Pesticide Biotransformation and Disposition

Pesticide Biotransformation and Disposition
Author: Ernest Hodgson
Publsiher: Academic Press
Total Pages: 234
Release: 2012-01-01
Genre: Medical
ISBN: 9780123854827

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Biotransformation of Pesticides is an updated, "one-stop" resource for academic, industry and regulatory scientists involved in research and regulatory activities related to pesticide biotransformation and human health. This book provides an in depth look at how pesticides are biotransformed, which is essential to understanding exposure, dose, toxicity and health risks. This essential reference contains the biotransformation of pesticides from uptake to excretion, including toxicokinetics and emphasizes metabolism in non-target species, including experimental animals and humans. Includes four new chapters and expanded material on pesticide biotransformation and disposition, an active area of pesticide toxicology that is becoming increasingly important for human health risk assessment Offers a practical and portable guide covering the most up-to-date research results on metabolic transformations of pesticides Provides scientists and regulatory researchers with the information they need to conduct accurate risk assessments and make informed decisions on which exposures to study further in human populations

Intentional Human Dosing Studies for EPA Regulatory Purposes

Intentional Human Dosing Studies for EPA Regulatory Purposes
Author: National Research Council,Policy and Global Affairs,Science, Technology, and Law Program,Committee on the Use of Third Party Toxicity Research with Human Research Participants
Publsiher: National Academies Press
Total Pages: 226
Release: 2004-06-04
Genre: Science
ISBN: 9780309166416

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The EPA commissioned The National Academies to provide advice on the vexing question of whether and, if so, under what circumstances EPA should accept and consider intentional human dosing studies conducted by companies or other sources outside the agency (so-called third parties) to gather evidence relating to the risks of a chemical or the conditions under which exposure to it could be judged safe. This report recommends that such studies be conducted and used for regulatory purposes only if all of several strict conditions are met, including the following: The study is necessary and scientifically valid, meaning that it addresses an important regulatory question that can't be answered with animal studies or nondosing human studies; The societal benefits of the study outweigh any anticipated risks to participants. At no time, even when benefits beyond improved regulation exist, can a human dosing study be justified that is anticipated to cause lasting harm to study participants; and All recognized ethical standards and procedures for protecting the interests of study participants are observed. In addition, EPA should establish a Human Studies Review Board (HSRB) to evaluate all human dosing studiesâ€"both at the beginning and upon completion of the experimentsâ€"if they are carried out with the intent of affecting the agency's policy-making.

Trends and Applications in Information Systems and Technologies

Trends and Applications in Information Systems and Technologies
Author: Álvaro Rocha,Hojjat Adeli,Gintautas Dzemyda,Fernando Moreira,Ana Maria Ramalho Correia
Publsiher: Springer Nature
Total Pages: 623
Release: 2021-03-28
Genre: Technology & Engineering
ISBN: 9783030726515

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This book is composed of a selection of articles from The 2021 World Conference on Information Systems and Technologies (WorldCIST'21), held online between 30 and 31 of March and 1 and 2 of April 2021 at Hangra de Heroismo, Terceira Island, Azores, Portugal. WorldCIST is a global forum for researchers and practitioners to present and discuss recent results and innovations, current trends, professional experiences and challenges of modern information systems and technologies research, together with their technological development and applications. The main topics covered are: A) Information and Knowledge Management; B) Organizational Models and Information Systems; C) Software and Systems Modeling; D) Software Systems, Architectures, Applications and Tools; E) Multimedia Systems and Applications; F) Computer Networks, Mobility and Pervasive Systems; G) Intelligent and Decision Support Systems; H) Big Data Analytics and Applications; I) Human–Computer Interaction; J) Ethics, Computers & Security; K) Health Informatics; L) Information Technologies in Education; M) Information Technologies in Radiocommunications; N) Technologies for Biomedical Applications.

Hayes Handbook of Pesticide Toxicology

Hayes  Handbook of Pesticide Toxicology
Author: Anonim
Publsiher: Academic Press
Total Pages: 2000
Release: 2010-02-15
Genre: Medical
ISBN: 9780080922010

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The Handbook of Pesticide Toxicology is a comprehensive, two-volume reference guide to the properties, effects, and regulation of pesticides that provides the latest and most complete information to researchers investigating the environmental, agricultural, veterinary, and human-health impacts of pesticide use. Written by international experts from academia, government, and the private sector, the Handbook of Pesticide Toxicology is an in-depth examination of critical issues related to the need for, use of, and nature of chemicals used in modern pest management. This updated 3e carries on the book’s tradition of serving as the definitive reference on pesticide toxicology and recognizes the seminal contribution of Wayland J. Hayes, Jr., co-Editor of the first edition. Feature: Presents a comprehensive look at all aspects of pesticide toxicology in one reference work. Benefit: Saves researchers time in quickly accessing the very latest definitive details on toxicity of specific pesticides as opposed to searching through thousands of journal articles. Feature: Clear exposition of hazard identification and dose response relationships in each chapter featuring pesticide agents and actions Benefit: Connects the experimental laboratory results to real-life applications in human health, animal health and the environment. Feature: All major classes of pesticide considered. Benefit: Provides relevance to a wider variety of researchers who are conducting comparative work in pesticides or their health impacts. Feature: Different routes of exposure critically evaluated. Benefit: Connects the loop between exposure and harmful affects to those who are researching the affects of pesticides on humans or wildlife.

Comprehensive Toxicology

Comprehensive Toxicology
Author: Anonim
Publsiher: Elsevier
Total Pages: 8624
Release: 2017-12-01
Genre: Medical
ISBN: 9780081006122

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Comprehensive Toxicology, Third Edition, discusses chemical effects on biological systems, with a focus on understanding the mechanisms by which chemicals induce adverse health effects. Organized by organ system, this comprehensive reference work addresses the toxicological effects of chemicals on the immune system, the hematopoietic system, cardiovascular system, respiratory system, hepatic toxicology, renal toxicology, gastrointestinal toxicology, reproductive and endocrine toxicology, neuro and behavioral toxicology, developmental toxicology and carcinogenesis, also including critical sections that cover the general principles of toxicology, cellular and molecular toxicology, biotransformation and toxicology testing and evaluation. Each section is examined in state-of-the-art chapters written by domain experts, providing key information to support the investigations of researchers across the medical, veterinary, food, environment and chemical research industries, and national and international regulatory agencies. Thoroughly revised and expanded to 15 volumes that include the latest advances in research, and uniquely organized by organ system for ease of reference and diagnosis, this new edition is an essential reference for researchers of toxicology. Organized to cover both the fundamental principles of toxicology and unique aspects of major organ systems Thoroughly revised to include the latest advances in the toxicological effects of chemicals on the immune system Features additional coverage throughout and a new volume on toxicology of the hematopoietic system Presents in-depth, comprehensive coverage from an international author base of domain experts

Comparative Disposition and Biotransformation of Pentachlorophenol in Two Marine Mollusks

Comparative Disposition and Biotransformation of Pentachlorophenol in Two Marine Mollusks
Author: Scott Leigh Shofer
Publsiher: Unknown
Total Pages: 102
Release: 1992
Genre: Abalones
ISBN: UCAL:X49524

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Toxicology Research Projects Directory

Toxicology Research Projects Directory
Author: Anonim
Publsiher: Unknown
Total Pages: 135
Release: 1980-10
Genre: Toxicology
ISBN: UOM:39015010284928

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Recognition and Management of Pesticide Poisonings

Recognition and Management of Pesticide Poisonings
Author: Donald P. Morgan
Publsiher: DIANE Publishing
Total Pages: 207
Release: 1989-06
Genre: Technology & Engineering
ISBN: 9780788131769

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Designed as guidance for emergency management, this manual deals almost entirely with short-term (acute) harmful effects of pesticides. Included is information on the health hazards of pesticides currently in use, along with current consensus recommendations for management of poisonings and injuries caused by them. Formatted for quick reference by through indexing, the book addresses poisoning by insecticides, pesticides, herbicides, fungicides, rodenticides, fumigants, and other solvents, acaricides, repellents, and adjuvants. Indexed by symptoms and signs and by chemical and product names. Illustrated.