Pan genomics Applications Challenges and Future Prospects

Pan genomics  Applications  Challenges  and Future Prospects
Author: Debmalya Barh,Siomar C. Soares,Sandeep Tiwari,Vasco Azevedo
Publsiher: Academic Press
Total Pages: 474
Release: 2020-03-06
Genre: Medical
ISBN: 9780128170779

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Pan-genomics: Applications, Challenges, and Future Prospects covers current approaches, challenges and future prospects of pan-genomics. The book discusses bioinformatics tools and their applications and focuses on bacterial comparative genomics in order to leverage the development of precise drugs and treatments for specific organisms. The book is divided into three sections: the first, an "overview of pan-genomics and common approaches, brings the main concepts and current approaches on pan-genomics research; the second, “case studies in pan-genomics, thoroughly discusses twelve case, and the last, “current approaches and future prospects in pan-multiomics , encompasses the developments on omics studies to be applied on bacteria related studies. This book is a valuable source for bioinformaticians, genomics researchers and several members of biomedical field interested in understanding further bacterial organisms and their relationship to human health. Covers the entire spectrum of pangenomics, highlighting the use of specific approaches, case studies and future perspectives Discusses current bioinformatics tools and strategies for exploiting pangenomics data Presents twelve case studies with different organisms in order to provide the audience with real examples of pangenomics applicability

Introduction to Molecular Genomics

Introduction to Molecular Genomics
Author: Maryam Javed,Asif Nadeem, Faiz-ul Hassan
Publsiher: Bentham Science Publishers
Total Pages: 190
Release: 2021-11-02
Genre: Science
ISBN: 9781681089263

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Introduction to Molecular Genomics introduces the college student to the fundamental concepts of molecular biology and genomics. The text puts an emphasis on important topics in the subject that contribute to the learner’s understanding. These topics include molecular genomics, biodiversity and molecular phenomenon behind evolution of species, modern molecular methods for enhanced genomics research, DNA modifications at the molecular level for transgenic animal species, the role of cell environment on the gene expression, to name a few. The book has been designed to suit the requirements of educational courses in molecular biology, genomics and biochemistry. Key features - Covers basic concepts on key topics in molecular biology and genomics - Simple easy-to-read layout - Includes references for further reading - Includes a section on ethical aspects of scientific research Introduction to Molecular Genomics is a simple primer for students in applied or advanced life science courses at undergraduate levels

Lactic Acid Bacteria in Food Biotechnology

Lactic Acid Bacteria in Food Biotechnology
Author: Spiros Paramithiotis,Vasco Ariston De Carvalho4 Azevedo,Didier Montet
Publsiher: Elsevier
Total Pages: 382
Release: 2022-04-29
Genre: Science
ISBN: 9780323886338

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Lactic Acid Bacteria in Food Biotechnology: Innovations and Functional Aspects describes the latest advancements in LAB applications in the development of functional foods and fermented foods, biotechnological products using LAB, i.e., bio chemicals (organic acids, bacteriocins, etc.), bioactive and functional biomolecules, comparative genomics of probiotic LAB, and genetically modified LAB in food industry. Bridging the gap between LAB-mediated fermented foods and bioactive compounds, vis-a-vis molecular aspects, this book enables the transition from research to application. The book details applications of LAB in fermented/functional foods including cereals, vegetables, fish, meat cheese, other dairy products, and much more. Other sections cover their biochemistry and biotechnology aspects, bio preservation by bio molecules produced by LAB, bioactive metabolites and biosurfactants, including their value in health and wellness and exploring the genomics of LAB from food to health. Finally, the book addresses genetically modified lactic acid bacteria in food and beverages. Identifies biomolecules released by LAB into foods and their health benefits Describes natural biopreservation by LAB, mechanisms, food safety issues and disease prevention Includes LAB as probiotics, modulation of gut microbiota and health aspects Addresses potentially negative aspects of LAB in producing biogenic amines and health impacts Presents the pros and cons of genetically modified LAB in food industry

Frontiers in Molecular Pharming

Frontiers in Molecular Pharming
Author: Muhammad Sarwar Khan
Publsiher: Bentham Science Publishers
Total Pages: 415
Release: 2021-12-09
Genre: Science
ISBN: 9789815036671

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The advent of large-scale production and clinical trials of drugs developed through diverse production routes - involving viruses, microbes, plants, and animals - has increased the demand for an expanded capacity for pharmaceutical manufacturing. The production and purification of expressed proteins accounts for the bulk of the manufacturing costs for new therapeutics. Several pharmaceutical proteins have been synthesized by exploiting plant genetics allowing producers to override conventional approaches used to manufacture pharmaceuticals. The process of inserting a gene into a host organism for the purpose of harvesting a bioactive molecule for therapeutic use is known as molecular pharming. Frontiers in Molecular Pharming covers an array of topics relevant to understanding the structure, function, regulation, and mechanisms of action, biochemical significance, and usage of proteins and peptides as biomarkers, therapeutics, and vaccines for animals and humans. The contributions aim to highlight current progress in three areas, including system biology (in vivo characterization of proteins and peptides), molecular pharming for animals and molecular pharming for humans. The book gives special attention to computational biology tools, production platforms and fields (such as immunoinformatics) and applications of molecular pharming (such as veterinary therapeutics). A balance of theoretical concepts and practical applications is provided through 13 chapters. Frontiers in Molecular Pharming is an invaluable resource for students and researchers of biochemistry, molecular biology, and biotechnology. The book also serves as a springboard for understanding the process of how discoveries in protein and peptide research and its applications are coming to fruition.

Recent Advancement in Microbial Biotechnology

Recent Advancement in Microbial Biotechnology
Author: Surajit De Mandal,Ajit Kumar Passari
Publsiher: Elsevier
Total Pages: 478
Release: 2021-08-27
Genre: Science
ISBN: 9780128232613

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The rapid increase in microbial resources along with the development of biotechnological methods has revolutionized the field of microbial biotechnology. Genome characterization methods and metagenomic approaches further illustrate the role of microorganisms in various fields of research. Recent Advancement in Microbial Biotechnology: Agricultural and Industrial Approach provides an overview on the recent application of the microorganisms in agricultural and industrial improvements. The purpose of this book is to integrate all these diverse areas of research in a common platform. Recent advancement in Microbial Biotechnology targets researchers from both academia and industry, professors and graduate students working in molecular biology, microbiology and biotechnology. Gives insight in the exploration of microbial functional diversity in different systems Highlights important microbes and their role in enhancing agricultural productivity Provides understanding to the basics with advance information of microbial biotechnology Explores the importance of microbial genomes studies in agricultural and industrial applications

Streptococcus spp and Corynebacterium spp Clinical and Zoonotic Epidemiology Virulence Potential Antimicrobial Resistance and Genomic Trends and Approaches

Streptococcus spp  and Corynebacterium spp   Clinical and Zoonotic Epidemiology  Virulence Potential  Antimicrobial Resistance and Genomic Trends and Approaches
Author: Prescilla Emy Nagao,Andreas Burkovski,Ana Luíza Mattos Guaraldi
Publsiher: Frontiers Media SA
Total Pages: 135
Release: 2022-03-17
Genre: Science
ISBN: 9782889747245

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Bioinformatics in Agriculture

Bioinformatics in Agriculture
Author: Pradeep Sharma,Dinesh Yadav,R.K. Gaur
Publsiher: Academic Press
Total Pages: 706
Release: 2022-04-26
Genre: Technology & Engineering
ISBN: 9780323885997

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Bioinformatics in Agriculture: Next Generation Sequencing Era is a comprehensive volume presenting an integrated research and development approach to the practical application of genomics to improve agricultural crops. Exploring both the theoretical and applied aspects of computational biology, and focusing on the innovation processes, the book highlights the increased productivity of a translational approach. Presented in four sections and including insights from experts from around the world, the book includes: Section I: Bioinformatics and Next Generation Sequencing Technologies; Section II: Omics Application; Section III: Data mining and Markers Discovery; Section IV: Artificial Intelligence and Agribots. Bioinformatics in Agriculture: Next Generation Sequencing Era explores deep sequencing, NGS, genomic, transcriptome analysis and multiplexing, highlighting practices forreducing time, cost, and effort for the analysis of gene as they are pooled, and sequenced. Readers will gain real-world information on computational biology, genomics, applied data mining, machine learning, and artificial intelligence. This book serves as a complete package for advanced undergraduate students, researchers, and scientists with an interest in bioinformatics. Discusses integral aspects of molecular biology and pivotal tool sfor molecular breeding Enables breeders to design cost-effective and efficient breeding strategies Provides examples ofinnovative genome-wide marker (SSR, SNP) discovery Explores both the theoretical and practical aspects of computational biology with focus on innovation processes Covers recent trends of bioinformatics and different tools and techniques

Plant Virus Host Interaction

Plant Virus Host Interaction
Author: R.K. Gaur,S.M. Paul Khurana,Pradeep Sharma,Thomas Hohn
Publsiher: Academic Press
Total Pages: 582
Release: 2021-01-12
Genre: Science
ISBN: 9780128244838

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Plant Virus-Host Interaction: Molecular Approaches and Viral Evolution, Second Edition, provides comprehensive coverage of molecular approaches for virus-host interaction. The book contains cutting-edge research in plant molecular virology, including pathogenic viroids and transport by insect vectors, interference with transmission to control viruses, synergism with pivotal coverage of RNA silencing, and the counter-defensive strategies used by viruses to overcome the silencing response in plants. This new edition introduces new, emerging proteins involved in host-virus interactions and provides in-depth coverage of plant virus genes’ interactions with host, localization and expression. With contributions from leading experts, this is a comprehensive reference for plant virologists, molecular biologists and others interested in characterization of plant viruses and disease management. Introduces new, emerging proteins involved during the host-virus interaction and new virus strains that invade new crops through recombination, resorting and mutation Provides molecular approaches for virus-host interaction Highlights RNA silencing and counter-defensive strategies for disease management Discusses the socioeconomic implications of viral spread and mitigation techniques

Nanobiotechnology

Nanobiotechnology
Author: Sougata Ghosh,Thomas J. Webster
Publsiher: Elsevier
Total Pages: 360
Release: 2021-05-20
Genre: Technology & Engineering
ISBN: 9780128231159

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Nanobiotechnology: Microbes and Plant Assisted Synthesis of Nanoparticles, Mechanisms and Applications covers in detail the green synthesis of nanostructures of tailor-made size, shape and physico-chemical and opto-electronic properties. The rationale behind the selection of bacteria, cyanobacteria, algae, fungi, virus and medicinal plants for the synthesis of biologically active exotic nanoparticles for biomedical applications is also part of this book. It also explores metal recovery, bioconversion, detoxification and removal of heavy metals using nanobiotechnology and discusses the potential of nanobiotechnology to address environmental pollution and toxicity. The book further covers the economic and commercial aspects of such green nanobiotechnology initiatives, its current status in intellectual property rights like patents filed so far globally, technology transfers, and market potential. This information enables one to decipher the scope of biogenic nanoparticles and its prospects. Provides an overview on the general and applied aspects on nanotechnology. Gives the scope of exploring bacteria, fungi, algae, virus and medicinal plants for the synthesis of exotic nanoparticles. Furnishes a comprehensive report on the underlying molecular mechanisms behind the biosynthesis of nanoparticles. Outlines sustainable alternative strategies of bioremediation of heavy metals, metal recovery, detoxification and bioconversion using nanobiotechnology. Explores the promises of patenting, technology transfer and commercialization potential of biogenic nanoparticles.

Microbes in Land Use Change Management

Microbes in Land Use Change Management
Author: Jay Shankar Singh,Shashank Tiwari,Chhatarpal Singh,Anil Kumar Singh
Publsiher: Elsevier
Total Pages: 598
Release: 2021-08-20
Genre: Science
ISBN: 9780323858946

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Microbes in Land Use Change Management details the various roles of microbial resources in management of land uses and how the microbes can be used for the source of income due to their cultivation for the purpose of biomass and bioenergy production. Using various techniques, the disturbed and marginal lands may also be restored eco-friendly in present era to fulfil the feeding needs of mankind around the globe. Microbes in Land Use Change Management provides standard and up to date information towards the land use change management using various microbial technologies to enhance the productivity of agriculture. Needless to say that Microbes in Land Use Change Management also considers the areas including generation of alternative energy sources, restoration of degraded and marginal lands, mitigation of global warming gases and next generation -omics technique etc. Land use change affects environment conditions and soil microbial community. Microbial population and its species diversity have influence in maintaining ecosystem balance. The study of changes of microbial population provides an idea about the variation occurring in a specific area and possibilities of restoration. Meant for a multidisciplinary audience Microbes in Land Use Change Management shows the need of next-generation omics technologies to explore microbial diversity. Describes the role of microbes in generation of alternative source of energy Gives recent information related to various microbial technology and their diversified applications Provides thorough insight in the problems related to landscape dynamics, restoration of soil, reclamation of lands mitigation of global warming gases etc. eco-friendly way using versatility of microbes Includes microbial tools and technology in reclamation of degraded, disturbed and marginal lands, mitigation of global warming gases

Microbial Biotechnology

Microbial Biotechnology
Author: Yuan Kun Lee
Publsiher: World Scientific Publishing Company
Total Pages: 896
Release: 2013-01-30
Genre: Science
ISBN: 9789814513098

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The rapidly expanding molecular biological techniques and approaches have significant impact on microbial biotechnology, hence the need for the addition of four new chapters in the third edition of this textbook — “Chapter 3: Application of ‘Omics’ Technologies in Microbial Fermentation”, “Chapter 5: Microbial Genome Mining for Identifying Antimicrobial Targets”, “Chapter 21: Bacterial Biofilm: Molecular Characterization and Impacts on Water Management” and “Chapter 23: Microbial Biomining”. “Chapter 15: Transgenic Plants” has been completely revised while most of the other chapters have been thoroughly updated in this new edition. There already exist a number of excellent general textbooks on microbiology and biotechnology that deal with the basic principles of microbial biotechnology. To complement them, this book focuses on the various applications of microbial-biotechnological principles. A teaching-based format is adopted, whereby working problems, as well as answers to frequently asked questions, supplement the main text. The book also includes real life examples of how the application of microbial-biotechnological principles has achieved breakthroughs in both research and industrial production. Although written for polytechnic students and undergraduates, the book contains sufficient information to be used as a reference for postgraduate students and lecturers. It may also serve as a resource book for corporate planners, managers and applied research personnel.

Intelligence Based Medicine

Intelligence Based Medicine
Author: Anthony C. Chang
Publsiher: Academic Press
Total Pages: 534
Release: 2020-06-27
Genre: Medical
ISBN: 9780128233382

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Intelligence-Based Medicine: Data Science, Artificial Intelligence, and Human Cognition in Clinical Medicine and Healthcare provides a multidisciplinary and comprehensive survey of artificial intelligence concepts and methodologies with real life applications in healthcare and medicine. Authored by a senior physician-data scientist, the book presents an intellectual and academic interface between the medical and the data science domains that is symmetric and balanced. The content consists of basic concepts of artificial intelligence and its real-life applications in a myriad of medical areas as well as medical and surgical subspecialties. It brings section summaries to emphasize key concepts delineated in each section; mini-topics authored by world-renowned experts in the respective key areas for their personal perspective; and a compendium of practical resources, such as glossary, references, best articles, and top companies. The goal of the book is to inspire clinicians to embrace the artificial intelligence methodologies as well as to educate data scientists about the medical ecosystem, in order to create a transformational paradigm for healthcare and medicine by using this emerging new technology. Covers a wide range of relevant topics from cloud computing, intelligent agents, to deep reinforcement learning and internet of everything Presents the concepts of artificial intelligence and its applications in an easy-to-understand format accessible to clinicians and data scientists Discusses how artificial intelligence can be utilized in a myriad of subspecialties and imagined of the future Delineates the necessary elements for successful implementation of artificial intelligence in medicine and healthcare

The Digital Agricultural Revolution

The Digital Agricultural Revolution
Author: Roheet Bhatnagar,Nitin Kumar Tripathi,Nitu Bhatnagar,Chandan Kumar Panda
Publsiher: John Wiley & Sons
Total Pages: 496
Release: 2022-05-17
Genre: Computers
ISBN: 9781119823445

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THE DIGITAL AGRICULTURAL REVOLUTION The book integrates computational intelligence, applied artificial intelligence, and modern agricultural practices and will appeal to scientists, agriculturists, and those in plant and crop science management. There is a need for synergy between the application of modern scientific innovation in the area of artificial intelligence and agriculture, considering the major challenges from climate change consequences viz. rising temperatures, erratic rainfall patterns, the emergence of new crop pests, drought, flood, etc. This volume reports on high-quality research (theory and practice including prototype & conceptualization of ideas, frameworks, real-world applications, policy, standards, psychological concerns, case studies, and critical surveys) on recent advances toward the realization of the digital agriculture revolution as a result of the convergence of different disruptive technologies. The book touches upon the following topics which have contributed to revolutionizing agricultural practices. Applications of Artificial Intelligence in Agriculture (AI models and architectures, system design, real-world applications of AI, machine learning and deep learning in the agriculture domain, integration & coordination of systems and issues & challenges). IoT and Big Data Analytics Applications in Agriculture (theory & architecture and the use of various types of sensors in optimizing agriculture resources and final product, benefits in real-time for crop acreage estimation, monitoring & control of agricultural produce). Robotics & Automation in Agriculture Systems (Automation challenges, need and recent developments and real case studies). Intelligent and Innovative Smart Agriculture Applications (use of hybrid intelligence in better crop health and management). Privacy, Security, and Trust in Digital Agriculture (government framework & policy papers). Open Problems, Challenges, and Future Trends. Audience Researchers in computer science, artificial intelligence, electronics engineering, agriculture automation, crop management, and science.

Genetically Engineered Crops

Genetically Engineered Crops
Author: National Academies of Sciences, Engineering, and Medicine,Division on Earth and Life Studies,Board on Agriculture and Natural Resources,Committee on Genetically Engineered Crops: Past Experience and Future Prospects
Publsiher: National Academies Press
Total Pages: 606
Release: 2017-01-28
Genre: Science
ISBN: 9780309437387

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Genetically engineered (GE) crops were first introduced commercially in the 1990s. After two decades of production, some groups and individuals remain critical of the technology based on their concerns about possible adverse effects on human health, the environment, and ethical considerations. At the same time, others are concerned that the technology is not reaching its potential to improve human health and the environment because of stringent regulations and reduced public funding to develop products offering more benefits to society. While the debate about these and other questions related to the genetic engineering techniques of the first 20 years goes on, emerging genetic-engineering technologies are adding new complexities to the conversation. Genetically Engineered Crops builds on previous related Academies reports published between 1987 and 2010 by undertaking a retrospective examination of the purported positive and adverse effects of GE crops and to anticipate what emerging genetic-engineering technologies hold for the future. This report indicates where there are uncertainties about the economic, agronomic, health, safety, or other impacts of GE crops and food, and makes recommendations to fill gaps in safety assessments, increase regulatory clarity, and improve innovations in and access to GE technology.

The Pangenome

The Pangenome
Author: Hervé Tettelin
Publsiher: Springer Nature
Total Pages: 307
Release: 2020-01-01
Genre: Biology (General)
ISBN: 9783030382810

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This open access book offers the first comprehensive account of the pan-genome concept and its manifold implications. The realization that the genetic repertoire of a biological species always encompasses more than the genome of each individual is one of the earliest examples of big data in biology that opened biology to the unbounded. The study of genetic variation observed within a species challenges existing views and has profound consequences for our understanding of the fundamental mechanisms underpinning bacterial biology and evolution. The underlying rationale extends well beyond the initial prokaryotic focus to all kingdoms of life and evolves into similar concepts for metagenomes, phenomes and epigenomes. The books respective chapters address a range of topics, from the serendipitous emergence of the pan-genome concept and its impacts on the fields of microbiology, vaccinology and antimicrobial resistance, to the study of microbial communities, bioinformatic applications and mathematical models that tie in with complex systems and economic theory. Given its scope, the book will appeal to a broad readership interested in population dynamics, evolutionary biology and genomics.