The Disordered Mind

The Disordered Mind
Author: Eric R. Kandel
Publsiher: Farrar, Straus and Giroux
Total Pages: 304
Release: 2018-08-28
Genre: Science
ISBN: 9780374716103

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A Nobel Prize–winning neuroscientist’s probing investigation of what brain disorders can tell us about human nature Eric R. Kandel, the winner of the Nobel Prize in Physiology or Medicine for his foundational research into memory storage in the brain, is one of the pioneers of modern brain science. His work continues to shape our understanding of how learning and memory work and to break down age-old barriers between the sciences and the arts. In his seminal new book, The Disordered Mind, Kandel draws on a lifetime of pathbreaking research and the work of many other leading neuroscientists to take us on an unusual tour of the brain. He confronts one of the most difficult questions we face: How does our mind, our individual sense of self, emerge from the physical matter of the brain? The brain’s 86 billion neurons communicate with one another through very precise connections. But sometimes those connections are disrupted. The brain processes that give rise to our mind can become disordered, resulting in diseases such as autism, depression, schizophrenia, Parkinson’s, addiction, and post-traumatic stress disorder. While these disruptions bring great suffering, they can also reveal the mysteries of how the brain produces our most fundamental experiences and capabilities—the very nature of what it means to be human. Studies of autism illuminate the neurological foundations of our social instincts; research into depression offers important insights on emotions and the integrity of the self; and paradigm-shifting work on addiction has led to a new understanding of the relationship between pleasure and willpower. By studying disruptions to typical brain functioning and exploring their potential treatments, we will deepen our understanding of thought, feeling, behavior, memory, and creativity. Only then can we grapple with the big question of how billions of neurons generate consciousness itself.

The Disordered Mind

The Disordered Mind
Author: Eric R. Kandel
Publsiher: Robinson
Total Pages: 304
Release: 2021-03-04
Genre: Medical
ISBN: 1472140869

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The Disordered Mind

The Disordered Mind
Author: Eric R. Kandel
Publsiher: Hachette UK
Total Pages: 304
Release: 2018-09-27
Genre: Medical
ISBN: 9781472140852

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Neurological and psychiatric disorders have long been regarded as fundamentally different, depending on whether they appear to affect the brain or the mind. In reality, the brain and the mind are inseparable. Both types of disorder can affect every aspect of brain function: from perception, action, memory and emotion to empathy, social interaction, attention and consciousness. It is easy to view brain disorders as simply tragic or frightening. However, studying where these functions go wrong provides a window on the workings of the healthy brain, and makes it more likely that scientists and clinicians will be able to develop effective treatments or preventative strategies. As individuals, and as a society, we are also able to better empathise with people with disorders of the mind. Building on his pioneering research, Eric R. Kandel illustrates how breakthrough studies of brain disruptions can deepen our understanding of thought, feeling, behaviour, memory and creativity, and perhaps in the future will transform medical care and lead to the development of a unified theory of mind.

Reductionism in Art and Brain Science

Reductionism in Art and Brain Science
Author: Eric Kandel
Publsiher: Columbia University Press
Total Pages: 224
Release: 2016-08-30
Genre: Art
ISBN: 9780231542081

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Are art and science separated by an unbridgeable divide? Can they find common ground? In this new book, neuroscientist Eric R. Kandel, whose remarkable scientific career and deep interest in art give him a unique perspective, demonstrates how science can inform the way we experience a work of art and seek to understand its meaning. Kandel illustrates how reductionism—the distillation of larger scientific or aesthetic concepts into smaller, more tractable components—has been used by scientists and artists alike to pursue their respective truths. He draws on his Nobel Prize-winning work revealing the neurobiological underpinnings of learning and memory in sea slugs to shed light on the complex workings of the mental processes of higher animals. In Reductionism in Art and Brain Science, Kandel shows how this radically reductionist approach, applied to the most complex puzzle of our time—the brain—has been employed by modern artists who distill their subjective world into color, form, and light. Kandel demonstrates through bottom-up sensory and top-down cognitive functions how science can explore the complexities of human perception and help us to perceive, appreciate, and understand great works of art. At the heart of the book is an elegant elucidation of the contribution of reductionism to the evolution of modern art and its role in a monumental shift in artistic perspective. Reductionism steered the transition from figurative art to the first explorations of abstract art reflected in the works of Turner, Monet, Kandinsky, Schoenberg, and Mondrian. Kandel explains how, in the postwar era, Pollock, de Kooning, Rothko, Louis, Turrell, and Flavin used a reductionist approach to arrive at their abstract expressionism and how Katz, Warhol, Close, and Sandback built upon the advances of the New York School to reimagine figurative and minimal art. Featuring captivating drawings of the brain alongside full-color reproductions of modern art masterpieces, this book draws out the common concerns of science and art and how they illuminate each other.

There Is Life After the Nobel Prize

There Is Life After the Nobel Prize
Author: Eric Kandel
Publsiher: Columbia University Press
Total Pages: 129
Release: 2021-12-07
Genre: Science
ISBN: 9780231553469

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One day in 1996, the neuroscientist Eric R. Kandel took a call from his program officer at the National Institute of Mental Health, who informed him that he had been awarded a key grant. Also, the officer said, he and his colleagues thought Kandel would win the Nobel Prize. “I hope not soon,” Kandel’s wife, Denise, said when she heard this. Sociologists had found that Nobel Prize winners often did not contribute much more to science, she explained. In this book, Kandel recounts his remarkable career since receiving the Nobel in 2000—or his experience of proving to his wife that he was not yet “completely dead intellectually.” He takes readers through his lab’s scientific advances, including research into how long-term memory is stored in the brain, the nature of age-related memory loss, and the neuroscience of drug addiction and schizophrenia. Kandel relates how the Nobel Prize gave him the opportunity to reach a far larger audience, which in turn allowed him to discover and pursue new directions. He describes his efforts to promote public understanding of science and to put brain science and art into conversation with each other. Kandel also discusses his return to Austria, which he had fled as a child, and observes Austria’s coming to terms with the Nazi period. Showcasing Kandel’s accomplishments, erudition, and wit, There Is Life After the Nobel Prize is a candid account of the working life of an acclaimed scientist.

The Age of Insight

The Age of Insight
Author: Eric Kandel
Publsiher: Random House
Total Pages: 656
Release: 2012-03-27
Genre: Psychology
ISBN: 9781400068715

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A brilliant book by Nobel Prize winner Eric R. Kandel, The Age of Insight takes us to Vienna 1900, where leaders in science, medicine, and art began a revolution that changed forever how we think about the human mind—our conscious and unconscious thoughts and emotions—and how mind and brain relate to art. At the turn of the century, Vienna was the cultural capital of Europe. Artists and scientists met in glittering salons, where they freely exchanged ideas that led to revolutionary breakthroughs in psychology, brain science, literature, and art. Kandel takes us into the world of Vienna to trace, in rich and rewarding detail, the ideas and advances made then, and their enduring influence today. The Vienna School of Medicine led the way with its realization that truth lies hidden beneath the surface. That principle infused Viennese culture and strongly influenced the other pioneers of Vienna 1900. Sigmund Freud shocked the world with his insights into how our everyday unconscious aggressive and erotic desires are repressed and disguised in symbols, dreams, and behavior. Arthur Schnitzler revealed women’s unconscious sexuality in his novels through his innovative use of the interior monologue. Gustav Klimt, Oscar Kokoschka, and Egon Schiele created startlingly evocative and honest portraits that expressed unconscious lust, desire, anxiety, and the fear of death. Kandel tells the story of how these pioneers—Freud, Schnitzler, Klimt, Kokoschka, and Schiele—inspired by the Vienna School of Medicine, in turn influenced the founders of the Vienna School of Art History to ask pivotal questions such as What does the viewer bring to a work of art? How does the beholder respond to it? These questions prompted new and ongoing discoveries in psychology and brain biology, leading to revelations about how we see and perceive, how we think and feel, and how we respond to and create works of art. Kandel, one of the leading scientific thinkers of our time, places these five innovators in the context of today’s cutting-edge science and gives us a new understanding of the modernist art of Klimt, Kokoschka, and Schiele, as well as the school of thought of Freud and Schnitzler. Reinvigorating the intellectual enquiry that began in Vienna 1900, The Age of Insight is a wonderfully written, superbly researched, and beautifully illustrated book that also provides a foundation for future work in neuroscience and the humanities. It is an extraordinary book from an international leader in neuroscience and intellectual history.

Psychiatry Psychoanalysis and the New Biology of Mind

Psychiatry  Psychoanalysis  and the New Biology of Mind
Author: Eric R. Kandel
Publsiher: American Psychiatric Pub
Total Pages: 440
Release: 2008-05-20
Genre: Medical
ISBN: 1585626848

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Brought together for the first time in a single volume, these eight important and fascinating essays by Nobel Prize-winning psychiatrist Eric Kandel provide a breakthrough perspective on how biology has influenced modern psychiatric thought. Complete with commentaries by experts in the field, Psychiatry, Psychoanalysis, and the New Biology of Mind reflects the author's evolving view of how biology has revolutionized psychiatry and psychology and how potentially could alter modern psychoanalytic thought. The author's unique perspective on both psychoanalysis and biological research has led to breakthroughs in our thinking about neurobiology, psychiatry, and psychoanalysis -- all driven by the central idea that a fuller understanding of the biological processes of learning and memory can illuminate our understanding of behavior and its disorders. These wonderful essays cover the mechanisms of psychotherapy and medications, showing that both work at the same level of neural circuits and synapses, and the implications of neurobiological research for psychotherapy; the ability to detect functional changes in the brain after psychotherapy, which enables us, for the first time, to objectively evaluate the effects of psychotherapy on individual patients; the need for animal models of mental disorders; for example, learned fear, to show how molecules and cellular mechanisms for learning and memory can be combined in various ways to produce a range of adaptive and maladaptive behaviors; the unification of behavioral psychology, cognitive psychology, neuroscience, and molecular biology into the new science of the mind, charted in two seminal reports on neurobiology and molecular biology given in 1983 and 2000; the critical role of synapses and synaptic strength in both short- and long-term learning; the biological and social implications of the mapping of the human genome for medicine in general and for psychiatry and mental health in particular; The author concludes by calling for a revolution in psychiatry, one that can use the power of biology and cognitive psychology to treat the many mentally ill persons who do not benefit from drug therapy. Fascinating reading for psychiatrists, psychoanalysts, social workers, residents in psychiatry, and trainees in psychoanalysis, Psychiatry, Psychoanalysis, and the New Biology of Mind records with elegant precision the monumental changes taking place in psychiatric thinking. It is an invaluable reference work and a treasured resource for thinking about the future.

Unthinkable

Unthinkable
Author: Helen Thomson
Publsiher: HarperCollins
Total Pages: 288
Release: 2018-06-26
Genre: Biography & Autobiography
ISBN: 9780062391186

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An Amazon Best Nonfiction Book of the Month Indiebound Bestseller Award-winning science writer Helen Thomson unlocks the biggest mysteries of the human brain by examining nine extraordinary cases Our brains are far stranger than we think. We take it for granted that we can remember, feel emotion, navigate, empathise and understand the world around us, but how would our lives change if these abilities were dramatically enhanced – or disappeared overnight? Helen Thomson has spent years travelling the world, tracking down incredibly rare brain disorders. In Unthinkable she tells the stories of nine extraordinary people she encountered along the way. From the man who thinks he's a tiger to the doctor who feels the pain of others just by looking at them to a woman who hears music that’s not there, their experiences illustrate how the brain can shape our lives in unexpected and, in some cases, brilliant and alarming ways. Story by remarkable story, Unthinkable takes us on an unforgettable journey through the human brain. Discover how to forge memories that never disappear, how to grow an alien limb and how to make better decisions. Learn how to hallucinate and how to make yourself happier in a split second. Find out how to avoid getting lost, how to see more of your reality, even how exactly you can confirm you are alive. Think the unthinkable.

The Disordered Mind

The Disordered Mind
Author: George Graham
Publsiher: Routledge
Total Pages: 304
Release: 2014-08-07
Genre: Philosophy
ISBN: 9781135160142

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"George Graham is contemporary philosophy’s most gifted and humane writer. The Disordered Mind is a wise, deep, and thorough inquiry into the nature of the human mind and the various ‘creaks, cracks, and crevices’ into which it is prone sometimes to wander." Owen Flanagan, Duke University, USA "The book is a success, it is consistently insightful and humane, and conveys a clear understanding not only of relevant philosophical topics, but also of a much more difficult issue, the relevance of those topics to understanding mental illness." Philip Gerrans, University of Adelaide, Australia "The Disordered Mind is a must read for anyone who is a psychiatrist, psychologist, philosopher, neurologist, or mental health worker. Indeed, it is a must read for any thoughtful person who simply desires to understand more deeply and more realistically the workings of their own mind as well as the workings of the human mind in general." Richard Garrett, Bentley University, USA Mental disorder raises profound questions about the nature of the mind. The Disordered Mind: An Introduction to Philosophy of Mind and Mental Illness is the first book to systematically examine and explain, from a philosophical standpoint, what mental disorder is: its reality, causes, consequences, and more. It is also an outstanding introduction to philosophy of mind from the perspective of mental disorder. Each chapter explores a central question or problem about mental disorder, including: What is mental disorder and can it be distinguished from neurological disorder? What roles should reference to psychological, cultural, and social factors play in the medical/scientific understanding of mental disorder? What makes mental disorders undesirable? Are they diseases? Mental disorder and the mind–body problem Is mental disorder a breakdown of rationality? What is a rational mind? Addiction, responsibility and compulsion Ethical dilemmas posed by mental disorder, including questions of dignity and self-respect. Each topic is clearly explained and placed in both a clinical and philosophical context. Mental disorders discussed include clinical depression, dissociative identity disorder, anxiety, religious delusions, and paranoia. Several non-mental neurological disorders that possess psychological symptoms are also examined, including Alzheimer’s disease, Down’s syndrome, and Tourette’s syndrome. Additional features, such as chapter summaries and annotated further reading, provide helpful tools for those coming to the subject for the first time. Throughout, George Graham draws expertly on issues that cut across philosophy, science, and psychiatry. As such, The Disordered Mind is a superb introduction to the philosophy of mental disorder for students of philosophy, psychology, psychiatry, and related mental health professions. PHILOSOPHY/PSYCHOLOGY

Principles of Neural Science

Principles of Neural Science
Author: Eric R. Kandel,James H. Schwartz,Thomas M. Jessell
Publsiher: Unknown
Total Pages: 1135
Release: 1991
Genre: Anatomy
ISBN: 0838580688

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Patient H M

Patient H M
Author: Luke Dittrich
Publsiher: Random House
Total Pages: 480
Release: 2016-08-09
Genre: Science
ISBN: 9780679643807

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“Oliver Sacks meets Stephen King”* in this propulsive, haunting journey into the life of the most studied human research subject of all time, the amnesic known as Patient H.M. For readers of The Immortal Life of Henrietta Lacks comes a story that has much to teach us about our relentless pursuit of knowledge. Winner of the PEN/E.O. Wilson Literary Science Writing Award • Los Angeles Times Book Prize Winner NAMED ONE OF THE BEST BOOKS OF THE YEAR BY The Washington Post • New York Post • NPR • The Economist • New York • Wired • Kirkus Reviews • BookPage In 1953, a twenty-seven-year-old factory worker named Henry Molaison—who suffered from severe epilepsy—received a radical new version of the then-common lobotomy, targeting the most mysterious structures in the brain. The operation failed to eliminate Henry’s seizures, but it did have an unintended effect: Henry was left profoundly amnesic, unable to create long-term memories. Over the next sixty years, Patient H.M., as Henry was known, became the most studied individual in the history of neuroscience, a human guinea pig who would teach us much of what we know about memory today. Patient H.M. is, at times, a deeply personal journey. Dittrich’s grandfather was the brilliant, morally complex surgeon who operated on Molaison—and thousands of other patients. The author’s investigation into the dark roots of modern memory science ultimately forces him to confront unsettling secrets in his own family history, and to reveal the tragedy that fueled his grandfather’s relentless experimentation—experimentation that would revolutionize our understanding of ourselves. Dittrich uses the case of Patient H.M. as a starting point for a kaleidoscopic journey, one that moves from the first recorded brain surgeries in ancient Egypt to the cutting-edge laboratories of MIT. He takes readers inside the old asylums and operating theaters where psychosurgeons, as they called themselves, conducted their human experiments, and behind the scenes of a bitter custody battle over the ownership of the most important brain in the world. Patient H.M. combines the best of biography, memoir, and science journalism to create a haunting, endlessly fascinating story, one that reveals the wondrous and devastating things that can happen when hubris, ambition, and human imperfection collide. “An exciting, artful blend of family and medical history.”—The New York Times *Kirkus Reviews (starred review)

The Neuroscientist Who Lost Her Mind

The Neuroscientist Who Lost Her Mind
Author: Barbara K. Lipska,Elaine McArdle
Publsiher: HarperCollins
Total Pages: 208
Release: 2018-04-03
Genre: Biography & Autobiography
ISBN: 9781328787279

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In the tradition of My Stroke of Insight and Brain on Fire, this powerful memoir recounts Barbara Lipska's deadly brain cancer and explains its unforgettable lessons about the brain and mind. Neuroscientist Lipska was diagnosed early in 2015 with metastatic melanoma in her brain's frontal lobe. As the cancer progressed and was treated, she experienced behavioral and cognitive symptoms connected to a range of mental disorders, including dementia and her professional specialty, schizophrenia. Lipska's family and associates were alarmed by the changes in her behavior, which she failed to acknowledge herself. Gradually, after a course of immunotherapy, Lipska returned to normal functioning, amazingly recalled her experience, and through her knowledge of neuroscience identified the ways in which her brain changed during treatment. Lipska admits her condition was unusual; after recovery she was able to return to her research and resume her athletic training and compete in a triathalon. Most patients with similar brain cancers rarely survive to describe their ordeal. Lipska's memoir, coauthored with journalist Elaine McArdle, shows that strength and courage but also an encouraging support network are vital to recovery.

Neuro Philosophy and the Healthy Mind Learning from the Unwell Brain

Neuro Philosophy and the Healthy Mind  Learning from the Unwell Brain
Author: Georg Northoff
Publsiher: W. W. Norton & Company
Total Pages: 256
Release: 2016-01-11
Genre: Psychology
ISBN: 9780393709391

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Applying insights from neuroscience to philosophical questions about the self, consciousness, and the healthy mind. Can we “see” or “find” consciousness in the brain? How can we create working definitions of consciousness and subjectivity, informed by what contemporary research and technology have taught us about how the brain works? How do neuronal processes in the brain relate to our experience of a personal identity? Where does the brain end and the mind begin? To explore these and other questions, esteemed philosopher and neuroscientist Georg Northoff turns to examples of unhealthy minds. By investigating consciousness through its absence—in people in vegetative states, for example—we can develop a model for understanding its presence in an active, healthy person. By examining instances of distorted self-recognition in people with psychiatric disorders, like schizophrenia, we can begin to understand how the experience of “self” is established in a stable brain. Taking an integrative approach to understanding the self, consciousness, and what it means to be mentally healthy, this book brings insights from neuroscience to bear on philosophical questions. Readers will find a science-grounded examination of the human condition with far-reaching implications for psychology, medicine, our daily lives, and beyond.

The Body Keeps the Score

The Body Keeps the Score
Author: Bessel van der Kolk, M.D.
Publsiher: Penguin
Total Pages: 464
Release: 2014-09-25
Genre: Psychology
ISBN: 9781101608302

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#1 New York Times bestseller “Essential reading for anyone interested in understanding and treating traumatic stress and the scope of its impact on society.” —Alexander McFarlane, Director of the Centre for Traumatic Stress Studies A pioneering researcher transforms our understanding of trauma and offers a bold new paradigm for healing in this New York Times bestseller Trauma is a fact of life. Veterans and their families deal with the painful aftermath of combat; one in five Americans has been molested; one in four grew up with alcoholics; one in three couples have engaged in physical violence. Dr. Bessel van der Kolk, one of the world’s foremost experts on trauma, has spent over three decades working with survivors. In The Body Keeps the Score, he uses recent scientific advances to show how trauma literally reshapes both body and brain, compromising sufferers’ capacities for pleasure, engagement, self-control, and trust. He explores innovative treatments—from neurofeedback and meditation to sports, drama, and yoga—that offer new paths to recovery by activating the brain’s natural neuroplasticity. Based on Dr. van der Kolk’s own research and that of other leading specialists, The Body Keeps the Score exposes the tremendous power of our relationships both to hurt and to heal—and offers new hope for reclaiming lives.

Dark Persuasion

Dark Persuasion
Author: Joel E. Dimsdale
Publsiher: Yale University Press
Total Pages: 304
Release: 2021-08-10
Genre: Psychology
ISBN: 9780300247176

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A harrowing account of brainwashing’s pervasive role in the twentieth and twenty-first centuries This gripping book traces the evolution of brainwashing from its beginnings in torture and religious conversion into the age of neuroscience and social media. When Pavlov introduced scientific approaches, his research was enthusiastically supported by Lenin and Stalin, setting the stage for major breakthroughs in tools for social, political, and religious control. Tracing these developments through many of the past century’s major conflagrations, Dimsdale narrates how when World War II erupted, governments secretly raced to develop drugs for interrogation. Brainwashing returned to the spotlight during the Cold War in the hands of the North Koreans and Chinese. In response, a huge Manhattan Project of the Mind was established to study memory obliteration, indoctrination during sleep, and hallucinogens. Cults used the techniques as well. Nobel laureates, university academics, intelligence operatives, criminals, and clerics all populate this shattering and dark story—one that hasn’t yet ended.