Studies in Natural Products Chemistry

Studies in Natural Products Chemistry
Author: Atta-ur- Rahman
Publsiher: Elsevier
Total Pages: 438
Release: 2012-12-06
Genre: Science
ISBN: 9780444595157

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Natural products play an integral and ongoing role in promoting numerous aspects of scientific advancement, and many aspects of basic research programs are intimately related to natural products. With articles written by leading authorities in their respective fields of research, Studies in Natural Products Chemistry, Volume 37 presents current frontiers and future guidelines for research based on important discoveries made in the field of bioactive natural products. It is a valuable source for researchers and engineers working in natural products and medicinal chemistry. Describes the chemistry of bioactive natural products Contains contributions by leading authorities in the field A valuable source for researchers and engineers working in natural product and medicinal chemistry

Studies in Natural Products Chemistry

Studies in Natural Products Chemistry
Author: Atta-ur-Rahman
Publsiher: Elsevier
Total Pages: 812
Release: 2003-07-08
Genre: Science
ISBN: 0080542050

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Studies in Natural Products Chemistry: Bioactive Natural Products (Part I) contains articles written by leading authorities in their respective fields of research. It presents current frontiers and future guidelines for research based on important discoveries made in the field of bioactive natural products. Volume 28 is part of a great family of useful reference books Illustrates the types of critical discoveries that emerge from the interface of chemistry and biology Contributions are from well-respected authors

Studies in Natural Products Chemistry

Studies in Natural Products Chemistry
Author: Atta-ur-Rahman
Publsiher: Elsevier
Total Pages: 1148
Release: 2011-08-30
Genre: Science
ISBN: 0080458483

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Natural products present in the plant and animal kingdom offer a huge diversity of chemical structures which are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate, determine the structures and biological activity of natural products rapidly, thus opening up exciting new opportunities in the field of new drug development to the pharmaceutical industry. The present volume contains 22 articles written by leading experts in natural product chemistry on biologically active natural products. It includes research on a variety of different classes of natural products including sesquiterpenes, quassinoids, diterpenoids, lignans, oligostilbenes, phenylethanoids, phenylpropanoid glycosides, curcumin analogues, glycosphingolipids etc. Many of these have been found to be active in a number of different disease conditions. * Timely reviews written by international authorities in the field * Topics ranging from purely chemical to very biological * The 13th volume in the series to be devoted to bioactive natural products

Introduction to Natural Products Chemistry

Introduction to Natural Products Chemistry
Author: Rensheng Xu,Yang Ye,Weimin Zhao
Publsiher: CRC Press
Total Pages: 381
Release: 2011-07-20
Genre: Medical
ISBN: 9781439860779

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Natural products chemistry-the chemistry of metabolite products of plants, animals and microorganisms-is involved in the investigation of biological phenomena ranging from drug mechanisms to gametophytes and receptors and drug metabolism in the human body to protein and enzyme chemistry. Introduction to Natural Products Chemistry has collected the

Natural Product Chemistry for Drug Discovery

Natural Product Chemistry for Drug Discovery
Author: Antony D. Buss,Mark S. Butler,Royal Society of Chemistry (Great Britain)
Publsiher: Royal Society of Chemistry
Total Pages: 440
Release: 2010
Genre: Medical
ISBN: 9780854041930

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This up-to-date summary of natural product chemistry in drug discovery will appeal to scientists, professionals, postgraduates and industrial chemists.

Natural Product Extraction

Natural Product Extraction
Author: Mauricio A Rostagno,Juliana M Prado
Publsiher: Royal Society of Chemistry
Total Pages: 135
Release: 2015-10-09
Genre: Science
ISBN: 9781782626220

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Natural products are sought after by the food, pharmaceutical and cosmetics industries, and research continues into their potential for new applications. Extraction of natural products in an economic and environmentally-friendly way is of high importance to all industries involved. This book presents a holistic and in-depth view of the techniques available for extracting natural products, with modern and more environmentally-benign methods, such as ultrasound and supercritical fluids discussed alongside conventional methods. Examples and case studies are presented, along with the decision-making process needed to determine the most appropriate method. Where appropriate, scale-up and process integration is discussed. Relevant to researchers in academia and industry, and students aiming for either career path, Natural Product Extraction presents a handy digest of the current trends and latest developments in the field with concepts of Green Chemistry in mind.

Medicinal Chemistry of Bioactive Natural Products

Medicinal Chemistry of Bioactive Natural Products
Author: Xiao-Tian Liang,Wei-Shuo Fang
Publsiher: John Wiley & Sons
Total Pages: 336
Release: 2006-03-17
Genre: Science
ISBN: 9780471739333

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Current discoveries and research into bioactive naturalproducts Medicinal Chemistry of Bioactive Natural Products provides amuch-needed survey of bioactive natural products and theirapplications in medicinal chemistry. This comprehensive referencefeatures articles by some of the world's leading scientists in thefield on discovery, structure elucidation, and elegant syntheticstrategies--developed for natural products--with an emphasis on thestructure activity relationship of bioactive natural products. Thetopics have been carefully chosen on the basis of relevance tocurrent research and to importance as clinicially usefulagents. Rather than attempting to be a comprehensive encyclopedia ofbioactive natural products, Medicinal Chemistry of BioactiveNatural Products guides the reader to the key developments in thefield. By providing not only practical detail but a historicalperspective on the chemistry and biology of the compounds underconsideration, the book serves as a handy resource for researchersin their own work developing pharmaceuticals, and as an inspiringintroduction for young scientists to the dynamic field of bioactivenatural products research. Enhanced by examples with updated research results, the discussioncovers such topics as: * The chemistry and biology of epothilones * Vancomycin and other glycopeptide antibiotic derivates * Antitumor and other related activities of Taxol and itsanalogs * The antimalarial properties of the traditional Chinese medicine,Quinghaosu (artemisinin) * Huperzine A: A natural drug for the treatment of Alzheimer'sdisease * The medicinal chemistry of ginkgolides from Ginkgo biloba * Recent progress in Calophyllum coumarins as potent anti-HIVagents * Plant-derived anti-HIV agents and analogs * Chemical synthesis of annonaceous acetogenins and theirstructurally modified mimics

Chemistry for Pharmacy Students

Chemistry for Pharmacy Students
Author: Professor Satyajit D. Sarker,Lutfun Nahar
Publsiher: John Wiley & Sons
Total Pages: 400
Release: 2013-05-28
Genre: Science
ISBN: 9781118687536

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"This book has succeeded in covering the basic chemistryessentials required by the pharmaceutical science student…the undergraduate reader, be they chemist, biologist or pharmacistwill find this an interesting and valuable read."–Journal of Chemical Biology, May 2009 Chemistry for Pharmacy Students is a student-friendlyintroduction to the key areas of chemistry required by all pharmacyand pharmaceutical science students. The book provides acomprehensive overview of the various areas of general, organic andnatural products chemistry (in relation to drug molecules). Clearly structured to enhance student understanding, the book isdivided into six clear sections. The book opens with an overview ofgeneral aspects of chemistry and their importance to modern life,with particular emphasis on medicinal applications. The text thenmoves on to a discussion of the concepts of atomic structure andbonding and the fundamentals of stereochemistry and theirsignificance to pharmacy- in relation to drug action and toxicity.Various aspects of aliphatic, aromatic and heterocyclic chemistryand their pharmaceutical importance are then covered with finalchapters looking at organic reactions and their applications todrug discovery and development and natural products chemistry. accessible introduction to the key areas of chemistry requiredfor all pharmacy degree courses student-friendly and written at a level suitable fornon-chemistry students includes learning objectives at the beginning of eachchapter focuses on the physical properties and actions of drugmolecules

Natural Products Chemistry

Natural Products Chemistry
Author: Raymond Cooper,George Nicola
Publsiher: CRC Press
Total Pages: 206
Release: 2014-07-29
Genre: Medical
ISBN: 9781466567610

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Notoriously cumbersome to isolate and challenging to synthesize, the path of natural products to viable drugs is an arduous journey. Yet compounds isolated from nature may possess fascinating structures, biological profiles and pharmaceutical potential far greater than anything made by man. Natural Products Chemistry: Sources, Separations and Structures presents a practical guide to sourcing, isolating, and discovering new compounds from nature many of which become pharmaceutical drugs. This book emphasizes the challenges and advantages of products acquired from nature, compared to those obtained from combinatorial chemistry. A basic introduction, the book describes the whole cycle from farm to final compound, backed up by case studies drawn from industry and research applications. It broadens the scope of applications and draws upon examples from various sources. Natural products chemistry, as taught today, draws its examples mainly from marine chemistry or plant chemistry; however, there is also a fascinating and rich world of fermented (microbial and algal) products leading to complex structures. Thus, the book draws upon examples from the microbial world and from insects too. Therefore, this is a source of bioactive metabolites, not traditionally available in academic settings, more the mainstay of the pharmaceutical industry. Providing a roadmap of the process of collecting a compound from nature, isolating the active ingredient, and determining the chemical structure, this book provides a unique approach to the world of natural products.

Bioactive Natural Products

Bioactive Natural Products
Author: Goutam Brahmachari
Publsiher: John Wiley & Sons
Total Pages: 544
Release: 2015-03-23
Genre: Science
ISBN: 9783527337941

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Natural compounds, which have evolved their function over millions of years, are often more efficient than man-made compounds if a specific biological activity is needed, e.g. as an enzyme inhibitor or as a toxin to kill a cancer cell. This book comprising of sixteen technical chapters, highlights the chemical and biological aspects of potential natural products with an intention of unravelling their pharmaceutical applicability in modern drug discovery processes. Key features: Covers the synthesis, semi-synthesis and also biosynthesis of potentially bioactive natural products Features chemical and biological advances in naturally occurring organic compounds describing their chemical transformations, mode of actions, and structure-activity relationships 40 expert scientists from around the world report their latest findings and outline future opportunities for the development of novel and highly potent drugs based on natural products operating at the interface of chemistry and biology Forward-looking: Addresses opportunities and cutting-edge developments rather than well-documented basic knowledge, pinpoints current trends and future directions in this rapidly-evolving field Application-oriented: Throughout the book, the focus is on actual and potential applications in pharmacology and biotechnology This book is an essential resource for natural products chemists, medicinal chemists, biotechnologists, biochemists, pharmacologists, as well as the pharmaceutical and biotechnological industries.

Natural Products Pharmacology and Phytochemicals for Health Care

Natural Products Pharmacology and Phytochemicals for Health Care
Author: Debarshi Kar Mahapatra,Cristóbal Noé Aguilar,A. K. Haghi
Publsiher: CRC Press
Total Pages: 258
Release: 2021-02-22
Genre: Business & Economics
ISBN: 9781000095579

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Medicinal chemistry and pharmacology are closely associated fields, and the use of natural products for their medicinal properties is ever-growing. The study of drugs from natural products and their effects on the living body are explored in this volume. The book looks into the research, discovery, and characterization of chemicals that exhibit biological effects. Providing an informative compilation of research, valuable case studies, and reviews of existing literature in the area, the book focuses on the ethnobotanical uses of natural products and phytochemicals for health care, including applications for diabetes, ulcers, wound healing, chronic alcoholism, hemorrhoidal treatment, cancer mitigation, pain management, immunotherapy, and more.

Selected Topics in the Chemistry of Natural Products

Selected Topics in the Chemistry of Natural Products
Author: Raphael Ikan
Publsiher: World Scientific
Total Pages: 604
Release: 2008
Genre: Science
ISBN: 9789812705693

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A New York Times Notable Book for 2011 A Globe and Mail Best Books of the Year 2011 Title A Kirkus Reviews Best Nonfiction of 2011 title Virtually all human societies were once organized tribally, yet over time most developed new political institutions which included a central state that could keep the peace and uniform laws that applied to all citizens. Some went on to create governments that were accountable to their constituents. We take these institutions for granted, but they are absent or are unable to perform in many of today’s developing countries—with often disastrous consequences for the rest of the world. Francis Fukuyama, author of the bestselling The End of History and the Last Man and one of our most important political thinkers, provides a sweeping account of how today’s basic political institutions developed. The first of a major two-volume work, The Origins of Political Order begins with politics among our primate ancestors and follows the story through the emergence of tribal societies, the growth of the first modern state in China, the beginning of the rule of law in India and the Middle East, and the development of political accountability in Europe up until the eve of the French Revolution. Drawing on a vast body of knowledge—history, evolutionary biology, archaeology, and economics—Fukuyama has produced a brilliant, provocative work that offers fresh insights on the origins of democratic societies and raises essential questions about the nature of politics and its discontents.

Frontiers in Natural Product Chemistry Volume 4

Frontiers in Natural Product Chemistry  Volume 4
Author: Atta-ur-Rahman
Publsiher: Bentham Science Publishers
Total Pages: 307
Release: 2018-10-08
Genre: Medical
ISBN: 9781681087252

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Frontiers in Natural Product Chemistry is a book series devoted to publishing monographs that highlight important advances in natural product chemistry. The series covers all aspects of research in the chemistry and biochemistry of naturally occurring compounds, including research on natural substances derived from plants, microbes and animals. Reviews of structure elucidation, biological activity, organic and experimental synthesis of natural products as well as developments of new methods are also included in the series. The fourth volume of the series brings seven reviews covering these topics: -natural antiamoebic medicines, analgesics and antimalarials -essential oils and cognitive performance -cannabis and drug development -lectins in biosensors -brassinosteroids

Natural Materials and Products from Insects Chemistry and Applications

Natural Materials and Products from Insects  Chemistry and Applications
Author: Dhiraj Kumar,Mohammad Shahid
Publsiher: Springer Nature
Total Pages: 156
Release: 2020-02-28
Genre: Science
ISBN: 9783030366100

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This book reviews the latest research on bioproducts from various economically important insects, such as silkworms, honey bees, lac and drosophila, and termites, and discusses their general, biomedical and industrial applications in detail. It includes chapters focusing on insects as a food source, probiotics, silk-based biomaterials, insect pheromones, insects as biomedicine source, pupa oil chemistry, non-protein compounds from Lepidopteran insects, insect chitin and chitosan, polyphenols and flavonoids. Model insects like Bombyx mori or bees were domesticated in Asian countries thousands of years ago. Over time, natural products from these animals became industrialized and today they attracting increasing attention thanks to their sustainability and their manifold applications in agriculture and biomedicine. The book is intended for entomologists, material scientists, natural product researchers and biotechnologists.

Natural Products Chemistry of Botanical Medicines from Cameroonian Plants

Natural Products Chemistry of Botanical Medicines from Cameroonian Plants
Author: Xavier Siwe-Noundou
Publsiher: CRC Press
Total Pages: 220
Release: 2021-09-28
Genre: Science
ISBN: 9780429015212

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A contribution to the series on Natural Products Chemistry of Global Plants, Natural Products Chemistry of Botanical Medicines from Cameroon focuses on the sources and chemistry of natural products from plants in Cameroon, West Africa. The plants selected offer an opportunity to trace a route through history from ancient civilizations to the modern day, showing the important value to man of natural products in medicines and in foods. This book highlights how many of the extracts from Cameroon are today associated with important drugs, nutrition products, beverages, perfumes, cosmetics and pigments, as well as presenting their complex chemistry and structure. Key Features: Forms an important part of the series on Natural Products Chemistry of Global Plants, as Cameroon is a country with rich experience in the use of medicinal plants and with a wide diversity of botanical resources Addresses the current development of pharmacognosy research in Cameroon Provides readers with updated information on the chemistry and pharmacology of natural products with pharmaceutical potential Covers an extensive range of chemical, botanical and pharmacological diversities Xavier Siwe Noundou is a Scholar/Scientist based at Rhodes University in Grahamstown, South Africa. He has been a EU FP7 Marie Curie Fellow (2015-2016), Kaposvar University in Hungary (2015, 2016), Trakia Univesity in Bulgaria (2016), TWAS Fellow (2013), National Research Foundation South Africa Fellow (2014-2016). Dr Noundou works on Medicinal Chemistry focusing on Chemistry, Pharmacognosy and Nanotechnology. His main research interests include terrestrial natural products chemistry (from Cameroon and South Africa) and marine natural products chemistry (from the South African coastline): bioactive metabolites isolated as potential antiparasitic, antimicrobial, antiviral and antiproliferative candidates. He is author of more than forty scientific publications in his field of expertise.