Textbook of Nephro Endocrinology

Textbook of Nephro Endocrinology
Author: Ajay K. Singh,Gordon H. Williams
Publsiher: Academic Press
Total Pages: 584
Release: 2017-12-15
Genre: Medical
ISBN: 9780128032480

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Textbook of Nephro-Endocrinology, Second Edition, continues to be the definitive translational reference in the field of nephro-endocrinology, investigating both the endocrine functions of the kidneys and how the kidney acts as a target for hormones from other organ systems. It offers researchers and clinicians expert analyses of nephro-endocrine research and translation into the treatment of diseases such as anemia, chronic kidney disease (CKD), rickets, osteoporosis, and hypoparathyroidism. Changes to this edition include new chapters focused on hypercalcemia/hypocalcemia and the interaction of dialysis, chronic renal disease, and endocrine diseases. All chapters have been updated to include more preclinical data and more tables and schema that help translate this data into clinical recommendations. The section on hormones and renal insufficiency discusses insulin/diabetes, growth hormone, sex steroids, thyroid hormone, acid–base disturbances, and pregnancy. Presents a uniquely comprehensive and cross-disciplinary look at all aspects of nephro-endocrine disorders in one reference Investigates both the endocrine functions of the kidneys and how the kidney acts as a target for hormones from other organ systems Offers clear translational presentations by the top endocrinologists and nephrologists in each specific hormone or functional/systems field Features new and updated chapters that include more tables and schema to help translate preclinical data into clinical recommendations

Textbook of Nephro Endocrinology Second Edition

Textbook of Nephro Endocrinology  Second Edition
Author: Gordon H. Williams
Publsiher: Unknown
Total Pages: 135
Release: 2017
Genre: Electronic Book
ISBN: 0323239900

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Endocrinology of the Heart in Health and Disease

Endocrinology of the Heart in Health and Disease
Author: Jonathan C. Schisler,Charles H Lang,Monte Willis
Publsiher: Academic Press
Total Pages: 378
Release: 2016-10-19
Genre: Medical
ISBN: 9780128031124

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Endocrinology of the Heart in Health and Disease: Integrated, Cellular, and Molecular Endocrinology of the Heart covers the traditional concepts of cardio-endocrinology, the role of the various hormone systems, both in health and disease, therapeutic implications, and other recent advances in the various fields represented. The book explores how cardiac hormones are changed in various cardiac pathologies and the recent success that has been uncovered in their therapeutic use. Additional focus is placed on how the heart responds both physiologically and pathophysiologically to a plethora of circulating hormones, reinforcing the importance of the heart as a target of numerous endocrine systems, such as the brain, renal, and adipose. Significant advances have come from basic, clinical, and translational research from a multiplicity of investigators with diverse backgrounds. The book features over 200 photomicrographs, diagrams of molecular relationships, and tables that complement and support the text. It is aimed at a wide audience, including graduate students and post-doctoral fellows in a wide array of biomedical departments and PhD programs (e.g. Pathology, Physiology, Genetics, Pharmacology, Molecular Biology, and Cell Biology) related to the endocrine and cardiovascular sciences curricula, as well as medical residents in pathology, laboratory medicine, internal medicine, and cardiology. Develops the concept of the heart as both an endocrine organ and an endocrine target, exploring the endocrine function of the heart in both health and disease Explains how the levels of several cardiac hormones are changed in various cardiac pathologies and how some hormones can be used therapeutically Offers a single resource on cardio-endocrine disease which collates and curates the wide range of advances being made in the areas of molecular biology, biochemistry, physiology, and pathology

Oxford Textbook of Clinical Nephrology Volume 3

Oxford Textbook of Clinical Nephrology Volume 3
Author: Alex M. Davison
Publsiher: Oxford University Press, USA
Total Pages: 2749
Release: 2005
Genre: Kidneys
ISBN: 0198567987

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Authoritative, well-written, and comprehensive textbook of clinical nephrology, combining the clinical aspects of renal disease important for daily clinical practice while giving extensive information about the underlying basic science and current evidence available. This new edition highlights the numerous changes in clinical management that have arisen as a result of recently concluded clinical trials and there are now specific formal guidelines for optimal treatment of patients. Each section of the textbook has been critically and comprehensively edited under the auspices of one of the leading experts in the field. The emphasis throughout is on marrying advances in scientific research with clinical managment. Where possible treatment algorithms are included to aid patient care.

Comprehensive Clinical Nephrology E Book

Comprehensive Clinical Nephrology E Book
Author: Richard J. Johnson,John Feehally,Jurgen Floege
Publsiher: Elsevier Health Sciences
Total Pages: 1320
Release: 2014-09-05
Genre: Medical
ISBN: 9780323242875

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Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. The right amount of basic science and practical clinical guidance assists in making efficient and informed decisions. Extensive updates on key topics keep you at the forefront of the field. New chapters on glomerulonephritis associated with complement disorders, interventional treatments for hypertension, renal disease and cancer, and epidemiology and prognostic impact of acute kidney injury. Over 1,500 color illustrations highlight key topics and detail pathogenesis for a full range of kidney conditions and clinical management. Hundreds of color coded algorithms promote quick reference and to help you retain concepts. Over 400 NEW self-assessment questions available at Expert Consult.

Chronic Renal Disease

Chronic Renal Disease
Author: Paul L. Kimmel,Mark E. Rosenberg
Publsiher: Elsevier
Total Pages: 930
Release: 2014-09-26
Genre: Medical
ISBN: 9780124116160

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Chronic Renal Disease comprehensively investigates the physiology, pathophysiology, treatment, and management of chronic kidney disease (CKD). This translational reference takes an in-depth look at CKD while excluding coverage of dialysis or transplantation, which are both well detailed in other textbooks and references. Chapters in the basic science sections are devoted to the scientific underpinnings of the development and progression of CKD, including consideration of different etiologic factors. Chapters in the treatment and management sections are geared towards the most common problems faced by nephrologists in the management of CKD. Each chapter relates specific illnesses to the CKD framework instead of covering only the specific illness. Readers will learn, for example, how the management of CKD in a patient with diabetic nephropathy differs from that of other CKD patients. Chapters indicate which unique complications the reader needs to be aware of when treating a specific patient or disease. Chronic Renal Disease includes a companion web-based question and answer supplement to each chapter. This is a valuable resource to reinforce the content of the chapters. The questions are multiple-choice, clinically focused and include referenced discussions of answers. The questions can be used for medical student, resident and fellow teaching, preparation for board or maintenance of certification examinations, and clinician teaching or conference preparation. Provides a useful resource to professors who need to create lectures for residents and fellows, and to identify and summarize relevant literature as it relates to various research projects Includes multiple choice questions and answers, which can be used as a teaching tool for conferences and continuing medical education activities Includes coverage of classification and measurement, epidemiology, pathophysiology, complications of CKD, fluid / electrolyte disorders in CKD, CKD and systemic illnesses, clinical considerations, therapeutic considerations, and special considerations

Contemporary Natural Philosophy and Philosophies Part 2

Contemporary Natural Philosophy and Philosophies   Part 2
Author: Marcin J. Schroeder,Gordana Dodig-Crnkovic
Publsiher: MDPI
Total Pages: 196
Release: 2020-11-19
Genre: Philosophy
ISBN: 9783039435357

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Modern technology has eliminated barriers posed by geographic distances between people around the globe, making the world more interdependent. However, in spite of global collaboration within research domains, fragmentation among research fields persists and even escalates. Disintegrated knowledge has become subservient to the competition in the technological and economic race, leading in the direction chosen not by reason and intellect but rather by the preferences of politics and markets. To restore the authority of knowledge in guiding humanity, we have to reconnect its scattered isolated parts and offer an evolving and diverse but shared vision of objective reality connecting the sciences and other knowledge domains and informed by and in communication with ethical and esthetic thinking and being. This collection of articles responds to the second call from the journal Philosophies to build a new, networked world of knowledge with domain specialists from different disciplines interacting and connecting with the rest of the knowledge-producing and knowledge-consuming communities in an inclusive, extended natural-philosophic, human-centric manner. In this process of reconnection, scientific and philosophical investigations enrich each other, with sciences informing philosophies about the best current knowledge of the world, both natural and human-made, while philosophies scrutinize the ontological, epistemological, and methodological foundations of sciences.

Pediatric Bone

Pediatric Bone
Author: Francis H. Glorieux,John M. Pettifor,Harald Jüppner
Publsiher: Academic Press
Total Pages: 853
Release: 2012
Genre: Medical
ISBN: 9780123820402

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Pediatric Bone is the first book to be published to deal exclusively with the biology and diseases of bone as they affect children. Rapid advances have been made in our understanding of the mechanisms and factors controlling the growth and development of bone, and these are discussed in detail in this book. Further, the various diseases of bone which are peculiar to children are highlighted and discussed in the light of our current knowledge with regard to the causation, clinical signs and treatment. The book is aimed to provide those clinicians interested in children's diseases and basic scientists with a comprehensive resource covering the various aspects of bone health and disease in children Key Features * Deals exclusively with bone development and diseases of children and each chapter written by an * Fully referenced providing an appendix of usually difficult to find information on the investigation of pediatric bone disease and reference values * Covers both the physiology of bone and mineral homeostasis in children and diseases in one book * Includes a CD-ROM of images

Oxford Textbook of Clinical Nephrology Volume 1

Oxford Textbook of Clinical Nephrology Volume 1
Author: Alex M. Davison
Publsiher: Unknown
Total Pages: 2749
Release: 2005
Genre: Kidneys
ISBN: 9780198567967

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Authoritative, well-written, and comprehensive textbook of clinical nephrology, combining the clinical aspects of renal disease important for daily clinical practice while giving extensive information about the underlying basic science and current evidence available. This new edition highlights the numerous changes in clinical management that have arisen as a result of recently concluded clinical trials and there are now specific formal guidelines for optimal treatment of patients. Each section of the textbook has been critically and comprehensively edited under the auspices of one of the leading experts in the field. The emphasis throughout is on marrying advances in scientific research with clinical managment. Where possible treatment algorithms are included to aid patient care.

Diabetes and Kidney Disease

Diabetes and Kidney Disease
Author: Edgar V. Lerma
Publsiher: Springer Nature
Total Pages: 673
Release: 2021
Genre: Diabetic nephropathies
ISBN: 9783030860202

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This book provides a concise yet comprehensive resource on Diabetic Kidney Disease. Similar to the previous edition, the book reviews the most up-to-date research on diabetic nephropathy, the current understanding of its pathophysiology, renal structural alterations and clinical features, and summarizes recent evidence-based clinical treatment modalities for the prevention and management of diabetic kidney disease. General clinical aspects are also covered, as well as an overview to the novel approaches being designed by leading researchers in the field. A convenient compendium for physicians involved in the care of diabetic patients with varying degrees of kidney involvement, Diabetes and Kidney Disease, 2e is also a handy resource for medical residents and students interested in the current status and future approaches to reducing the burden of diabetes and diabetic kidney disease.

Frailty and Sarcopenia

Frailty and Sarcopenia
Author: Yannis Dionyssiotis
Publsiher: BoD – Books on Demand
Total Pages: 254
Release: 2017-08-30
Genre: Medical
ISBN: 9789535134831

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Frailty is considered a multisystem impairment that makes an individual vulnerable to external or internal stressors. Sarcopenia, the age-dependent loss of muscle mass and function, is proposed as the biological substrate and the pathway whereby the consequences of physical frailty develop. These syndromes are associated with a negative impact in quality of life and can lead to the occurrence of disability, institutionalization, and even mortality. The book focuses upon all the related aspects of frailty and sarcopenia and the new advancements in the related treatments including complex issues and research. It includes high-quality chapters in all related aspects for the syndromes of sarcopenia and frailty, which adversely affect the function and overall effectiveness of the musculoskeletal system and interventions to promote rehabilitation.

Polymer Protein Conjugates

Polymer Protein Conjugates
Author: Gianfranco Pasut,Samuel Zalipsky
Publsiher: Elsevier
Total Pages: 512
Release: 2019-10-30
Genre: Technology & Engineering
ISBN: 9780444640826

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Polymer–Protein Conjugates: From Pegylation and Beyond helps researchers by offering a unique reference and guide into this fascinating area. Sections cover the challenges surrounding the homogeneity of conjugates, their purity and polymer toxicity on long-term use, and how to deal with the risk of immunogenicity. These discussions help researchers design new projects by taking into account the latest innovations for safe and site selective polymer conjugation to proteins. PEG has been the gold standard and likely will play this role for many years, but alternatives are coming into the market, some of which have already been launched. After five decades of improvements, the ideas in this book are entering into a new era of innovation because of the advances in genetic engineering, biochemistry and a better understanding of the results from clinical use of PEG conjugates in humans. Provides an overview on the state-of-the-art of protein polymer conjugation Presents both the pros and cons of polymer-protein conjugates from the point-of-view of their clinical outcomes Outlines advantages and potential risks of present technology based on PEG Offers new alternatives for PEG and new approaches for on site-selective protein modification Identifies future direction of research in this field

Nuclear Receptors

Nuclear Receptors
Author: Mostafa Z. Badr
Publsiher: Springer Nature
Total Pages: 679
Release: 2021-10-30
Genre: Medical
ISBN: 9783030783150

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Nuclear receptors are ligand activated transcription factors that control numerous biological functions. Consequently, altering activity of these receptors is proposed, and indeed documented, to affect many physiological and pathological conditions in experimental animals and humans. Thus, nuclear receptors have become a major target in the effort to treat numerous diseases. This book will shed light on and emphasize intricate processes involved in designing as well as discovering physiological and pharmacological modulators of these important proteins. World-renowned scientists will share with the reader their professional expertise and extensive experience acquired through decades working with nuclear receptors. Chapters address the various means and consequences of modulating nuclear receptor activity will be presented and discussed. These modulators cover a wide span of moieties ranging from synthetic chemicals to natural products. In addition, the classification of these chemicals ranges from pan agonists to selective agonists and inverse agonists to antagonists. They also include proteolytic means to obliterate the receptor in the event that modulating its activity through canonical pharmacological agents becomes less effective and/or less desirable due to anticipated or experienced toxicities. Modulation of receptor activity may also take place in the absence of a ligand or through manipulating the structure of the receptor itself by controlling posttranslational events.

Oxford Textbook of Clinical Nephrology Volume 2

Oxford Textbook of Clinical Nephrology Volume 2
Author: Alex M. Davison
Publsiher: Unknown
Total Pages: 2749
Release: 2005
Genre: Kidneys
ISBN: 9780198567974

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Authoritative, well-written, and comprehensive textbook of clinical nephrology, combining the clinical aspects of renal disease important for daily clinical practice while giving extensive information about the underlying basic science and current evidence available. This new edition highlights the numerous changes in clinical management that have arisen as a result of recently concluded clinical trials and there are now specific formal guidelines for optimal treatment of patients. Each section of the textbook has been critically and comprehensively edited under the auspices of one of the leading experts in the field. The emphasis throughout is on marrying advances in scientific research with clinical managment. Where possible treatment algorithms are included to aid patient care.

Vitamin D

Vitamin D
Author: David Feldman,J. Wesley Pike,Roger Bouillon,Edward Giovannucci,David Goltzman,Martin Hewison
Publsiher: Academic Press
Total Pages: 1266
Release: 2017-12-18
Genre: Science
ISBN: 9780128099643

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Vitamin D: Volume 2: Health, Disease and Therapeutics, Fourth Edition, authoritatively covers the evidence for new roles for vitamin D, ranging from cardiovascular disease, to cancer, diabetes, inflammatory bowel disease, multiple sclerosis and renal disease. This collection represents a who’s who of vitamin D research and the coverage is appropriately broad, drawing in internal medicine, orthopedics, oncology and immunology. Clinical researchers will gain a strong understanding of the molecular basis for a particular area of focus. Offers a comprehensive reference, ranging from basic bone biology, to biochemistry, to the clinical diagnostic and management implications of vitamin D Saves researchers and clinicians time in quickly accessing the very latest details on the diverse scientific and clinical aspects of Vitamin D, as opposed to searching through thousands of journal articles Chapter authors include the most prominent and well-published names in the field Targets chemistry, metabolism and circulation, mechanisms of action, mineral and bone homeostasis and vitamin D deficiency Presents a clinical focus on disorders, analogs, cancer, immunity, inflammation, disease and therapeutic applications