Realizing the Promise of Precision Medicine

Realizing the Promise of Precision Medicine
Author: Paul Cerrato,John Halamka
Publsiher: Academic Press
Total Pages: 218
Release: 2017-08-24
Genre: Medical
ISBN: 9780128116364

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Realizing the Promise of Precision Medicine: The Role of Patient Data, Mobile Technology, and Consumer Engagement explains the potential of personalized medicine and the value of those approaches in making that potential a reality. The book helps transform one-size-fits-all healthcare into a system that focuses on individual needs and the unique needs of each family member, discussing topics such as U.S. sponsored precision medicine initiative, genomics, the role of electronic health records and mobile medicine, patient engagement and empowerment, health information exchange and patient data protection. In addition, the book discusses the barriers and limitations of precision medicine and how to overcome them. Readers will find valuable insights into how big data, patient engagement, mobile technology, and genomics help individualize medical care and offer a pathway to help detect many undiscovered causes of diseases. Provides drawings and flow charts to help readers visualize the breadth and depth of precision medicine Includes sidebars with more details on specific topics for a complementary, deeper understanding of the main text Uses case studies to turn abstract concepts into flesh and blood examples of how personalized medicine benefits patients

Continuing Americas Leadership

Continuing Americas Leadership
Author: United States. Congress,Committee on Health Education Labor and Pensions,United States Senate
Publsiher: Unknown
Total Pages: 46
Release: 2017-08-20
Genre: Electronic Book
ISBN: 1974656640

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Continuing America's leadership : realizing the promise of precision medicine for patients : hearing of the Committee on Health, Education, Labor, and Pensions, United States Senate, One Hundred Fourteenth Congress, first session ... May 5, 2015.

Continuing America s leadership

Continuing America s leadership
Author: United States. Congress. Senate. Committee on Health, Education, Labor, and Pensions
Publsiher: Unknown
Total Pages: 41
Release: 2017
Genre: Drug development
ISBN: OCLC:1097447755

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Economic Dimensions of Personalized and Precision Medicine

Economic Dimensions of Personalized and Precision Medicine
Author: Ernst R. Berndt
Publsiher: National Bureau of Economic Re
Total Pages: 392
Release: 2019-04-22
Genre: Business & Economics
ISBN: 9780226611068

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Personalized and precision medicine (PPM)--the targeting of therapies according to an individual's genetic, environmental, or lifestyle characteristics--is becoming an increasingly important approach in health care treatment and prevention. The advancement of PPM is a challenge in traditional clinical, reimbursement, and regulatory landscapes because it is costly to develop and introduces a wide range of scientific, clinical, ethical, and socioeconomic issues. PPM raises a multitude of economic issues, including how information on accurate diagnosis and treatment success will be disseminated and who will bear the cost; changes to physician training to incorporate genetics, probability and statistics, and economic considerations; questions about whether the benefits of PPM will be confined to developed countries or will diffuse to emerging economies with less developed health care systems; the effects of patient heterogeneity on cost-effectiveness analysis; and opportunities for PPM's growth beyond treatment of acute illness, such as prevention and reversal of chronic conditions. This volume explores the intersection of the scientific, clinical, and economic factors affecting the development of PPM, including its effects on the drug pipeline, on reimbursement of PPM diagnostics and treatments, and on funding of the requisite underlying research; and it examines recent empirical applications of PPM.

Economic Dimensions of Personalized and Precision Medicine

Economic Dimensions of Personalized and Precision Medicine
Author: Ernst R. Berndt,Dana P. Goldman,John Rowe
Publsiher: University of Chicago Press
Total Pages: 400
Release: 2019-04-22
Genre: Business & Economics
ISBN: 9780226611235

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Personalized and precision medicine (PPM)—the targeting of therapies according to an individual’s genetic, environmental, or lifestyle characteristics—is becoming an increasingly important approach in health care treatment and prevention. The advancement of PPM is a challenge in traditional clinical, reimbursement, and regulatory landscapes because it is costly to develop and introduces a wide range of scientific, clinical, ethical, and socioeconomic issues. PPM raises a multitude of economic issues, including how information on accurate diagnosis and treatment success will be disseminated and who will bear the cost; changes to physician training to incorporate genetics, probability and statistics, and economic considerations; questions about whether the benefits of PPM will be confined to developed countries or will diffuse to emerging economies with less developed health care systems; the effects of patient heterogeneity on cost-effectiveness analysis; and opportunities for PPM’s growth beyond treatment of acute illness, such as prevention and reversal of chronic conditions. This volume explores the intersection of the scientific, clinical, and economic factors affecting the development of PPM, including its effects on the drug pipeline, on reimbursement of PPM diagnostics and treatments, and on funding of the requisite underlying research; and it examines recent empirical applications of PPM.

Toward Precision Medicine

Toward Precision Medicine
Author: National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Committee on A Framework for Developing a New Taxonomy of Disease
Publsiher: National Academies Press
Total Pages: 142
Release: 2012-01-16
Genre: Medical
ISBN: 9780309222228

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Motivated by the explosion of molecular data on humans-particularly data associated with individual patients-and the sense that there are large, as-yet-untapped opportunities to use this data to improve health outcomes, Toward Precision Medicine explores the feasibility and need for "a new taxonomy of human disease based on molecular biology" and develops a potential framework for creating one. The book says that a new data network that integrates emerging research on the molecular makeup of diseases with clinical data on individual patients could drive the development of a more accurate classification of diseases and ultimately enhance diagnosis and treatment. The "new taxonomy" that emerges would define diseases by their underlying molecular causes and other factors in addition to their traditional physical signs and symptoms. The book adds that the new data network could also improve biomedical research by enabling scientists to access patients' information during treatment while still protecting their rights. This would allow the marriage of molecular research and clinical data at the point of care, as opposed to research information continuing to reside primarily in academia. Toward Precision Medicine notes that moving toward individualized medicine requires that researchers and health care providers have access to very large sets of health- and disease-related data linked to individual patients. These data are also critical for developing the information commons, the knowledge network of disease, and ultimately the new taxonomy.

The Transformative Power of Mobile Medicine

The Transformative Power of Mobile Medicine
Author: Paul Cerrato,John Halamka
Publsiher: Academic Press
Total Pages: 232
Release: 2019-01-23
Genre: Business & Economics
ISBN: 9780128149249

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The Transformative Power of Mobile Medicine: Leveraging Innovation, Seizing Opportunities, and Overcoming Obstacles of mHealth addresses the rapid advances taking place in mHealth and their impact on clinicians and patients. It provides guidance on reliable mobile health apps that are based on sound scientific evidence, while also offering advice on how to stay clear of junk science. The book explores the latest developments, including the value of blockchain, the emerging growth of remote sensors in chronic patient care, the potential use of Amazon Alexa and Google Assistant as patient bedside assistants, the use of Amazon’s IoT button, and much more. This book enables physicians and nurses to gain a deep understanding of the strengths and weaknesses of mobile health and helps them choose evidence-based mobile medicine tools to improve patient care. Provides clinicians and technologists with an update on the latest mobile health initiatives and tools, including the work done at Beth Israel Deaconess Medical Center/Harvard Medical School Encompasses case studies with real-world examples to turn abstract concepts into flesh and blood examples of how mHealth benefits the public Presents drawings, graphics and flow charts to help readers visualize the functionality and value of mobile medicine

Law and Economics of Personalized Medicine

Law and Economics of Personalized Medicine
Author: Karin Bosshard
Publsiher: Springer
Total Pages: 411
Release: 2018-05-14
Genre: Law
ISBN: 9783658220747

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The book adds to the discussion about strategic approaches towards the translation of personalized medicine into clinical practice. It stresses the importance of non-science related, institutional barriers. A Law and Economics perspective is applied in order to examine the incentives induced by the barriers. An applied part identifies and evaluates policy levers to foster the translation of personalized medicine into Swiss clinical practice.