Nanobiomaterials in Antimicrobial Therapy

Nanobiomaterials in Antimicrobial Therapy
Author: Alexandru Grumezescu
Publsiher: William Andrew
Total Pages: 576
Release: 2016-03-08
Genre: Science
ISBN: 9780323428873

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Nanobiomaterials in Antimicrobial Therapy presents novel antimicrobial approaches that enable nanotechnology to be used effectively in the treatment of infections. This field has gained a large amount of interest over the last decade, in response to the high resistance of pathogens to antibiotics. Leading researchers from around the world discuss the synthesis routes of nanobiomaterials, characterization, and their applications as antimicrobial agents. The books covers various aspects: mechanisms of toxicity for inorganic nanoparticles against bacteria; the development of excellent carriers for the transport of a high variety of antimicrobials; the use of nanomaterials to facilitate both diagnosis and therapeutic approaches against infectious agents; strategies to control biofilms based on enzymes, biosurfactants, or magnetotactic bacteria; bacterial adhesion onto polymeric surfaces and novel materials; and antimicrobial photodynamic inactivation. This book will be of interest to postdoctoral researchers, professors and students engaged in the fields of materials science, biotechnology and applied chemistry. It will also be highly valuable to those working in industry, including pharmaceutics and biotechnology companies, medical researchers, biomedical engineers and advanced clinicians. A methodical approach to this highly relevant subject for researchers, practitioners and students working in biomedical, biotechnological and engineering fields A valuable guide to recent scientific progress and the latest application methods Proposes novel opportunities and ideas for developing or improving technologies in nanomedicine and nanobiology

Nanostructures for Antimicrobial Therapy

Nanostructures for Antimicrobial Therapy
Author: Anton Ficai,Alexandru Mihai Grumezescu
Publsiher: Elsevier
Total Pages: 722
Release: 2017-05-29
Genre: Medical
ISBN: 9780323461511

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Nanostructures for Antimicrobial Therapy discusses the pros and cons of the use of nanostructured materials in the prevention and eradication of infections, highlighting the efficient microbicidal effect of nanoparticles against antibiotic-resistant pathogens and biofilms. Conventional antibiotics are becoming ineffective towards microorganisms due to their widespread and often inappropriate use. As a result, the development of antibiotic resistance in microorganisms is increasingly being reported. New approaches are needed to confront the rising issues related to infectious diseases. The merging of biomaterials, such as chitosan, carrageenan, gelatin, poly (lactic-co-glycolic acid) with nanotechnology provides a promising platform for antimicrobial therapy as it provides a controlled way to target cells and induce the desired response without the adverse effects common to many traditional treatments. Nanoparticles represent one of the most promising therapeutic treatments to the problem caused by infectious micro-organisms resistant to traditional therapies. This volume discusses this promise in detail, and also discusses what challenges the greater use of nanoparticles might pose to medical professionals. The unique physiochemical properties of nanoparticles, combined with their growth inhibitory capacity against microbes has led to the upsurge in the research on nanoparticles as antimicrobials. The importance of bactericidal nanobiomaterials study will likely increase as development of resistant strains of bacteria against most potent antibiotics continues. Shows how nanoantibiotics can be used to more effectively treat disease Discusses the advantages and issues of a variety of different nanoantibiotics, enabling medics to select which best meets their needs Provides a cogent summary of recent developments in this field, allowing readers to quickly familiarize themselves with this topic area

Handbook of Research on Nano Strategies for Combatting Antimicrobial Resistance and Cancer

Handbook of Research on Nano Strategies for Combatting Antimicrobial Resistance and Cancer
Author: Saravanan, Muthupandian,Gopinath, Venkatraman,Deekonda, Karthik
Publsiher: IGI Global
Total Pages: 559
Release: 2021-02-12
Genre: Medical
ISBN: 9781799850502

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Multidrug-resistant bacteria play a significant role in public health by destroying the potency of existing antibiotics. Meanwhile, cancer remains one of the most common health problems that impact society, resulting in many deaths worldwide. Novel strategies are required to combat antimicrobial resistance and create efficient anticancer drugs that could revolutionize treatment. Nanomedicine is one such innovation that plays a significant role in developing alternative and more effective treatment strategies for antimicrobial resistance and cancer theranostics. The Handbook of Research on Nano-Strategies for Combatting Antimicrobial Resistance and Cancer is an essential scholarly resource that examines (1) how to overcome the existing, traditional approaches to combat antimicrobial resistance and cancer; (2) how to apply multiple mechanisms to target the cancer cells and microbes; and (3) how the nanomaterials can be used as carriers. Featuring a range of topics such as bacteriophage, nanomedicine, and oncology, this book is ideal for molecular biologists, microbiologists, nanotechnologists, academicians, chemists, pharmacists, oncologists, researchers, healthcare professionals, and students.

Antimicrobial Nanoarchitectonics

Antimicrobial Nanoarchitectonics
Author: Alexandru Mihai Grumezescu
Publsiher: William Andrew
Total Pages: 574
Release: 2017-06-22
Genre: Technology & Engineering
ISBN: 9780323527347

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Antimicrobial Nanoarchitectonics: From Synthesis to Applications brings together recent research in antimicrobial nanoparticles, specifically in the sustained and controlled delivery of antimicrobials. Particular attention is given to i) reducing the side effects of antibiotics, ii) increasing the pharmacological effect, and iii) improving aqueous solubility and chemical stability of different antimicrobials. In addition, antimicrobial nanoparticles in drug delivery are discussed extensively. The book also evaluates the pros and cons of using nanostructured biomaterials in the prevention and eradication of infections. It is an important reference resource for materials scientists and bioengineers who want to learn how nanomaterials are used in antimicrobial therapy. Provides readers with the information necessary to select the appropriate bionanomaterial to solve particular infection problems Includes case studies, showing how particular bionanomaterials have been used to cure infections Explains the central role that nanotechnology plays in modern antimicrobial therapy Evaluates the pros and cons of using nanostructured biomaterials in the prevention and eradication of infections

Nanotechnology in Diagnosis Treatment and Prophylaxis of Infectious Diseases

Nanotechnology in Diagnosis  Treatment and Prophylaxis of Infectious Diseases
Author: Mahendra Rai,Kateryna Kon
Publsiher: Academic Press
Total Pages: 344
Release: 2015-05-23
Genre: Medical
ISBN: 9780128014714

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Nanotechnology in Diagnosis, Treatment and Prophylaxis of Infectious Diseases delivers comprehensive coverage of the application of nanotechnology to pressing problems in infectious disease. This text equips readers with cutting-edge knowledge of promising developments and future prospects in nanotechnology, paying special attention to microbes that are now resistant to conventional antibiotics, a concerning problem in modern medicine. Readers will find a thorough discussion of this new approach to infectious disease treatment, including the reasons nanotechnology presents a promising avenue for the diagnosis, treatment, and prophylaxis of infectious diseases. Provides a comprehensive overview of the use of nanotechnology in the treatment and diagnosis of infectious diseases Covers all common types of infective agents, including bacteria, viruses, fungi, and protozoa, along with their vectors, ticks, mosquitoes, flies, etc. Delivers commentary from an international researcher base, providing insights across differing economic statuses Includes a foundation of basic nanotechnological concepts to aid in designing new strategies to combat several pathogenic diseases and cancer Illustrates the high antimicrobial potential of nanoparticles, ultimately demonstrating how they are a promising alternative class that can be successfully used in fighting a myriad of infections

Antibiotic Materials in Healthcare

Antibiotic Materials in Healthcare
Author: Kokkarachedu Varaprasad,Vimala Kanikireddy,Rotimi Sadiku
Publsiher: Academic Press
Total Pages: 346
Release: 2020-05-22
Genre: Science
ISBN: 9780128225363

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Antibiotic Materials in Healthcare provides significant information on antibiotic related issues, accurate solutions, and recent investigative information for health-related applications. In addition, the book addresses the design and development of antibiotics with advanced (physical, chemical and biological) properties, an analysis of materials, in vivo and in vitro applications, and their biomedical applications for healthcare. Provides information on all aspects of antibiotic related issues Offers a balanced synthesis of basic and clinical science for each individual case, presenting clinical courses and detailed microbiological information for each infection Describes the prevalence and incidence of global issues and current therapeutic approaches

Antibacterial Agents

Antibacterial Agents
Author: Ranjith Kumavath
Publsiher: BoD – Books on Demand
Total Pages: 138
Release: 2017-05-31
Genre: Science
ISBN: 9789535131991

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New drugs are frequently entering into the market along with the existing drugs. The antibacterial agents can be discussed in five major classes, i.e. classification based on the type of action, source, spectrum of activity, chemical structure and function. Resistance of bacteria to antibiotics is an urgent problem of the humanity, which leads us to the lack of therapy for serious bacterial infections. Development of new antibiotics has almost ceased in the last decades - even when a new antibiotic is launched, very soon the resistance of bacteria appears. Industrial textiles exposed as awnings, screens, tents; upholstery used in large public areas such as hospitals, hotels and stations; fabrics for transports; protective clothing and personal protective equipment; bed sheets and blankets; textiles left wet between processing steps; intimate apparel, underwear, socks and sportswear, disinfection of air and water for white rooms, hospitals and operating theatres, food and pharma industries, water depuration, drinkable water supplying and air conditioning systems. Many clinicians recommend alternative approaches to using antimicrobial substances. Moreover, the majority of bioagents demonstrate on antibiotics for treatment of a wide range of diseases in human sectors. However, the misuse and mishandling of drugs lead to microbial, particularly bacterial, resistance as well as result in the difficulty of treating microbial diseases. Hence, the proposed book will give more precise information on novel antibacterial compound(s).

Nano biomaterials in Antimicrobial Therapy

Nano biomaterials in Antimicrobial Therapy
Author: Pratima Parashar Pandey
Publsiher: Unknown
Total Pages: 135
Release: 2016
Genre: Science
ISBN: OCLC:1154162130

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Silver nanoparticles (AgNps) have attracted much interest in biomedical engineering, since they have excellent antimicrobial properties. Silver nanopolymer composites have applications in biochemical sensors, antimicrobial activity and drug delivery system. Silver nanoparticles are more effective than ionic homologues (Ag+) for their antimicrobial activity. Antimicrobial properties of silver nanoparticles are used by their incorporation into medical devices, tissues and other health-related products for skin pathologies to reduce the risk of contamination and to promote higher preventive infection control. Novel hybrid material thin films based on various polymeric systems with embedded silver nanoparticles were synthesized using various methods. The electrical, optical and plasmonic responses of AgNps onto thin layers of polymer composites show encapsulation of nanoparticles. The antibacterial activity of AgNps/polymer composites against various common bacteria is discussed in this chapter. The antibacterial activity of the synthesized hybrid materials was tested against various bacteria, commonly found in hospital environment. Silver nanostructures have especially been of interest because of contrast agents for biomedical image. Shunts used for hydrocephalous silicon elastomer grafted with hydrogel, polyvinylpyrrolidone (PVP) soaked in various antibiotics proved to be active for longer time.