern science. This volume illustrates these statements, addressing highly significant scientific subjects from diverse areas of micro- and nanotechnologies for biotechnology. Authoritative voices in their fields present in this volume their work, or review recent trends, concepts and applications, in a manner that is accessible to a broad readership audience from both within and outside their specialist area.

Emerging Nanomaterials and Nano based Drug Delivery Approaches to Combat Antimicrobial Resistance

Emerging Nanomaterials and Nano based Drug Delivery Approaches to Combat Antimicrobial Resistance
Author: Muthupandian Saravanan,Hamed Barabadi,Ebrahim Mostafavi,Thomas J. Webster
Publsiher: Elsevier
Total Pages: 788
Release: 2022-06-24
Genre: Technology & Engineering
ISBN: 9780323998109

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Emerging Nanomaterials and Nano-based Drug Delivery Approaches to Combat Antimicrobial Resistance focuses on recent and emerging trends surrounding nanomaterials and nano-drug delivery approaches to combat antimicrobial resistance. The relationship between nanomaterials and antimicrobial activity needs to be deeply explored to meet the challenges of combating antimicrobial resistance. The content of this book is divided into three main topic areas, including (i) how to overcome the existing traditional approaches to combat antimicrobial resistance, (ii) applying multiple drug delivery mechanisms to target multi-drug resistant microbes, and (iii) how nanomaterials can be used as drug carriers. This is an important reference source for those looking to understand how nanotechnology plays an important role in combatting disease and infection. As antimicrobial resistance threatens the effective prevention and treatment of an ever-increasing range of infections caused by bacteria, parasites, viruses, and fungi, this is a timely resource. Outlines how to overcome existing traditional approaches to combatting antimicrobial resistance Explains how to apply multiple drug delivery mechanisms (MDR) to the target area in order to better combat antimicrobial resistance Shows how nanomaterials are used as drug carriers in this context

Drug Delivery Technology Development in Canada

Drug Delivery Technology Development in Canada
Author: Kishor M.Wasan,Ildiko Badea
Publsiher: MDPI
Total Pages: 352
Release: 2019-12-19
Genre: Science
ISBN: 9783039280049

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Canada continues to have a rich history of ground-breaking research in drug delivery within academic institutions, pharmaceutical industry and the biotechnology community. Over the past 30 years, numerous Canadian-based biotechnology companies have been formed from the inventions conceived and developed within academic institutions that have led to the development of important drug delivery products that have enhanced the landscape of drug therapy in the treatment of cancer to infectious diseases. This Special Issue serves to highlight and capture the contemporary progress of drug delivery within the prevailing Canadian context. We invite articles on all aspects of drug delivery sciences from pre-clinical formulation development to human clinical trials that bring to light the world-class research currently undertaken in Canada for this Special Issue.

Synthetic Peptide Vaccine Models

Synthetic Peptide Vaccine Models
Author: Mesut Karahan
Publsiher: CRC Press
Total Pages: 292
Release: 2021-03-01
Genre: Science
ISBN: 9781000342772

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A new generation of technological vaccines protect against many infectious diseases. This book describes synthetic peptide-based vaccine prototypes – the future of vaccination. Production of peptides becomes simple using automatic synthesizers. Peptides are weak immunogen and need adjuvants to provide an effective autoimmune response, which is why peptide antigens are conjugated with biopolymers and loaded with nanoparticles. The book illustrates the use of peptides vaccine systems and makes predictions of future development not only for infectious diseases, but also for cancers and brain diseases such as Alzheimer, Parkinson and psychiatric diseases. Key Features Summarizes current studies on technological vaccines Describes the uses of vaccines for the prevention of brain diseases Reviews the ways different polymers are used to enhance vaccine efficacy

Nanomaterials for Clinical Applications

Nanomaterials for Clinical Applications
Author: Costas Demetzos,Natassa Pippa
Publsiher: Elsevier
Total Pages: 322
Release: 2020-02-14
Genre: Technology & Engineering
ISBN: 9780128168769

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Nanomaterials in Clinical Medicine: Case Studies in Nanomedicines focuses on the nanomaterials that can be formulated as drug delivery vehicles, such as liposomes, micelles, nanoemulsions and nanogels. Their physicochemical, morphological, thermo-dynamical and nanotoxicological properties are analyzed with respect to the design and development of drug delivery nanosystems for the encapsulation of an active pharmaceutical ingredient and its controlled release. Each chapter covers basic properties, the nanosystem (e.g., liposomes), the added value in drug delivery and targeting, and future perspectives. Case studies and examples of how nanomaterials are being used in clinical medicine, including marketed liposomal medicines and medical utility and regimens are also included. Particular attention is given to new nanocarriers, such as elastic liposomes, lipid polymeric hybrid nanoparticles, organogel, nanofibers carbon nanomaterials, quantum dots and inorganic nanoparticles. This book is an important information source for those wanting to increase their understanding of what major nanomaterials are being used to create more effective drug delivery systems. Summarizes the major nanomaterials used in clinical medicine, explaining how their properties make them suitable for this purpose Explains how nanomaterials are used to create increasingly efficient drug delivery vehicles Includes real-life examples, demonstrating how nanomaterials are being used in medical practice

Nanoparticles for Rational Vaccine Design

Nanoparticles for Rational Vaccine Design
Author: Harvinder Singh Gill,Richard W. Compans
Publsiher: Springer Nature
Total Pages: 130
Release: 2021-08-30
Genre: Medical
ISBN: 9783030850678

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This book introduces nanoparticles as a powerful platform for vaccine design. Current challenges in vaccine development are discussed and the unique advantages nanoparticles provide in overcoming these challenges are explored. The authors offer fascinating insights into the immunological assets of using nanoparticles as delivery vehicles or adjuvants and present different materials that are being used in nanoparticle-based vaccine development, covering peptides, proteins, polymers, virus-like particles, and liposomes. Its contemporary research insights and practical examples for applications make this volume an inspiring read for researchers and clinicians in vaccinology and immunology. Chapter "Liposome Formulations as Adjuvants for Vaccines" is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Industrial Applications of Nanomaterials

Industrial Applications of Nanomaterials
Author: Sabu Thomas,Yves Grohens,Yasir Beeran Pottathara
Publsiher: Elsevier
Total Pages: 534
Release: 2019-08-12
Genre: Technology & Engineering
ISBN: 9780128157503

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Industrial Applications of Nanomaterials explains the industry based applications of nanomaterials, along with their environmental impacts, lifecycle analysis, safety and sustainability. This book brings together the industrial applications of nanomaterials with the incorporation of various technologies and areas, covering new trends and challenges. Significant properties, safety and sustainability and environmental impacts of synthesis routes are also explored, as are major industrial applications, including agriculture, medicine, communication, construction, energy, and in the military. This book is an important information source for those in research and development who want to gain a greater understanding of how nanotechnology is being used to create cheaper, more efficient products. Explains how different classes of nanomaterials are being used to create cheaper, more efficient products Explores the environmental impacts of using a variety of nanomaterials Discusses the challenges faced by engineers looking to integrate nanotechnology in new product development

Surfactants and Detergents

Surfactants and Detergents
Author: Ashim Dutta
Publsiher: BoD – Books on Demand
Total Pages: 102
Release: 2019-11-20
Genre: Science
ISBN: 9781789846607

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Surfactants by virtue of their structure form self-assembled organized structures that exhibit fascinating properties useful for a wide range of applications. This book is a compilation of chapters from leading experts highlighting the use of specific surfactants and their functional properties in new and emerging areas of science and technology. The first two chapters of this book discuss the various applications of surfactants, including their use in cosmetics, oil recovery from rocks and mineral processing. Subsequent chapters cover advanced topics like new-generation polymer-based nanoparticles with microbial activity and complex phase systems formed as a result of charge-induced interactions between surfactants, polymers and proteins with potential applications in medical devices. In addition, this book reports for the first time on bio-surfactants extracted from micro-organisms present in the clouds. This report is not the only one of its kind, but it opens up a totally new area of research in terms of an unexplored source of bio-surfactants. It also paves the way for understanding their role in controlling our atmosphere and climate.

Engineering Drug Delivery Systems

Engineering Drug Delivery Systems
Author: Ali Seyfoddin,Seyedehsara Masoomi Dezfooli,Carol Ann Greene
Publsiher: Woodhead Publishing
Total Pages: 250
Release: 2019-11-15
Genre: Medical
ISBN: 9780081025499

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Engineering Drug Delivery Systems is an essential resource on a variety of biomaterials engineering approaches for creating drug delivery systems that have market and therapeutic potential. The book comprehensively discusses recent advances in the fields of biomaterials and biomedical sciences in relation to drug delivery. Chapters provide a detailed introduction to various engineering approaches in designing drug delivery systems, delve into the engineering of body functions, cover the selection, design and evaluation of biomaterials, and discuss the engineering of colloids as drug carriers. The book's final chapters address the engineering of implantable drug delivery systems and advances in drug delivery technology. This book is an invaluable resource for drug delivery, materials scientists and bioengineers within the pharmaceutical industry. Examines the properties and synthesis of biomaterials for successful drug delivery Discusses the important connection between drug delivery and tissue engineering Includes techniques and approaches applicable to a wide range of users Reviews innovative technologies in drug delivery systems such as 3-D printed devices for drug delivery

Nanotechnology Applications in Environmental Engineering

Nanotechnology Applications in Environmental Engineering
Author: Nazir, Rabia
Publsiher: IGI Global
Total Pages: 469
Release: 2018-08-03
Genre: Technology & Engineering
ISBN: 9781522557463

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Nanotechnology is the twenty-first century revolution that has impacted each and every aspect of life despite its small size. As nanoscale research continues to advance, scientists and engineers are developing new applications for many different disciplines, including environmental applications. Nanotechnology Applications in Environmental Engineering contains innovative research on nanomaterials and their impact on the environment. It also explores the current and potential future applications of nanodevices in environmental science and engineering, showcasing how nanomaterials can be tailored to address some of the environmental remediation and sensing/detection problems faced today. While highlighting topics such as environmental science, nanomaterials, and membrane technology, this book is ideally designed for environmental scientists, nanotechnologists, chemists, engineers, and individuals seeking current research on nanotechnology and its applications in environmental engineering.

Transmucosal Absorption Enhancers in the Drug Delivery Field

Transmucosal Absorption Enhancers in the Drug Delivery Field
Author: Luca Casettari,Sam Maher,Lisbeth Illum
Publsiher: MDPI
Total Pages: 406
Release: 2020-01-07
Genre: Medical
ISBN: 9783039218486

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Development of strategies to assist the movement of poorly permeable molecules across biological barriers has long been the goal of drug delivery science. In the last three decades, there has been an exponential increase in advanced drug delivery systems that aim to address this issue. However, most proprietary delivery technologies that have progressed to clinical development are based on permeation enhancers (PEs) that have a history of safe use in man. This Special Issue entitled “Transmucosal Absorption Enhancers in the Drug Delivery Field” aims to present the current state-of-the-art in the application of PEs to improve drug absorption. Emphasis is placed on identification of novel permeation enhancers, mechanisms of barrier alteration, physicochemical properties of PEs that contribute to optimal enhancement action, new delivery models to assess PEs, studies assessing safety of PEs, approaches to assist translation of PEs into effective oral, nasal, ocular and vaginal dosage forms and combining PEs with other delivery strategies.

Introduction to Molecular Vaccinology

Introduction to Molecular Vaccinology
Author: Matthias Giese
Publsiher: Springer
Total Pages: 373
Release: 2016-03-11
Genre: Medical
ISBN: 9783319258324

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This textbook provides an easy-to-understand introduction to the complex topic of vaccine research and development. It gives a comprehensive though clearly arranged insight to the most important aspects of molecular vaccinology, leading from the basics in immunology, to design of vaccines and mode of action of vaccines to the actual formulation, manufacturing and registration of vaccines. The volume is therefore a valuable text about modern vaccinology for graduate students and a basic introduction for newcomers in vaccine design and development.